| ¿µ¹® | protein | ÇÑ±Û | ´Ü¹éÁú |
|---|---|---|---|
| ¼³¸í | ź¼Ò, ¼ö¼Ò, »ê¼Ò, Áú¼Ò, ȲÀ» ÇÔÀ¯Çϰí ÀÖ´Â À¯±âÈÇÕ¹°·Î, ¸ðµç ¼¼Æ÷ÀÇ ¿øÇüÁúÀ» ÀÌ·ç°í ÀÖ´Â ±âº» ±¸¼º¹°ÁúÀÌ´Ù. ´Ü¹éÁúÀº ±× ´ÜÀ§ÀÎ ¾Æ¹Ì³ë»êµéÀÌ ÆéƼµå°áÇÕ¿¡ ÀÇÇØ °áÇյǾî ÀÖÀ¸¸ç, º¸Åë 20°³ÀÇ ¾Æ¹Ì³ë»êµéÀÌ ´Ù¸¥ ¼ø¼¿Í Á¶¼ºÀ» °¡Áö°í ¹è¿µÇ¾î, µ¶Æ¯ÇÑ ÇϳªÀÇ ´Ü¹éÁúÀ» Çü¼ºÇÏ°Ô µÈ´Ù. |
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| ¿µ¹® | agonist | ÇÑ±Û | ÀÛ¿ëÁ¦, ÀÛ¿ë±Ù |
|---|---|---|---|
| ¼³¸í | 1. ¼ö¿ëü¿Í °áÇÕÇÏ¿© ÃÖ´ëÀÇ ¾à¸®ÀÛ¿ëÀ» ¹ßÇöÇÏ´Â ÈÇй°ÁúÀ» ¸»ÇÑ´Ù. ¼ö¿ëü¿¡ ƯÀÌÇÏ°Ô Ä£È¼ºÀ» °¡Áö°í ÀÖ´Ù. »ýü ¾È¿¡¼ »ý»êµÇ´Â ³»ÀμºÀÎ °Í°ú »ýü ¹Û¿¡¼ Åõ¿©µÇ´Â ¿ÜÀμºÀÎ °ÍÀÌ ÀÖ´Ù. ºÎºÐ ÀÛ¿ëÁ¦´Â ¼ö¿ëü¿Í °áÇÕÇØµµ 100%ÀÇ ¾à¸®ÀÛ¿ëÀ» ¹ßÇöÇÏÁö´Â ¾ÊÀ¸¸ç ¿ë·®À» Áõ°¡½ÃÄѵµ È¿°ú´Â Ä¿ÁöÁö ¾Ê´Â´Ù. 2. ÇØºÎÇп¡¼´Â ÁÖ°¡ µÇ¾î ¿òÁ÷ÀÌ´Â ±ÙÀ°ÀÇ ¹«¸® |
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| ¿µ¹® | brain death | ÇÑ±Û | ³ú»ç |
|---|---|---|---|
| ¼³¸í | ³ú±â´ÉÀÌ ¿ÏÀüÈ÷ Á¤ÁöµÇ¾î ȸº¹ ºÒ´ÉÇÑ »óÅÂ. ³úÀÇ ±â´É¿¡´Â ´ë³ú¹Ý±¸ÀÇ ±â´É À̿ܿ¡ ³ú°£ÀÇ ±â´Éµµ Æ÷ÇԵȴÙ. ³ú»ç´Â Àΰ£ÀÇ Á×À½°ú °°Àº ¶æÀÌ ¾Æ´Ï°í, º¸ÅëÀº ³ú»ç ´ÙÀ½¿¡ Á×À½ÀÌ ¿Â´Ù. ½ÉÀåÀÌ½Ä ¼ö¼ú¿¡´Â °¡´ÉÇÑ ÇÑ ½Å¼±ÇÑ ½ÉÀåÀÌ ÇÊ¿äÇϱ⠶§¹®¿¡ ½ÉÀå Á¦°øÀÚÀÇ Á×À½À» ³ú»ç·Î ±ÔÁ¤ÇÏ·Á´Â ¿òÁ÷ÀÓÀÌ ÀÖ¾ú´Ù. 1968³â 8¿ù ¼¼°èÀÇ»çȸ ÃÑȸ¿¡¼ äÅÃµÈ Àå±âÀ̽Ŀ¡ °üÇÑ ¼±¾ð(½Ãµå´Ï ¼±¾ð)¿¡¼´Â ¨ç ½ÉÀå Á¦°øÀÚÀÇ Á×À½ÀÇ ÆÇÁ¤Àº ³úÆÄÃøÁ¤»óÀÇ ³úÆÄÀÇ Á¤Áö(³ú»ç)·Î °áÁ¤ÇØ¾ß ÇÑ´Ù. ¨è Á¦°øÀÚÀÇ Á×À½À» È®ÀÎÇϴµ¥ µÎ¸íÀÌ»óÀÇ Àǻ簡 ÀÔÈ¸ÇØ¾ß Çϸç, ³ú»çÀÇ °áÁ¤¿¡ Âü¿©ÇÑ ÀÇ»ç´Â À̽ļö¼ú¿¡ °ü¿©Çؼ´Â ¾È µÈ´Ù°í Çß´Ù. ±×·¯³ª ³úÆÄÃøÁ¤¸¸À¸·Î´Â ³úÁÙ±âÀÇ ±â´ÉÁ¤Áö¸¦ ÆÇÁ¤ÇÒ ¼ö ¾ø°í, ³ú»çÀÇ ÆÇÁ¤µµ Áúº´ÀÇ Á¾·ù³ª Áøµµ¿¡ µû¶ó ±âÁØÀÌ ´Þ¶óÁö¹Ç·Î ÆÇÁ¤±âÁØÀÇ °ËÅä°¡ ÇÊ¿äÇÏ´Ù. ³úÁ¾¾ç-³ú¿Ü»ó-Ç÷ÇàÀå¾Ö µî ³úÁúȯÀÇ Áõ·Ê¿¡¼ º¸¸é ¨ç ±íÀº È¥¼ö, ¨è ¾çÂÊ µ¿°øÀÇ È®´ë ¹× µ¿°øÀÇ ºû¹Ý»ç¿Í °¢¸·¹Ý»çÀÇ ¼Ò½Ç, ¨é È£ÈíÀÇ Á¤Áö, ¨ê ³úÆÄÀÇ ÆòźÈ, ¨ë Ç÷¾ÐÀÇ ±Þ°ÝÇÑ ÀúÇÏ¿Í ±×¿¡ µû¸¥ ÀúÇ÷¾Ð µî ´Ù¼¸ °¡Áö Á¶°ÇÀÌ 6½Ã°£ ÈÄ¿¡µµ µ¿ÀÏÇÑ »óÅ¿¡ ÀÖ´Â °Í µî ¿©¼¸°¡Áö Á¶°ÇÀÌ ÆÇÁ¤ ±âÁØÀÌ µÇ¾ú¾ú´Ù. ÇöÀç´Â °¡Àå °·ÂÇÑ µ¿ÅëÀڱؿ¡ ´ëÇØ¼µµ ÀüÇô ¾Æ¹«·± °¨¼ö¼º°ú ¹ÝÀÀ¼ºÀ» ³ªÅ¸³»Áö ¾Ê´Â 24½Ã°£¿¡ °ÉÄ£ È¥¼ö·Î¼, Àڹ߿ ¶Ç´Â ÀÚ¹ßÈ£ÈíÀÌ ¾ø°í À¯¹ß¹Ý»ç°¡ ¼Ò½ÇµÇ°í ³úÀÇ Àü±âȰµ¿ÀÌ ¾ø¾îÁö´Â ȸº¹ºÒ°¡´ÉÇÑ ÀǽļҽÇÀ̶ó°í Á¤ÀÇÇϰí ÀÖ´Ù. |
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| ¿µ¹® | death | ÇÑ±Û | »ç¸Á, Á×À½, »ç |
|---|---|---|---|
| ¼³¸í | 1. »ý¸íȰµ¿ÀÌ Á¤ÁöµÇ¾î ´Ù½Ã ¿ø»óÅ·Πµ¹¾Æ¿ÀÁö ¾Ê´Â »ý¹°ÀÇ »óÅÂ. »îÀÇ Á¾¸»À» ¸»ÇÑ´Ù. ¿¹¸¦ µé¾î ¾Æ¸Þ¹Ù µîÀÇ ´Ü¼¼Æ÷ »ý¹°¿¡¼´Â 2°³Ã¼·Î ºÐ¿µÉ ¶§°¡ Á×À½À̶ó°í ¸»ÇÒ ¼ö ÀÖÀ»Áö ¸ð¸£³ª ´Ù¼¼Æ÷ »ý¹°¿¡ À־ ¼¼Æ÷ºÐ¿Àº ´Ü¼øÇÑ ¼ºÀåÀÇ ÇÑ °úÁ¤ÀÌ´Ù. »ý¹°Àº »ý½Ä¼¼Æ÷¸¦ ¸Å°³·Î »ý¸íÀ» ¿µ¿øÈ÷ Á¸¼Ó½ÃŰ´Â °ÍÀ̶ó°í º¼ ¼ö ÀÖ´Ù. Àΰ£À» Æ÷ÇÔÇÑ °íµîµ¿¹°¿¡ ÇÑÁ¤ÇÑ´Ù°í Çϸé Á×À½À̶õ ±× °³Ã¼¸¦ ±¸¼ºÇÏ´Â ¸ðµç Á¶Á÷ ¼¼Æ÷ÀÇ »ýȰ±â´ÉÀÇ Á¤Áö¶ó°í ¸»ÇÒ ¼ö ÀÖ´Ù. µû¶ó¼, ±¹ºÎÀûÀÎ ÇÑ ºÎºÐÀÇ »ýȰ±â´ÉÀÇ Á¤Áö¸¸À¸·Î´Â Á×À½À̶ó°í ÇÒ ¼ö ¾ø´Ù. 2. »ç¶÷ÀÌ Á×À½. »ç¶÷ÀÇ Á×À½Àº ³× °³ÀÇ Ãø¸éÀÌ ÀÖ´Ù. Áï ¨ç À°Ã¼Àû Á×À½(biological death), ¨è ½É¸®Àû Á×À½(psychological death), ¨é »çȸÀû Á×À½(social death), ¨ê ¹®ÈÀû Á×À½(culture death)À¸·Î »ý°¢ÇÒ ¼ö ÀÖ´Ù. Àΰ£ÀÇ ÀÏ»ýÀº ´ÜÁö »ý¸íÀÇ ¿¬Àå »Ó ¾Æ´Ï¶ó ÁúÀû Ãø¸é¿¡¼ ½É¸®Àû, »çȸÀû, ¹®ÈÀûÀÎ Ãæ½ÇÇÔÀÌ ÇÊ¿äÇÏ´Ù. ±Ù³â¿¡ ÀÇ·á±â¼úÀÇ ´«ºÎ½Å ¹ß´Þ¿¡ µû¶ó¼ ´õ¿í »ýȰÀÇ ÁúÀÌ Áß¿ä½ÃµÇ°í ÀÖ´Ù. ÀϹÝÀûÀ¸·Î À°Ã¼ÀûÀÎ Á×À½ÀÇ Á¤ÀÇ´Â ¸ðµç »ýü±â´ÉÀÇ ¿µ±¸Àû Á¤Áö. Áï ¨ç Àüü³ú±â´É, ¨è È£Èí°èÀÇ Àڹ߱â´É, ¨é ¼øÈ¯°èÀÇ Àڹ߱â´É, ÀÌ ¸ðµç °ÍÀÇ ºñ°¡¿ªÀûÀ¸·Î Á¤ÁöµÇ¾úÀ½À» ¸»ÇÑ´Ù. |
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| ¿µ¹® | sudden infant death syndrome | ÇÑ±Û | ¿µ¾Æ±Þ»çÁõÈıº |
|---|---|---|---|
| ¼³¸í | ÇÑ »ì ÀÌÇÏÀÇ °Ç°ÇÑ ¾Æ±â°¡ ¾Æ¹«·± Á¶ÁüÀ̳ª ¿øÀÎ ¾øÀÌ °©Àڱ⠻ç¸ÁÇßÀ» °æ¿ì¿¡ ³»¸®´Â Áø´ÜÀÌ´Ù. ÀÌ ÁõÈıºÀº »ýÈÄ 1~4°³¿ù »çÀÌ¿¡ °¡Àå ¸¹ÀÌ ¹ß»ýÇϸç, ´ëºÎºÐ ¹ã 10½Ã¿¡¼ ¿ÀÀü 10½Ã »çÀÌ¿¡ ¹ß»ýÇÑ´Ù. Á¶»êÇϰųª ºÎ¸ð°¡ Èí¿¬ÀÚÀÏ °æ¿ì, 20¼¼ ÀÌÇÏ »ê¸ðÀÇ ÃÊ»ê, ÀÓ½ÅÀü °Ç°°ü¸®¿¡ ¼ÒȦÇÑ »ê¸ð¿¡°Ô¼ ÅÂ¾î³ ¿µ¾Æ¿¡°Ô¼ ¸¹ÀÌ ¹ß»ýÇÑ´Ù. ÀÌ ÁõÈıºÀ¸·Î »ç¸ÁÇÑ ¿µ¾ÆÀÇ ÇüÁ¦ÀÏ °æ¿ì ÀϹÝÀûÀÎ ¿µ¾Æº¸´Ù °É¸± È®·üÀÌ ³ôÀº °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. |
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| IHSS(= HCMP) | Idiopathic Hypertrophic Subaortic Stenosis = Obstructive Idiopathic Hypertrophic Car... |
|---|---|
| ORA | opiate receptor agonist |
| PAA | partial agonist activity; phenylacetic acid; phosphonoacetic acid; physical abilities analysis; plas... |
| SIDS | Sudden Infant Death Syndrome; ¿µ¾Æ µ¹¿¬»ç ÁõÈıº = Crib Death |
| BD | barbital-dependent; barbiturate dependence; base deficit; base of prism down; basophilic degeneratio... |
| FADD | FAS-associated death domain protein |
|---|---|
| DED | death effector domain |
| FADD | Fas Associated Death Domain |
| GRIP1 | Glucocorticoid receptor interacting protein 1 |
| GRIP | Glutamate receptor interacting protein |
| agonist | 1. <anatomy> A prime mover. 2. <pharmacology> A drug that has affinity for and stimulates physiologic activity at cell receptors normally stimulated by naturally occurring substances, thus triggering a biochemical response. (18 Nov 1997) |
|---|---|
| calcium channel agonist | <pharmacology> Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in vascular smooth muscle and/or cardiac muscle cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture. (12 Dec 1998) |
| receptor agonist | A substance that mimics a specificneurotransmitter, is able to attach to that neurotransmitter's receptor and thereby produces the same action that theneurotransmitter usually produces. Drugs are often designed as receptor agonists to treat a variety of diseases and disorders whenthe original chemical substance is missing or depleted. (22 May 1997) |
| mixed opioid agonist-antagonist | <pharmacology> A compound that has an affinity for two or more types of opioid receptors and blocks opioid effects on one receptor type while producing opioid effects on a second receptor type. (13 Nov 1997) |
| muscarinic agonist | Drugs that bind to and activate muscarinic cholinergic receptors (receptors, muscarinic). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate. (12 Dec 1998) |
| histamine agonist | Drugs that bind to and activate histamine receptors. Although they have been suggested for a variety of clinical applications histamine agonists have so far been more widely used in research than therapeutically. (12 Dec 1998) |
| opioid agonist | <pharmacology> Any morphine-like compound that produces bodily effects including pain relief, sedation, constipation and respiratory depression. (16 Dec 1997) |
| opioid partial agonist | <pharmacology> A compound that has an affinity for and stimulates physiologic activity at the same cell receptors as opioid agonists but that produces only a partial (i.e., submaximal) bodily response. (16 Dec 1997) |
| LH and RH agonist | <pharmacology> Particular medications that act as potent inhibitors of gonadotrophin (testosterone) secretion. They act to inhibit the production of testosterone through a feedback mechanism on the pituitary gland. LH and RH agonists are useful in the treatment of prostate cancer. (14 Oct 1997) |
| apple domain | <molecular biology> A consensus sequence, composed of 90 amino acids including 6 cysteines, that forms a characteristic, vaguely apple shaped, pattern via disulphide bridges. Shared by plasma kallikrein and coagulation factor XI, both serine proteases. (18 Nov 1997) |
| carboxy-terminal domain kinase | <enzyme> Protein kinase that phosphorylates the c-terminal repeat domain of the largest subunit of RNA polymerase II at serine residues Registry number: EC 2.7.1.- Synonym: ctd kinase, hs-ctd kinase, tfiih-associated ctd kinase (26 Jun 1999) |
| paired box domain | <molecular biology> Conserved domain of 128 amino acids, found in several developmentally regulated proteins in Drosophila (for example paired, gooseberry, Pox), mouse and human (for example Pax, HuP1, HuP48). (18 Nov 1997) |
| POU domain | <molecular biology> A conserved protein domain of around 150 amino acids, composed of a 20 amino acid homeobox domain and a larger POU specific domain and so is the target of some transcription factors. Named POU (Pit Oct Unc) after 3 such proteins: Pit 1 regulates expression of certain pituitary genes, Oct 1 and 2, that bind an octamer sequence in the promoters of histone H2A and some immunoglobulin genes and Unc 86, involved in nematode sensory neuron development. (31 Dec 1997) |
| SH3 domain-containing proline-rich kinase | <enzyme> A protein kinase which both phosphorylates ser and thr residues and has an sh3 domain; contains 847 amino acid residues; mol mass 92,688 da; genbank u07747 Registry number: EC 2.7.10.- Synonym: src-homology 3 domain-containing proline-rich kinase, sprk protein, sprk gene product (26 Jun 1999) |
| dinucleotide domain | A structural domain in certain proteins that binds NAD+ or NADP+. Synonym: dinucleotide domain. (05 Mar 2000) |
Synonyms : Truncated Bid Protein
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