| 3-methylcholanthrene | A highly carcinogenic hydrocarbon that can be formed chemically from deoxycholic or cholic acids, or from cholesterol; the choice between 3-or 20-for the methyl group depends upon whether hydrocarbon (inner) or steroid (outer) numbering is chosen; in the latter case, the formal relationship to the cholic acids and cholesterol is clear. (05 Mar 2000) |
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| 3-methylcholanthrene |
a highly carcinogenic polycyclic aromatic hydrocarbon synthesized by pyrolytic degradation of cholic acid, deoxycholic acid, or cholesterol. It is a procarcinogen that requires metabolic activation to exert a mutagenic effect and is widely used in laboratory studies of chemical carcinogenesis. Abbreviated MCA.
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