| B-cell | <haematology, immunology> A type of lymphocyte normally involved in the production of antibodies to combat infection. It is a precursor to a plasma cell. During infections, individual B-cell clones multiply and are transformed into plasma cells, which produce large amounts of antibodies against a particular antigen on a foreign microbe. This transformation occurs through interaction with the appropriate CD4 T-helper cells. (09 Oct 1997) |
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| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| B-cell differentiating factor | <cytokine> A soluble cytokine factor produced by activated T-lymphocytes that promotes antibody production by causing proliferation and differentiation of B-cells. Interleukin-4 induces the expression of class II major histocompatibility complex and fc receptors on B-cells. It also acts on T-lymphocytes, mast cell lines, and several other haematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. Acronym: IL-4 (12 Dec 1998) |
| B-cell differentiation/growth factors | Various substances, usually obtained from the supernatant of T-cell cultures, such as interleukin 4, 5, and 6. These substances are necessary for B-cell growth, maturation, and differentiation into plasma cells or B memory cells. (05 Mar 2000) |
| B-cell leukaemia | A test which detects the presence of antigens on the surface of B lymphocytes. These antigens can indicate the presence of leukaemia. most often this is used to detect and differentiate chronic lymphocytic leukaemia from acute lymphocytic leukaemia. Origin: Gr. Haima = blood (27 Sep 1997) |
| B-cell stimulatory factor 2 | <cytokine> A cytokine that stimulates the growth and differentiation of human B-cells and is also a growth factor for hybridomas and plasmacytomas. It is produced by many different cells including T-cells, monocytes, and fibroblasts. A single chain 25 kD cytokine originally described as a pre B-cell growth factor, now known to have effects on a number of other cells including T-cells which are also stimulated to proliferate. An inducer of acute phase proteins and a colony-stimulating factor acting on mouse bone marrow. Acronym: IL-6 (12 Dec 1998) |
| B-cells | A type of white blood cell. Many B-cells mature into plasma cells, which can produce antibody proteins necessary to fight off infections, such as viruses. (12 Dec 1998) |
Synonyms : B Cell Activating Factor, B Lymphocyte Stimulator, B-Lymphocyte Activating Factor, BLyS Protein, CD257 Antigen, TALL-1 Protein, THANK Protein, TNF Superfamily, Member 13b, TNF and APOL-Related Leukocyte Expressed Ligand 1, Activating Factor, B-Cell
Synonyms : BAFF Receptor, BR3 B-Cell Activation Factor Receptor, CD268 Antigen, Antigen, CD268, B Cell Activation Factor Receptor, BR3 B Cell Activation Factor Receptor, Receptor, BAFF
Synonyms : B Cell Maturation Protein A, BCMA Protein, Tumor Necrosis Factor Receptor Superfamily, Member 17, B Cell Maturation Antigen, Maturation Antigen, B-Cell
Synonyms : B Cell-Specific Transcription Factor, Early B Cell-Specific Binding Protein-1, PAX5 Transcription Factor, Pax5A Transcription Factor, B Cell Specific Activator Protein, B Cell Specific Transcription Factor, Early B Cell Specific Binding Protein 1
| B-cell l. |
any in a large group of non-Hodgkin's lymphomas characterized by malignant transformation of the B lymphocytes; among the many B-cell lymphomas are Burkitt's l., l. cutis, follicular center cell l., and small B-cell l.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| B-cell monocytoid l. |
a low-grade marginal zone lymphoma in which cells resemble those of hairy cell leukemia.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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