| 영문 | apoptosis | 한글 | 세포자멸사, 아포프토시스 |
|---|---|---|---|
| 설명 | 합목적적으로 발현되는 프로그램된 세포사를 말한다. 종래에는 세포사란 괴사 즉 화상 등으로 인하여 한무리의 세포가 죽는 것이라 이해되었으나 1972년 Kerr, Wylliie, Currie의 세 병리학자가 형태적으로 명백하게 다른 또 하나의 세포사를 발견하고 이를 아포푸토시스라고 정의했다. 그 뒤의 연구를 통해 발생단계에서 어느 특정세포가 일정시기, 장소, 순서에 의해죽어감으로써 정상적인 발생이 완료하는 것으로 알려졌으며 특별히 프로그램 세포라 부르는 때도 있다. 또한 가슴샘을 중심으로 하는 면역계의 발달과정에서도 이 세포사는 매우 중요한 역할을 한다는 점, 여러 가지 병과의 관련에 있어서 유전자 수준의 해석을 통한 암관련 유전자, 증식유전자 등과의 복잡한 관련도 알려져 있다. 형태적으로 괴사는 세포전체나 사립체가 서서히 팽창되고 세포질의 변화가 선행되며 최종적으로 세포막의 파괴가 일어나는데 비해, 세포자멸사에서는 DNA의 단편화가 선행되고 그 결과 염색질이 핵막주변에 응집하여 핵농축, 핵용해가 일어나며 거의 동시에 세포의 축소라든가 융모 등의 소실되고 결국 세포 전체가 막에 쌓인 크고 작은 세포자멸사 소체로 단편화되고 최종적으로 비염증적으로 큰포식세포에 탐식된다. 세포자멸사는 괴사와 대립적으로 이해되어 왔지만 최근 들어 이들 두가지 세포죽음의 형태의 공통점도 많이 부각되고 있다. |
||
| 영문 | serum proteins | 한글 | 혈청단백 |
|---|---|---|---|
| 설명 | 혈청에 있는 단백질들을 총칭하는 말로, 면역글로불린(면역현상에 관여하는 항체를 형성함), 알부민, 보체 및 응고인자와 여러 효소들이 이에 속한다. |
||
| ARP | absolute refractory period; American Registry of Pathologists; anticipated recovery path; apolipopro... |
|---|---|
| PBPs | Penicillin-Binding Proteins |
| PVM | pneumonia virus of mice; proteins, vitamins, and minerals |
| RPSP | reference preparation for serum proteins |
| FRP | Follicle Regulatory Protein |
| G-proteins | GTP)-binding regulatory proteins |
|---|---|
| G-proteins | Guanine nucleotide-binding regulatory proteins |
| G proteins | GIP-binding proteins |
| G proteins | reglatory proteins |
| SIRP | Signal-regulatory proteins |
| apoptosis | <cell biology> Programmed cell death as signalled by the nuclei in normally functioning human and animal cells when age or state of cell health and condition dictates. An active process requiring metabolic activity by the dying cell, often characterised by cleavage of the DNA into fragments that give a so called laddering pattern on gels. Cells that die by apoptosis do not usually elicit the inflammatory responses that are associated with necrosis, though the reasons are not clear. Cancerous cells, however, are unable to experience the normal cell transduction or apoptosis-driven natural cell death process. See: ced mutant, bcl. (18 Nov 1997) |
|---|---|
| viral regulatory proteins | Proteins which regulate the rate of transcription of viral structural genes. (12 Dec 1998) |
| gene regulatory protein | <molecular biology> Any protein that interacts with DNA sequences of a gene and controls its transcription. (18 Nov 1997) |
| region, regulatory | See: Regulatory sequence. (12 Dec 1998) |
| regulatory albuminuria | Transitory albuminuria occurring after unusual physical exertion. (05 Mar 2000) |
| regulatory cell proliferation kinase | <enzyme> Involved in mitosis regulation; has characteristics of serine/threonine and tyrosine kinases; isolated from saccharomyces cerevisiae; genbank l08909 Registry number: EC 2.7.1.- Synonym: rpk1 protein, rpk1 gene product (26 Jun 1999) |
| regulatory enzyme | <biochemistry> An enzyme that regulatescertain functions due to its ability to undergoa change in its catalytic activity through modification of its structure. (09 Oct 1997) |
| regulatory gene | A gene that codes for a repressor protein. (09 Oct 1997) |
| regulatory region | <molecular biology> A DNA base sequence that controls gene expression. (14 Oct 1997) |
| regulatory regions or sequences | A DNA base sequence that controls gene expression. (05 Mar 2000) |
| regulatory sequence | <molecular biology> DNA sequence to which regulatory molecules such as promotors or enhancers bind, thereby altering the expression of the adjacent gene. (18 Nov 1997) |
| regulatory sequences, nucleic acid | DNA sequences involved in regulating the expression of other genes. (12 Dec 1998) |
| regulatory T-cell | <immunology> Vague term for any class of T lymphocyte not directly involved in the effector side of immunity, but involved in controlling responses and actions of other cells, especially T helper and T suppressor cells. (18 Nov 1997) |
| myogenic regulatory factors | A family of muscle-specific transcription factors which bind to DNA in control regions and thus regulate myogenesis. All members of this family contain a conserved helix-loop-helix motif which is homologous to the myc family proteins. These factors are only found in skeletal muscle. Members include the myod protein (myod protein), myogenin, myf-5, and myf-6 (also called mrf4 or herculin). (12 Dec 1998) |
| public utility regulatory policies act | (PURPA) A federal law requiring a utility to buy the power produced by a qualifying facility at a price equal to that which the utility would otherwise pay if it were to build its own power plant or buy power from another source. (05 Dec 1998) |
Synonyms : Apoptosis Inducing Proteins, Apoptosis Inhibiting Proteins, Death Factors (Apoptosis), Programmed Cell Death Proteins, Survival Factors (Apoptosis), Regulatory Proteins, Apoptosis
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|