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  • organomercurial compounds
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  • organomercurial compounds
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  • sulfhydryl compounds
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VF   1) Ventricular Fibrillation
    ? Tx of Ventricular Fibrillation ...
'Greek letter alpha' angular acceleration; first [carbon atom next to the carbon atom bearing the active group in organic...
beta [Greek letter beta] an anomer of a carbohydrate; buffer capacity; carbon separated from a carboxyl by one other carbon i...
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BT Bretylium tosylate
EACs Endocrine active compounds
NOC N-Nitroso compounds
OPC Organophosphorus compounds
PAC Polycyclic aromatic compounds
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  • bretylium tosylate
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  • organochloric compounds poisoning
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  • sulfhydryl compounds
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bretylium <drug> An antihypertensive which on chronic oral dosing diminishes the release of norepinephrine from noradrenergic nerve endings.
Pharmacologic action: Suppress ventricular fibrillation and ventricular tachycardia, initially releases norepinephrine, then prevents synaptic release of norepinephrine; transiently increases myocardial contractility
Uses: Treatment of refractory ventricular fibrillation and pulseless ventricular tachycardia after defibrillation, epinephrine, and lidocaine. Treatment of ventricular tachycardia with a pulse after lidocaine and procainamide. Treatment of wide complex tachycardia of uncertain type after lidocaine and adenosine.
Dose: 5 mg/kg IV initially, then 10 mg/kg every 5-10 minutes to a maximum of 30 mg/kg In persistently recurring ventricular tachycardia, load with 5-10 mg/kg diluted in 50 mL and infuse over 8-10 min. Follow with continuous infusion at 1-2 mg/min
Onset: Transient hypertension and tachycardia lasts about 20 min. Postural hypotension begins about 20 min after injection and peaks about 60 min later.
Potential complications: 1. May cause initial hypertension followed by a decrease in systemic vascular resistance and hypotension. 2. May exacerbate digitalis toxicity
Note: Lidocaine is considered the first line drug for ventricular arrhythmias. Bretylium causes more hemodynamic instability than lidocaine and has not been shown to increase survival more than lidocaine.
(05 Mar 2000)
bretylium tosylate <chemical> An agent that blocks the release of adrenergic transmitters and may have other actions. It was formerly used as an antihypertensive agent, but is now proposed as an anti-arrhythmic.
Pharmacological action: adrenergic agents, anti-arrhythmia agents, antihypertensive agents, sympatholytics.
Chemical name: Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1)
(12 Dec 1998)
alicyclic compounds See: cyclic compound.
(05 Mar 2000)
alkylmercury compounds Organic mercury compounds in which the mercury is attached to an alkyl group.
(12 Dec 1998)
alum compounds Aluminum metal sulfate compounds used medically as astringents and for many industrial purposes. They are used in veterinary medicine for the treatment of ulcerative stomatitis, leukorrhoea, conjunctivitis, pharyngitis, metritis, and minor wounds.
(12 Dec 1998)
aluminum compounds Inorganic compounds that contain aluminum as an integral part of the molecule.
(12 Dec 1998)
aminobiphenyl compounds <chemistry> Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings.
(12 Dec 1998)
ammonium compounds Inorganic and organic compounds that contain the hypothetical radical nh4.
(12 Dec 1998)
barium compounds Inorganic compounds that contain barium as an integral part of the molecule.
(12 Dec 1998)
benzalkonium compounds <chemical> A mixture of alkylbenzyldimethylammonium compounds. It is a bactericidal quaternary ammonium detergent used topically in medicaments, deodorants, mouthwashes, as a surgical antiseptic, and as a as preservative and emulsifier in drugs and cosmetics.
Pharmacological action: anti-infective agents, local, detergents, preservatives, pharmaceutical.
(12 Dec 1998)
benzhydryl compounds Compounds which contain the methyl radical substituted with two benzene rings. Permitted are any substituents, but ring fusion to any of the benzene rings is not allowed.
(12 Dec 1998)
benzylidene compounds Compounds containing the phch= radical.
(12 Dec 1998)
bephenium compounds <chemical> Analogs or derivatives of bephenium (n,n-dimethyl-n-(2-phenoxyethyl)benzenemethanaminium).
Pharmacological action: antinematodal agent.
(12 Dec 1998)
bicyclo compounds, heterocyclic A class of saturated compounds consisting of two rings only, having two or more atoms in common, containing at least one hetero atom, and that take the name of an open chain hydrocarbon containing the same total number of atoms.
(12 Dec 1998)
boron compounds Inorganic or organic compounds that contain boron as an integral part of the molecule.
(12 Dec 1998)
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