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4-14C Conversion of
4-AAF 4-acetylaminofluorene
4-ABP 4-Aminobiphenyl
4-AP 4 Aminopyridine
4-APP 4-Aminopyrazolopyrimidine
4-APP 4-amino-pyrazolo-(3,4 d) pyrimidine
4-CmC 4-Chloro-m-Cresol
4-CP 4-Chlorophenol
4-CPG S)-4-carboxy-phenylglycine
4-D Four-dimensional
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    4-Aminophenol derivatives
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    4-Aminophenol derivatives
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4-(4'-hydroxy-3'-methylbut-2'-enyl)-L-tryptophan synthetase <enzyme> Enzymatic synthesis of above cpd from isopentenylpyrophosphate and tryptophan
Registry number: EC 6.-
(26 Jun 1999)
4-alpha-d-glucanotransferase Dextrin transglycosylase or glycosyltransferase;a 4-glycosyltransferase converting maltodextrins into amylose and glucose by transferring parts of 1,4-glucan chains to new 4-positions on glucose or other 1,4-glucans.
Synonym: amylomaltase, D enzyme, dextrin glycosyltransferase, dextrin transglycosylase, disproportionating enzyme.
(05 Mar 2000)
4-aminobenzoate hydroxylase <enzyme> Catalyses decarboxylative hydroxylation of 4-aminobenzoate forming 4-hydroxyaniline in presence of NADPH and o2; fad-dependent monooxygenase from agaricus bisporus
Registry number: EC 1.14.13.27
(26 Jun 1999)
4-aminobenzoic acid <chemical> 4-aminobenzoic acid. A member of the vitamin b complex. It is also employed as a sunscreening agent. The potassium salt is used therapeutically in fibrotic skin disorders.
Pharmacological action: sunscreening agents.
Chemical name: Benzoic acid, 4-amino-
(12 Dec 1998)
4-aminobutyrate pathway The pathway that ultimately converts 4-aminobutyrate to succinate; succinate is then converted to alpha-ketoglutarate, via the tricarboxylic acid cycle, which is then acted upon by glutamate dehydrogenase; glutamate is then decarboxylated to reform 4-aminobutyrate; an important pathway for those cells which make this neuroactive molecule.
Synonym: GABA pathway.
(05 Mar 2000)
4-aminobutyrate transaminase <enzyme> An enzyme that converts brain gamma-aminobutyric acid (gaba) into succinate saemialdehyde, which can be converted to succinic acid and enter the citric acid cycle. It also acts on beta-alanine.
Chemical name: 4-Aminobutanoate:2-oxoglutarate aminotransferase
Registry number: EC 2.6.1.19
(12 Dec 1998)
4-aminopyridine <chemical> A potassium channel blocker. It is used primarily as a research tool and is helpful in characterizing subtypes of potassium channels. It has been used clinically in lambert-eaton syndrome and multiple sclerosis because by blocking potassium channels it prolongs action potentials thereby increasing transmitter release at the neuromuscular junction (and elsewhere).
Chemical name: 4-Pyridinamine
(12 Dec 1998)
4-androstene-3,17-dione-16 beta-hydroxylase <enzyme> Catalyses androst-4-en-3,17-dione to 16 beta-hydroxyandrost-4-en-3,17-dione; cytochrome p450 2b1 is both a androstenedione 16beta-hydroxylase and a testosterone 16beta-hydroxylase
Registry number: EC 1.14.99.-
Synonym: aedo-16-hydroxylase, steroid 16-hydroxylase, cytochrome p450 2b2, cyp 2b2, cyp2b2
(26 Jun 1999)
4-butyrolactone <chemical> Dihydro-2(3h)-furanone. An endogenous compound, made from gamma-aminobutyrate and the precursor of gamma-hydroxybutyrate, it is also used as a pharmacological agent. It apparently acts as a modulator at the picrotoxin binding site of gaba-a receptors, and may also affect gaba-b receptors. It is used mainly as an experimental tool. Among other systemic effects, it causes increase of brain dopamine by inhibiting its release from nerve terminals. It is also used as an industrial solvent and precursor.
Pharmacological action: gaba modulators, solvents.
Chemical name: 2(3H)-Furanone, dihydro-
(12 Dec 1998)
4-carboxyglutamic acid A carboxylated form of glutamic acid found in certain proteins (e.g., prothrombin, factors VII, IX, and X, osteocalcin). Its synthesis is vitamin K-dependent.
(05 Mar 2000)
4-carboxymethyl-methylbut-2-ene-1,4-olide isomerase <enzyme> From alcaligenes eutrophus; catalyses the formation of 3-methyl-2-ene-lactone from 4-methyl-2-ene-lactone
Registry number: EC 5.4.99.-
Synonym: 4-methyl-2-enelactone isomerase
(26 Jun 1999)
4-chlorobenzoate dehalogenase <enzyme> Dehalogenates 4-chlorobenzoate to yield 4-hydroxybenzoate
Registry number: EC 3.8.1.6
Synonym: 4-chlorobenzoate-4-hydroxylase
(26 Jun 1999)
4-chlorobenzoyl coenzyme A dehalogenase <enzyme> Converts 4-chlorobenzoyl-CoA to 4-hydroxybenzoyl-CoA; not active on 4-chlorobenzoic acid
Registry number: EC 3.8.1.-
Synonym: 4-cba-CoA dehalogenase, 4-chlorobenzoate-CoA dehalogenase
(26 Jun 1999)
4-chloromercuribenzenesulfonate <chemical> Hydrogen chloro(4-sulfonatophenyl)mercurate(1-). A cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology.
Pharmacological action: sulfhydryl reagents, enzyme inhibitors.
Chemical name: Mercurate(1-), chloro(4-sulfonatophenyl)-, hydrogen
(12 Dec 1998)
4-chlorophenylacetate 3,4-dioxygenase <enzyme> Forms 3,4-dihydroxyphenylacetate; probable mechanism involves a dioxygenated intermediate from which cl is released
Registry number: EC 1.13.11.-
Synonym: 4-cpa 3,4-dioxygenase
(26 Jun 1999)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone - »õâ Inhibitor of phosphodiesterases.
    Synonyms : Ro 1724, Ro 20 1724, Ro 20-1724, Ro 201724
  • 4-1BB Ligand - »õâ A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.
    Synonyms : 4-1BBL Protein, CD137 Ligand, Tumor Necrosis Factor (Ligand) Superfamily, Member 9, 4 1BB Ligand, 4 1BBL Protein
  • 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid - »õâ A non-penetrating amino reagent (commonly called SITS) which acts as an inhibitor of anion transport in erythrocytes and other cells.
    Synonyms : 4-Acetamido-4'-isothiocyanatostilbene-2, 2'-disulfonic Acid, Disodium Salt, SITS, SITS Disodium Salt, 4 Acetamido 4' isothiocyanatostilbene 2, 2' disulfonic Acid, Disodium Salt, SITS
  • 4-Aminobenzoic Acid - »õâ A member of the VITAMIN B COMPLEX. It used to be common in SUNSCREENING AGENTS until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
    Synonyms : Aminobenzoic Acid, Magnesium para-Aminobenzoate, Paraminol, Potaba, 4 Aminobenzoic Acid, p Aminobenzoic Acid, para Aminobenzoic Acid, para-Aminobenzoate, Magnesium
  • 4-Aminobutyrate Transaminase - »õâ An enzyme that converts brain gamma-aminobutyric acid (GAMMA-AMINOBUTYRIC ACID) into succinate semialdehyde, which can be converted to succinic acid and enter the citric acid cycle. It also acts on beta-alanine. EC 2.6.1.19.
    Synonyms : GABA Aminotransferase, GABA-alpha-Ketoglutarate Aminotransferase, 4 Aminobutyrate Transaminase, Aminotransferase, Aminobutyrate, Aminotransferase, GABA, Aminotransferase, GABA-alpha-Ketoglutarate, Aminotransferase, beta-Alanine Ketoglutarate
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4-a.’s a group of antimalarial compounds effective against the erythrocytic forms of Plasmodium and including amodiaquine, chloroquine, and hydroxychloroquine.
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4-h. γ-h. a.
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4-hydroxy-2-oxoglutarate aldolase [EC 4.1.3.16] an enzyme of the lyase class that catalyzes the cleavage of 4-hydroxy-α-ketoglutarate to form pyruvate and glyoxylate. The reaction is a step in the degradation of free hydroxyproline.
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4-hydroxybutyricaciduria succinic semialdehyde dehydrogenase deficiency.
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