| 영문 | Alzheimer's disease | 한글 | 알츠하이머병 |
|---|---|---|---|
| 설명 | 퇴행성 뇌병. 노인에서의 치매의 원인 중 가장 흔한 형태이다. 병리조직학적으로는 뇌의 전반적인 위축, 뇌실의 확장, 신경섬유의 다발성 병터(신경섬유뒤틀림)와 노인반(neuritic plaque) 등이 특징이다. 임상적인 특징은 점진적인 기억-판단-언어능력 등 지적인 기능의 감퇴와 일상생활능력-인격-행동양상의 장애이다. 병에 걸리면 초기에는 이름-날짜-장소와 같은 것들이 기억에서 사라지고, 심해지면 화장실을 가거나 요리를 하거나 신을 신는 일 등의 일상생활조차도 잊게 된다. 동시에 우울증세나 인격의 황폐, 격한 행동 등의 정신의학적인 증세도 동반된다. 이러한 증세들이 점전적으로 진행되어 결국은 죽음에 이르게 된다. 발병 후 서서히 죽음에 이르는 기간은 6~8년 정도이지만 사람에 따라 20년이 넘는 경우도 있다. |
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| AD | accident dispensary; acetate dialysis; active disease; acute dermatomyositis; addict, addiction; ade... |
|---|---|
| NFD | neurofibrillary degeneration |
| NFT | neurofibrillary tangle |
| CRD | carbohydrate-recognition domain; chronic renal disease; chronic respiratory disease; child restraint... |
| RD | radial deviation; radiology department; rate difference; Raynaud disease; reaction of degeneration; ... |
| NFD | Neurofibrillary degeneration |
|---|---|
| NFT | Neurofibrillary Tangles |
| ARMD | AGE-RELATED MACULAR DEGENERATION |
| AMD | Age related macular degeneration |
| CBD | Cortico-basal degeneration |
| neurofibrillary degeneration | Formation of coarse, argentophilic, intracytoplasmic fibres, often in complex tangles within intracranial nerve cells that are undergoing aging. See: Alzheimer's disease. (05 Mar 2000) |
|---|---|
| neurofibrillary tangle | <cell biology> Accumulation of twisted protein fragments inside nerve cells. Neurofibrillary tangles are one of the characteristic structural abnormalities found in the brains of patients with Alzheimer's disease patients. Upon autopsy, the presence of neuritic plaquesand neurofibrillary tangles is used to positively diagnose Alzheimer's disease. (22 May 1997) |
| neurofibrillary tangles | Abnormal structures located in various parts of the brain and composed of dense arrays of paired helical filaments (neurofilaments and microtubules). These double helical stacks of transverse subunits are twisted into left-handed ribbon-like filaments that likely incorporate the following proteins: 1) the intermediate filaments: medium- and high-molecular-weight neurofilaments; 2) the microtubule-associated proteins map-2 and tau; 3) actin; and 4) ubiquitin. As one of the hallmarks of alzheimer disease, the neurofibrillary tangles eventually occupy the whole of the cytoplasm in certain classes of cell in the neocortex, hippocampus, brainstem, and diencephalon. The number of these tangles, as seen in post mortem histology, correlates with the degree of dementia during life. Some studies suggest that tangle antigens leak into the systemic circulation both in the course of normal aging and in cases of alzheimer disease. (12 Dec 1998) |
| Alzheimer, Alois | <person> In 1901 a 51 year old woman, Auguste D, was admitted to the state asylum in Frankfurt. She was suffering from cognitive and language deficits, auditory hallucinations, delusions, paranoia and aggressive behaviour. She was studied by Alzheimer who was working at the hospital in Frankfurt. He moved to the medical school in Munich in 1903, to work with Emil Kraepelin, one of the formost German psychiatrists of that era. When Auguste D died in April 1906, her brain was sent to him for examination. In November 1906, Alzheimer presented her case at a psychiatry meeting and published his talk in 1907. In 1910, Kraepelin coined the term Alzheimer's disease - a term still in use today. Lived: 1864-1915. (05 Dec 1998) |
| alzheimer disease | A degenerative organic mental disease characterised by progressive brain deterioration and dementia. The disease was originally described as dementia, presenile occurring in persons under the age of 65 (as opposed to dementia, senile with onset at or after 65); however, onset may occur at any age. There is no pathophysiological nor clinical distinction between the two stages of onset of alzheimer's. Women appear to be affected twice as frequently as men. It is characterised pathologically by the triad of senile plaques, neurofibrillary tangles, and neuropil threads. (12 Dec 1998) |
| Alzheimer's dementia | <disease> A progressive, neurodegenerative disease characterised by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. The cause of nerve cell death is unknown but the cells are recognised by the appearance of unusual helical protein filaments in the nerve cells (neurofibrillary tangles) and by degeneration in cortical regions of brain, especially frontal and temporal lobes. Alzheimer's disease is the most common cause of dementia. (22 May 1997) |
| Alzheimer's disease | <disease> A progressive, neurodegenerative disease characterised by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. The cause of nerve cell death is unknown but the cells are recognised by the appearance of unusual helical protein filaments in the nerve cells (neurofibrillary tangles) and by degeneration in cortical regions of brain, especially frontal and temporal lobes. Alzheimer's disease is the most common cause of dementia. (22 May 1997) |
| Alzheimer's sclerosis | Hyaline degeneration of the medium and smaller blood vessels of the brain. (05 Mar 2000) |
| Alzheimer type I astrocyte | Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy. (05 Mar 2000) |
| Alzheimer type II astrocyte | Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease. (05 Mar 2000) |
| disease, alzheimer's | A progressive degenerative disease of the brain that leads to dementia. On a cellular level, Alzheimer's is characterised by unusual helical protein filaments in nerve cells (neurons) of the brain. These odd twisted filaments are called neurofibrillary tangles. On a functional level, there is degeneration of the cortical regions, especially the frontal and temporal lobes, of the brain. The U.S. President Ronald Reagan is said to have Alzheimer's disease. Named after the German neurologist Alois Alzheimer (1864-1915). (12 Dec 1998) |
| adipose degeneration | Abnormal formation of microscopically visible droplets of fat in the cytoplasm of cells, as a result of injury. Synonym: adipose degeneration, steatosis. (05 Mar 2000) |
| adiposogenital degeneration | A disorder characterised primarily by obesity and hypogonadotrophic hypogonadism in adolescent boys; dwarfism is rare, and when present is thought to reflect hypothyroidism. Visual loss, behavioural abnormalities, and diabetes insipidus may occur. Frohlich's syndrome often is used synonymously for this disorder, although the original case involved a pituitary tumour; most cases are thought to result from hypothalamic dysfunction in areas regulating appetite and gonadal development. The most common causes are pituitary and hypothalamic neoplasms. Synonym: adiposis orchica, adiposogenital degeneration, adiposogenital dystrophy, adiposogenital syndrome, hypophysial syndrome, hypothalamic obesity with hypogonadism. Origin: L. Fr. G. Dys-, bad, + trophe, nourishment (05 Mar 2000) |
| age-related macular degeneration | A common macular degeneration beginning with drusen of the macula and pigment disruption and sometimes leading to severe loss of central vision. (05 Mar 2000) |
| albuminous degeneration | An obsolete terms for cloudy swelling. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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