| 영문 | iron deficiency anemia | 한글 | 철결핍빈혈 |
|---|---|---|---|
| 설명 | 적혈구의 기능은 산소를 운반하는데 있다. 적혈구 속에 산소와 결합을 하여 산소를 운반하는 혈색소라는 물질이 있다. 철은 이 혈색소의 중요한 부분을 이루는 것으로 철이 없으면 혈색소가 만들어질 수가 없다. 혈색소가 없으면 역시 적혈구도 만들어지지 않으므로 체내에 철이 부족하면 빈혈이 생긴다. 이 철결핍성 빈혈은 빈혈의 원인 중에서 가장 흔한 것이다(약 25%를 차지한다). 철저장량의 저하-결핍, 혈청철농도의 저하, 트란스페린량 상승, 트란스페린포화도의 저하, 혈색소농도 또는 헤마토크리트의 저하, 저색소성대적혈구를 특징으로 하는 빈혈로서, 생체 내에서 철이 장기에 걸쳐 결핍되며 그 때문에 혈색소 생산 감소에 의해 일어난다. 창자에서의 철흡수량 부족, 철의 수요 증대(유아기, 사춘기, 임신), 철소실과잉(출혈)에 의해 일어나며, 특히 사춘기에서 폐경기까지의 여성에게 많다. 증상으로서는 얼굴창백, 피로감, 피부창백, 손톱 변화(스푼 모양) 등을 나타낸다. 구강 영역에서는 혀의 접촉통, 발적, 건조감, 삼킴곤란을 수반하면 플러머-빈슨(Plummer-Vinson)증후군이라고 한다. 혈액 소견은 혈청철은 저하하며, 철결합능력의 상승, 저색소성 작은적혈구성을 나타낸다. |
||
| MCD | magnetic circular dichroism; mast-cell degranulation; mean cell diameter; mean of consecutive differ... |
|---|---|
| MD | Doctor of Medicine [Lat. Medicinae Doctor]; magnesium deficiency; main duct; maintenance dose; major... |
| MADD | Mothers Against Drunk Driving; multiple acyl-CoA dehydrogenase deficiency |
| IGD | idiopathic growth hormone deficiency; interglobal distance; isolated gonadotropin deficiency |
| DDC | L-Dopa De-Carboxylase |
| ACC | Acetyl-CoA carboxylase |
|---|---|
| ACCase | Acetyl-CoA carboxylase |
| PCC | Propionyl CoA carboxylase |
| HMG CoA | 3-hydroxy-3-methylglutaroyl CoA |
| HMG-CoA reductase | 3-Hydroxy-3-methylglutaryl CoA reductase |
| multiple carboxylase deficiency | Abnormalities in carbohydrate and branched-chain amino acid catabolism that are responsive to biotin therapy. It may be due to deficiency of propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, biotinidase, or propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, and pyruvate carboxylase. (12 Dec 1998) |
|---|---|
| pyruvate carboxylase deficiency | An autosomal recessive pyruvate metabolism disorder resulting from absent or deficient expression of pyruvate carboxylase activity. Decreased production of oxaloacetate leads to decreased gluconeogenesis, thereby causing fasting hypoglycaemia, lactic acid acidosis, and decreased synthesis of amino acid neurotransmitters. Clinical presentations include acidosis, ataxia, mental retardation; sometimes co-occurs with leigh disease. (12 Dec 1998) |
| acetyl-CoA carboxylase | <enzyme> A carboxylating enzyme that catalyses the conversion of ATP, acetyl-CoA, and hco3- to ADP, orthophosphate, and malonyl-CoA. It is a biotinyl-protein that also catalyses transcarboxylation. The plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA Chemical name: Acetyl-CoA:carbon-dioxide ligase (ADP-forming) Registry number: EC 6.4.1.2 (12 Dec 1998) |
| acetyl CoA carboxylase phosphatase | <enzyme> Phosphatase occurs in complex with the carboxylase Registry number: EC 3.1.3.- Synonym: acc-phosphatase, acetyl coenzyme a carboxylase phosphatase (26 Jun 1999) |
| acyl-CoA carboxylase | <enzyme> Catalyses carboxylation (ATP, mg ++, mco(3)-dependent) of acetyl-CoA, propionyl CoA, and butyryl CoA; from nematode turbatrix aceti Registry number: EC 6.4.1.- Synonym: acyl-coenzyme a carboxylase (26 Jun 1999) |
| propionyl-CoA carboxylase | <enzyme> See also propionyl CoA carboxylase (ATP-hydrolyzing) (EC 6.4.1.4) Registry number: EC 4.1.1.41 Synonym: methylmalonyl-CoA decarboxylase, propionyl-coenzyme a carboxylase (26 Jun 1999) |
| butyryl-CoA acetoacetate CoA transferase | <enzyme> Butyryl-CoA + acetoacetate yields butyrate + acetoacetyl-CoA Registry number: EC 2.8.3.- Synonym: butyryl-coenzyme a acetoacetate coenzyme a transferase (26 Jun 1999) |
| malonyl-CoA-acetyl CoA-acyl carrier protein S-acyltransferase | <enzyme> Specific for either malonyl-CoA or acetyl-CoA; a component of fatty acid synthase Registry number: EC 2.8.3.- Synonym: mcoa-acoa acp acyltransferase (26 Jun 1999) |
| succinyl-CoA-3-hydroxy-3-methylglutarate CoA transferase | <enzyme> Rat liver mitochondrial enzyme which catalyses transfer of a conezyme a molecule from succinyl-CoA to 3-hydroxy-3-methylglutarate Registry number: EC 2.8.3.- Synonym: succinylcoa-hmg CoA transferase, sca-hmg cat (26 Jun 1999) |
| succinyl CoA propionate CoA-transferase | <enzyme> Succinyl CoA and propionate gives propionyl CoA and succinate Registry number: EC 2.8.3.- Synonym: succinyl coenzyme a propionate coenzyme a-transferase (26 Jun 1999) |
| enoyl-CoA hydratase - 3-hydroxyacyl-CoA dehydrogenase - dodecanoyl-coenzyme A delta-isomerase | <chemical> Catalyses the second and third reactions of the fatty acid beta-oxidation cycle, converting enoyl-CoA to 3-ketoacyl-CoA; EC 4.2.1.17 and EC 1.1.1.35 and EC 5.3.3.8; consider also multifunctional protein-a Synonym: peroxisomal bifunctional enzyme, enoyl-coenzyme a hydratase -- 3-hydroxyacyl-coenzyme a dehydrogenase, peroxisomal trifunctional enzyme, delta(3), delta(2)-enoyl-CoA isomerase--2-enoyl-CoA hydratase--3-hydroxyacyl-CoA dehydrogenase (26 Jun 1999) |
| acetone carboxylase | <enzyme> An ATP-dependent carboxylase Registry number: EC 4.1.1.- (26 Jun 1999) |
| biotin carboxylase | <enzyme> A subunit of acetyl-CoA carboxylase Registry number: EC 6.3.4.14 (26 Jun 1999) |
| carboxylase | 1. One of several carboxy-lyases, trivially named carboxylases or decarboxylases (EC subclass 4.1.1), catalyzing the addition of CO2 to all or part of another molecule to create an additional -COOH group (e.g., ribulose-1,5-bisphosphate carboxylase). 2. Obsolete name for pyruvate decarboxylase. (05 Mar 2000) |
| gamma-glutamyl carboxylase | <enzyme> An enzyme that catalyses the formation of gamma-carboxyglutamyl residues in many proteins, several appearing in the blood clotting cascade. (05 Mar 2000) |
| 3-methylcrotonyl CoA carboxylase deficiency |
an autosomal recessive aminoacidopathy due to deficiency of methylcrotonoyl-CoA carboxylase, characterized by increased urine levels of 3-methylcrotonylglycine, 3-methylcrotonic acid, and 3-hydroxyisovaleric acid and variable presentation of mental retardation, central nervous system dysfunction, and muscular atrophy. Written also β-methylcrotonyl CoA carboxylase deficiency.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|