| ¿µ¹® | protein | ÇÑ±Û | ´Ü¹éÁú |
|---|---|---|---|
| ¼³¸í | ź¼Ò, ¼ö¼Ò, »ê¼Ò, Áú¼Ò, ȲÀ» ÇÔÀ¯Çϰí ÀÖ´Â À¯±âÈÇÕ¹°·Î, ¸ðµç ¼¼Æ÷ÀÇ ¿øÇüÁúÀ» ÀÌ·ç°í ÀÖ´Â ±âº» ±¸¼º¹°ÁúÀÌ´Ù. ´Ü¹éÁúÀº ±× ´ÜÀ§ÀÎ ¾Æ¹Ì³ë»êµéÀÌ ÆéƼµå°áÇÕ¿¡ ÀÇÇØ °áÇյǾî ÀÖÀ¸¸ç, º¸Åë 20°³ÀÇ ¾Æ¹Ì³ë»êµéÀÌ ´Ù¸¥ ¼ø¼¿Í Á¶¼ºÀ» °¡Áö°í ¹è¿µÇ¾î, µ¶Æ¯ÇÑ ÇϳªÀÇ ´Ü¹éÁúÀ» Çü¼ºÇÏ°Ô µÈ´Ù. |
||
| KAF | conglutinogen-activating factor; killer-assisting factor; kinase activating factor |
|---|---|
| LAF | laminar air flow; Latin American female; leukocyte-activating factor; lymphocyte-activating factor |
| PAF | paroxysmal atrial fibrillation; peroxisomal assembly factor; phosphodiesterase-activating factor; pl... |
| RAS | rapid atrial stimulation; recurrent aphthous stomatitis; reflex activating stimulus; reliability, av... |
| GAP | D-glyceraldehyde-3-phosphate; growth associated protein; guanosine triphosphatase-activating protein... |
| AA | Arachidonate |
|---|---|
| FLAP | 5-Lipoxygenase activating protein |
| AP-1 | Activating protein-1 |
| GAP | GTP-ase-activating protein |
| GAP | Guanosine triphosphatase activating protein |
| GTPase activating protein | <molecular biology> Originally purified as a 125 kD protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (PDGF R, EGF R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to GAP. GAP has both SH2 and SH3 domains. Another example is sar 1 (from yeast). (18 Nov 1997) |
|---|---|
| neutrophil activating protein | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| JNK-activating protein kinase | <enzyme> A dual specificity kinase that activates jun kinases and p38-mpk2; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: jnk kinase, jnkk, hemipterous protein, hep protein, jun amino-terminal kinase kinase, jn kinase kinase, hep gene product (26 Jun 1999) |
| arachidonate | <biochemistry> An essential unsaturated fatty acid that humans use to synthesise regulatory molecules such as prostaglandins and thromboxanes. It is found in fatty animal tissue such as egg yolk and liver. (09 Oct 1997) |
| arachidonate 12-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-hpete) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-hete). The 12-hydroperoxides are preferentially formed in platelets. Chemical name: Arachidonate:oxygen 12-oxidoreductase Registry number: EC 1.13.11.31 (12 Dec 1998) |
| arachidonate 15-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-hpete) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-hete). The 15-hydroperoxides are preferentially formed in neutrophils and lymphocytes. Chemical name: Arachidonate:oxygen 15-oxidoreductase Registry number: EC 1.13.11.33 (12 Dec 1998) |
| arachidonate 5-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-hpete) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-hete). The 5-hydroperoxides are preferentially formed in leukocytes. Chemical name: Arachidonate:oxygen 5-oxidoreductase Registry number: EC 1.13.11.34 (12 Dec 1998) |
| arachidonate 8-lipoxygenase | <enzyme> From sea whip coral plexaura homomalla; catalyses the conversion of arachidonic acid to a cyclised prostanoid with a pga ring and the same side chains as the parent arachidonate Registry number: EC 1.13.11.40 Synonym: 8(r)-lipoxygenase, 8-lipoxygenase (26 Jun 1999) |
| arachidonate epoxygenase | <enzyme> Requires cytochrome p-450; uses NADPH and oxygen; forms 5,6-,8,9-11,12- and 14,15-cis-epoxyeicosatrienoic acids; p4502caa is the form isolated from rabbit renal cortex Registry number: EC 1.14.13.- Synonym: NADPH-dependent arachidonic acid epoxygenase, cytochrome p-450 epoxygenase, cytochrome p-450 arachidonate oxygenase, cyp2j2, cyp2caa, cytochrome p-450 2caa (26 Jun 1999) |
| arachidonate lipoxygenases | <enzyme> Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates (hpetes). These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids (hetes). The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. Registry number: EC 1.13.11.- (12 Dec 1998) |
| arachidonate monooxygenase | <enzyme> Nadph-dependent enzyme from renal cortex; not inhibited by cyclooxygenase inhibitors; forms 19-hydroxyarachidonate, 20-hydroxyarachidonate, 19-ketoarachidonate and a dicarboxylic acid Registry number: EC 1.14.13.- (26 Jun 1999) |
| acetyl-activating enzyme | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acyl-activating enzyme | <enzyme> Fatty acid thiokinase (long-chain), a ligase forming acyl-CoA, AMP, and pyrophosphate from long-chain fatty acids, ATP, and coenzyme A. Activity is independent of phosphatidylcholine Registry number: EC 6.2.1.3 Synonym: acyl-activating enzyme, dodecanoyl-CoA synthetase, fatty acid thiokinase (long chain), acid-coenzyme a ligase, fatty acid-CoA ligase, acyl-CoA synthetase, acyl-CoA ligase, coash ligase, ciprofibroyl-CoA synthetase, pristanoyl-CoA synthetase, palmityl CoA synthetase, palmitoyl CoA synthetase, palmitoyl CoA ligase, fatty acyl-CoA synthetase, very long chain fatty acid acyl-CoA synthetase, vlcfa acyl-CoA synthetase, nafenopin-CoA ligase, palmitoyl-CoA synthase, faa2 gene product, faa2p protein, vlacs enzyme (26 Jun 1999) |
| amino acid activating enzyme | <enzyme> Enzymes catalyzing the formation of a specific aminoacyl-tRNA from an amino acid and adenosine 5'-triphosphate with the concomitant formation of adenosine 5'-monophosphate and pyrophosphate. Synonym: amino acid activating enzyme, aminoacyl-tRNA ligases. (05 Mar 2000) |
| anionic neutrophil activating peptide | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
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