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MMP matrix metalloproteinase; muscle mechanical power
MMPI matrix metalloproteinase specific for collagen type I; Minnesota Multiphasic Personality Inventory
PUMP putative metalloproteinase
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A.f. Aspergillus fumigatus
MMP-9 B/matrix metalloproteinase-9
EMMPRIN Extracellular matrix metalloproteinase inducer
MMP-3 MATRIX METALLOPROTEINASE-3
MMP-2 Matrix Metalloproteinase-2
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CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
Aspergillus fumigatus metalloproteinase <enzyme> Mol mass 82 kD; pi 5.6; hydrolyzes phenylazobenzyloxycarbonyl-pro-leu-gly-pro-arg and cleaves native rat type I collagen
Registry number: EC 3.4.24.-
Synonym: a. Fumigatus metalloproteinase, af-mep
(26 Jun 1999)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
aspergillus fumigatus A species of imperfect fungi from which the antibiotic fumigatin is obtained. Its spores may cause respiratory infection in birds and mammals.
(12 Dec 1998)
BaP1 metalloproteinase <enzyme> From bothrops asper venom; causes haemorrhage at site of venom injection and systemically in different organs
Registry number: EC 3.4.24.-
(26 Jun 1999)
membrane-type 3 matrix metalloproteinase <enzyme> Sm3 is a soluble form of mt3-mmp, probably an alternatively sliced variant.
Registry number: EC 3.4.24.-
Synonym: mt3-mmp, sm3-mmp
(26 Jun 1999)
membrane-type 4 matrix metalloproteinase <enzyme> Cloned from breast carcinoma.
Registry number: EC 3.4.24.-
Synonym: mt4-mmp, mmp-17 gene product, mmp-17
(26 Jun 1999)
membrane-type matrix metalloproteinase <enzyme> Activates gelatinase a; isolated from a human placenta cdna gene library; contains a transmembrane domain; do not use for any other numbered matrix metalloproteinases; genbank d26512
Registry number: EC 3.4.24.-
Synonym: mt-mmp, mmp-x1 protein, matrix metalloproteinase, membrane-type, mmp14 gene product, mmp-14 gene product, mt1-mmp, matrix metalloproteinase 14, mt2-mmp, mmp15 gene product, mmp16 gene product
(26 Jun 1999)
haemorrhagic metalloproteinase <enzyme> Extracted from vipera berus berus venom; hydrolyzes casein, fibrinogen and splits the insulin b chain at positions ala(14)-leu(15), tyr(16)-leu(17), his(10)-leu(11); digests alpha chain of fibrinogen
Registry number: EC 3.4.24.-
(26 Jun 1999)
Xolloid metalloproteinase <enzyme> Tolloid-like protein from xenopus with development-regulating activity; acts as a ventralizing agent that mimics low doses of bone morphogenetic protein-4
Registry number: EC 3.4.24.-
Synonym: xolloid gene product
(26 Jun 1999)
S. marcescens minor metalloproteinase <enzyme> Precursor protein consists of 352 amino acids, mw 38.479 kD from serratia marcescens; mature protein consists of 300 amino acids mw 32.515 kD with optimal activity at pH 8.0 and 50c; do not confuse with smp protein, a membrane protein from E coli
Registry number: EC 3.4.24.-
Synonym: smp proteinase
(26 Jun 1999)
Streptococcus faecalis metalloproteinase <enzyme> Bacterial metalloproteinase from streptococcus faecalis
Registry number: EC 3.4.24.-
Synonym: streptococcus faecalis metalloendopeptidase, metalloproteinase (streptococcus faecalis), sf-metalloproteinase
(26 Jun 1999)
tissue-inhibitor of metalloproteinase-1 <chemical> A member of the family of tissue inhibitor of metalloproteinases. It is a n-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumour invasion in vitro.
Pharmacological action: antineoplastic agent, protease inhibitors.
(12 Dec 1998)
tissue inhibitor-of metalloproteinase-2 <chemical> A member of the family of tissue inhibitor of metalloproteinases. It is a 21 kD nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase a by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of timp-2 has been shown to inhibit invasive and metastatic activity of tumour cells and decrease tumour growth in vivo.
Pharmacological action: antineoplastic agent, protease inhibitors.
(12 Dec 1998)
tissue inhibitor of-metalloproteinase-3 <chemical> A member of the family of tissue inhibitor of metalloproteinases. It is a 21 kD, nonglycosylated protein. Timp-3 does not show a high degree of structural similarity unlike timp-1 and timp-2 which are structurally similar. However, it does possess a high degree of structural similarity with that of chicken timp-3 (chimp-3). Human timp-3 is of particular concern because of its potential role in cancer, arthritis, and eye diseases.
Pharmacological action: antineoplastic agent, protease inhibitors.
(12 Dec 1998)
tissue inhibitors of metalloproteinase <cell biology> Family of proteins of around 200 residues that can inhibit metalloproteinases, for example collagenase, by binding to them.
(18 Nov 1997)
Aspergillus <fungus> A genus of common ascomycete fungi found in soil. Industrially important in production of organic acids and a popular fungus for genetic study (especially. A. Niger).
(18 Nov 1997)
Aspergillus acid proteinase <enzyme> Included in the group of microbial carboxyl proteinases EC 3.4.23.6; has been sequenced; genbank d87681
Registry number: EC 3.4.23.-
Synonym: apfap, aspergillus fumigatus acid proteinase, aspergillus niger acid proteinase, aspergillus awamori acid proteinase
(26 Jun 1999)
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