| ¿µ¹® | bronchial asthma | ÇÑ±Û | ±â°üÁöõ½Ä |
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| ¿µ¹® | gene | ÇÑ±Û | À¯ÀüÀÚ |
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| ¿µ¹® | gene therapy | ÇÑ±Û | À¯ÀüÀÚ¿ä¹ý |
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| ¼³¸í | À¯Àüº´À» Ä¡·áÇÒ ¸ñÀûÀ¸·Î, Á¤»óÀûÀ¸·Î ±â´ÉÇÏ´Â ´ÜÀÏÀ¯ÀüÀÚ È¤Àº º¹¼öÀ¯ÀüÀÚ¸¦ ¾î¶² ±â¿ø¿¡¼ ¾ò¾î³»¾î »ý¼¼Æ÷¿¡ µµÀÔÇÏ´Â °Í. À¯Àü¹°ÁúÀº À¯ÀüÀÚ»ðÀÔ Á¶ÀÛ¿¡ ÀÇÇØ ¼ö¿ë¼¼Æ÷¿¡·Î µµÀԵȴÙ. Áï, À¯ÀüÀÚ¸¦ ³¢¿ö ³ÖÀº »õ·Î¿î ¼¼Æ÷¸¦ »ç¿ëÇÏ´Â Ä¡·á·Î¼ 1980³â ¹Ì±¹ÀÇ ÇÐÀÚ°¡ ÁöÁßÇØºóÇ÷ȯÀÚ¿¡°Ô °ÇàÇÏ¿© ºñÆÇÀ» ¹Þ¾ÒÁö¸¸, ¹Ì±¹ ±¹¸³º¸°Ç¿¬±¸¼Ò´Â 1990³â 9¿ù ¾Æµ¥³ë½Å µ¥¾Æ¹Ì³ª¾ÆÁ¦(adenosine deaminase, ADA) °áÇÌÁõ ȯÀÚÀÇ ¸²ÇÁ±¸¿¡ ADA À¯ÀüÀÚ¸¦ ³¢¿ö ³Ö´Â Ä¡·á¸¦ ½ÃÀÛÇÑ ÀÌ·¡ ÇöÀç´Â ¾ÏÀ» Æ÷ÇÔÇÑ ¸¹Àº Áúº´µéÀ» Ä¡·áÇÏ´Â ¸ñÀûÀ¸·Î ¾²ÀδÙ. |
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| ¿µ¹® | asthma | ÇÑ±Û | õ½Ä |
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| ¼³¸í | õ½ÄÀ̶õ ¿©·¯ °¡Áö Àڱؿ¡ ´ëÇØ¼ ±â°üÁö°¡ °ú¹ÎÇÑ ¹ÝÀÀÀ¸·Î »ý±â´Â ±â°üÁöÀÇ °¡¿ªÀûÀÎ Æó¼â¸¦ ÀǹÌÇÑ´Ù. Áï Á¤»óÀο¡°Ô¼´Â ¹ÝÀÀÀÌ ¾ø´Â Àڱؿ¡ ´ëÇØ¼ ±â°üÁöÀÇ Æó¼â°¡ »ý±â°í ±× ÀÚ±ØÀÌ ¾øÀ» °æ¿ì¿¡´Â ±â°üÁöÀÇ Æó¼â°¡ ¼Ò½ÇÇÏ´Â ÁúȯÀ» ¸»ÇÑ´Ù. õ½ÄÀÇ ¿øÀÎÀº ÁÖ·Î Á¦1Çü °ú¹Î°¨¹ÝÀÀ¿¡ ÀÇÇÑ´Ù. Á¦1Çü °ú¹Î°¨¹ÝÀÀÀ̶õ ¿Ü°èÀÇ ¹°Áú¿¡ ´ëÇÑ ¸é¿ª ¹ÝÀÀÀÌ Áö³ªÄ¡°Ô Ç×ÁøµÇ¾î ÀÖ´Â º´ÀûÀÎ »óŸ¦ ¸»ÇÑ´Ù. ¸é¿ªÀ̶õ ¿ÜºÎ¹°Áú¿¡ ´ëÇÑ ¹æ¾î¸¦ ¸ñÀûÀ¸·Î ÇÏ´Â ¼¼Æ÷µéÀÇ È°µ¿À» ÀǹÌÇÏ¸ç ¿©±â¿¡´Â Ç×üÀÇ Çü¼º, ¼¼Æ÷µéÀÇ Å½½ÄÀÛ¿ë(¿ÜºÎ¿¡¼ µé¾î¿Â ¹°ÁúÀ» ¸é¿ª±â´ÉÀ» ÇÏ´Â ¼¼Æ÷°¡ Àâ¾Æ¸Ô´Â °Í) µîÀÌ Æ÷ÇԵȴÙ. Ç×üÀÇ Çü¼ºÀº ¿ÜºÎ·ÎºÎÅÍ µé¾î¿Â ¹°ÁúÀ» ¿ì¼± ´ë½Ä¼¼Æ÷ µîÀÌ Æ÷½ÄÀ» Çϰí À̰Ϳ¡ ´ëÇÑ Á¤º¸¸¦ T-¼¼Æ÷¿¡°Ô Àü´ÞÇϰí T-¼¼Æ÷´Â ÀÌ Á¤º¸¸¦ ó¸®ÇÏ¿© Áý¾àµÈ Á¤º¸¸¦ B-¼¼Æ÷¿¡°Ô Àü´ÞÇϸç ÀÌ ¼¼Æ÷·Î ÇÏ¿©±Ý ±× ¹°Áú¿¡ ´ëÇÑ Ç×ü¸¦ »ý¼ºÇÏ°Ô ÇÑ´Ù. Ç×ü´Â ¿ÜºÎÀÇ ¹°Áú°ú Á¤È®È÷ °áÇÕÇÏ¿© ¿ÜºÎ ¹°ÁúÀÇ È°¼ºÀ» ¾ø¾Ö´Â ¹°ÁúÀÌ´Ù. ÀÌ·¸°Ô Çü¼ºµÈ Ç×ü Áß¿¡¼ IgE¶ó´Â °ÍÀÌ Àִµ¥ À̰ÍÀº ºñ¸¸¼¼Æ÷¶ó´Â ¼¼Æ÷ÀÇ Ç¥¸é¿¡ ºÎÂøµÇ¾î ÀÖ´Ù. ¸¸¾à ÀÌ IgE¿¡ ºÎÂøµÉ ¼ö ÀÖ´Â, Áï ÀÌ¹Ì Ç×ü(IgE)°¡ Çü¼ºµÈ(ÀÌ·¸°Ô µÇ±âÀ§Çؼ´Â ±× ¹°ÁúÀÌ ÀÌÀü¿¡ ÇÑ ¹ø ¸ö¼Ó¿¡ µé¾î¿Ô¾î¾ß ÇÑ´Ù) ¹°ÁúÀÌ ´Ù½Ã ü³»¿¡ µé¾î¿À°Ô µÇ¸é IgE°¡ ºÎÂøµÈ ºñ¸¸¼¼Æ÷¿¡¼ È÷½ºÅ¸¹Î°ú ¿©·¯ °¡Áö ´Ù¸¥ ¹°ÁúÀÌ ³ª¿À°Ô µÇ¸ç, ÀÌ ¹°ÁúµéÀº ´Ù¸¥ ¿°Áõ¿¡ °ü°èÇÏ´Â ¼¼Æ÷µéÀ» ¸ðÀ¸°Ô µÇ°í, ±â°üÁöºÐºñ¹°ÀÇ ºÐºñ¸¦ Áõ°¡½ÃŰ°í ¶Ç ±â°üÁö¿¡ ÀÖ´Â ±ÙÀ°¼¼Æ÷¸¦ Á÷Á¢, °£Á¢À¸·Î ÀÚ±Ø(±³°¨½Å°æ°èÀÇ ÀÚ±ØÀ» ÅëÇØ¼ °£Á¢ÀûÀ¸·Î ±â°üÁöÀÇ ±ÙÀ°¼¼Æ÷¸¦ ÀÚ±Ø)ÇÏ¿© ¼öÃàÇÏ°Ô ÇÑ´Ù. ÀÌ·Î ÀÎÇÏ¿© ±â°üÁöÀÇ ¿°Áõ°ú ±â°üÁöÀÇ ¼öÃàÀÌ À¯µµµÈ´Ù. ±â°üÁöÀÇ Àڱؿ¡ ´ëÇÑ °ú¹Î¼ºÀ̶õ ÀÌ·± ÀÏ·ÃÀÇ °úÁ¤¿¡ ÀÇÇØ¼ ÀϾÙ. IgE¿¡ ºÎÂøµÉ ¼ö ÀÖ´Â ¹°ÁúÀÌ »ç¶óÁø °æ¿ì¿¡´Â ÀÌ·± ÀÏ·ÃÀÇ °úÁ¤ÀÌ ÀϾÁö ¾Ê°Ô µÇ°í ±â°üÁöÀÇ ¿°ÁõÀ̳ª ±â°üÁöÀÇ ¼öÃà°°Àº Áõ»óÀº »ç¶óÁö°Ô µÈ´Ù. õ½ÄÀ» °¡¿ª¼º ±âµµÆó¼â¶ó°í ºÎ¸£´Â ÀÌÀ¯°¡ ¹Ù·Î ¿©±â¿¡ ÀÖ´Ù. |
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| MSS | Marshall-Smith syndrome; massage; Medical Superintendents' Society; Medicare Statistical System; men... |
|---|---|
| ASA | acetylsalicylic acid; active systemic anaphylaxis; Adams-Stokes attack; American Society of Anesthes... |
| MSSG | multiple sclerosis susceptibility gene |
| CB3S | Coxsackie B3 virus susceptibility |
| cm | magnetic susceptibility |
| DSC | Dynamic susceptibility contrast |
|---|---|
| HGSHS:A | Harvard Group Scale of Hypnotic Susceptibility, Form A |
| MHS | Malignant hyperthermia susceptibility |
| S | R)/susceptibility |
| SHSS:C | Standford Hypnotic Susceptibility Scale, Form C |
| BRCA1 breast cancer susceptibility gene | This mutated (changed) version of the BRCA1 gene makes a person susceptible to developing breast cancer. (12 Dec 1998) |
|---|---|
| cancer susceptibility gene | tumour suppressor gene |
| breast cancer susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer, breast, susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| genes, breast cancer susceptibility | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. Howeverm, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. See related entries to: BRCA1; BRCA2; Breast cancer, familial. (12 Dec 1998) |
| colourimetric caries susceptibility test | A colourimetric test for determining dental caries activity or susceptibility based on the rate of acid production by acidogenic oral microorganisms (e.g., lactobacillus) in a glucose medium, using bromcresol green as the indicator, and producing a colour change from green to yellow. Synonym: colourimetric caries susceptibility test. (05 Mar 2000) |
| susceptibility | Origin: Cf. F. Susceptibilite. 1. The state or quality of being susceptible; the capability of receiving impressions, or of being affected. 2. Specifically, capacity for deep feeling or emotional excitement; sensibility, in its broadest acceptation; impressibility; sensitiveness. <physics> Magnetic susceptibility, the intensity of magnetization of a body placed in a uniform megnetic field of unit strength. Synonym: Capability, sensibility, feeling, emotion. Source: Websters Dictionary (01 Mar 1998) |
| susceptibility testing | The determination of the ability of an antibiotic to kill or inhibit the growth of bacteria. (05 Mar 2000) |
| disease susceptibility | A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases. (12 Dec 1998) |
| allergic asthma | <chest medicine> A disease process that is characterised by paradoxical narrowing of the bronchi (lung passageways) making breathing difficult. Treatment includes bronchodilators which are given orally or delivered as an aerosol (inhaled). Corticosteroids are reserved for more difficult cases. Symptoms include wheezing, difficulty breathing (particularly exhaling air) and tightness in the chest. Factors which can exacerbate asthma include rapid changes in temperature or humidity, allergies, upper respiratory infections, exercise, stress or smoke (cigarette). See: status asthmaticus. (27 Sep 1997) |
| asthma | <chest medicine> A disease process that is characterised by paradoxical narrowing of the bronchi (lung passageways) making breathing difficult. Treatment includes bronchodilators which are given orally or delivered as an aerosol (inhaled). Corticosteroids are reserved for more difficult cases. Symptoms include wheezing, difficulty breathing (particularly exhaling air) and tightness in the chest. Factors which can exacerbate asthma include rapid changes in temperature or humidity, allergies, upper respiratory infections, exercise, stress or smoke (cigarette). See: status asthmaticus. (27 Sep 1997) |
| asthma crystals | Crystal's in the shape of elongated double pyramids, formed from eosinophils, found in the sputum in bronchial asthma and in other exudates or transudates containing eosinophils. Synonym: asthma crystals, Charcot-Neumann crystals, Charcot-Robin crystals, Leyden's crystals. (05 Mar 2000) |
| asthma, exercise-induced | Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. Inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it). (12 Dec 1998) |
| asthma-weed | Synonym: lobelia. Synonym: Euphorbia pilulifera. (05 Mar 2000) |
| atopic asthma | Bronchial asthma due to atopy. (05 Mar 2000) |
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