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3-M [syndrome] initials for Miller, McKusick, and Malvaux, who first described the syndrome
3-MT 3-methoxytyramine
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3-MC 3- methylcholanthrene
3-MCA 3-methylcholanthrene
3-meAde 3-methyl-adenine
3-MeO-AAB 3-Methoxy-4-aminoazobenzene
3-MG 2-O-methyl-D-glucose
3-MP 3-Mercaptopropionic acid
3-MPA 3-mercapto-propionic acid
3-MX 3-Methylxanthine
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 13 ÆäÀÌÁö: 1
3-mercaptolactate A product of cysteine catabolism; formed by the action of lactate dehydrogenase on 3-mercaptopyruvate that was, in turn, formed by transamination of cysteine; present in normal human urine as a mixed disulfide with cysteine; elevated in the urine in individuals with mercaptolactate-cysteine disulfiduria.
(05 Mar 2000)
3-mercaptopropionic acid <chemical> 3-mercaptopropionic acid. An inhibitor of glutamate decarboxylase. It decreases the gaba concentration in the brain, thereby causing convulsions.
Pharmacological action: convulsants, gaba agents, enzyme inhibitors.
Chemical name: Propanoic acid, 3-mercapto-
(12 Dec 1998)
3-mercaptopyruvate The transaminated product of cysteine; formed in cysteine catabolism; elevated in individuals with a deficiency of 3-mercaptopyruvate sulfurtransferase.
3-mercaptopyruvate sulfurtransferase, an enzyme that is a part of the cysteine catabolic pathway; it catalyses the conversion of 3-mercaptopyruvate to pyruvate and H2S; a deficiency of this enzyme will result in elevated urine concentrations of 3-mercaptopyruvate as well as of 3-mercaptolactate, both in the form of disulfides with cysteine.
(05 Mar 2000)
3-methoxy-4-hydroxymandelic acid Misnomer for 4-hydroxy-3-methoxymandelic acid (a,3-dihydroxy-2-methoxybenzeneacetic acid);the major urinary metabolite of adrenal and sympathetic catecholamines (e.g., from both epinephrine and norepinephrine); elevated in most patients with pheochromocytoma.
Acronym: VMA
(05 Mar 2000)
3-methoxy-4-hydroxymandelic acid test A test for catecholamine-secreting tumours (pheochromocytoma and neuroblastoma) performed on a 24-hr urine specimen; it is based on the fact that vanillylmandelic acid is the major urinary metabolite of norepinephrine and epinephrine.
Synonym: 3-methoxy-4-hydroxymandelic acid test, VMA test.
(05 Mar 2000)
3-methoxy-4-hydroxyphenylethanol <chemical> 3-methoxy-4-hydroxyphenylethanol. Metabolite of serotonin and norepinephrine.
Chemical name: Benzeneethanol, 4-hydroxy-3-methoxy-
(12 Dec 1998)
3-methyl-2-oxobutanoate hydroxymethyltransferase <enzyme> Methylenetetrahydrofolate and alpha-ketoisovalerate gives tetrahydrofolate and ketopantoate
Chemical name: 5,10-methylenetetrahydrofolate alpha-ketoisovalerate hydroxymethyltransferase
Registry number: EC 2.1.2.11
Synonym: iphm transferase, panb protein, ketopantoate hydroxymethyltransferase
(26 Jun 1999)
3-methylbenzylalcohol dehydrogenase <enzyme> Involved in m-xylene metabolism by pseudomomas paucimobilis
Registry number: EC 1.1.1.-
(26 Jun 1999)
3-methylcholanthrene A highly carcinogenic hydrocarbon that can be formed chemically from deoxycholic or cholic acids, or from cholesterol; the choice between 3-or 20-for the methyl group depends upon whether hydrocarbon (inner) or steroid (outer) numbering is chosen; in the latter case, the formal relationship to the cholic acids and cholesterol is clear.
(05 Mar 2000)
3-methylcrotonyl-CoA (CH3)2C==CHCOSCoA;an intermediate in the degradation of l-leucine; accumulates in a deficiency of 3-methylcrotonyl-CoA carboxylase.
3-methylcrotonyl-CoA carboxylase, an enzyme in the pathway of l-leucine degradation that catalyses the reaction of 3-methylcrotonyl-CoA with CO2, ATP, and water to form ADP, orthophosphate, and 3-methylglutaconyl-CoA; a deficiency of this enzyme causes episodes of severe metabolic acidosis.
(05 Mar 2000)
3-methylglutaconic aciduria Elevated levels of 3-methylglutaconic acid in the urine. An inherited disorder whose mild form is a result of a deficiency of 3-methylglutaconyl-CoA hydratase, leading to delayed speech development.
(05 Mar 2000)
3-methylglutaconyl-CoA hydratase <enzyme> An enzyme that catalyses the reaction of trans-3-methylglutaconyl-CoA and water to form 3-hydroxy-3-methylglutaconyl-CoA; this enzyme participates in the pathway for l-leucine degradation; a deficiency of this enzyme will result in 3-methylglutaconic aciduria.
(05 Mar 2000)
3-methylitaconate delta-isomerase <enzyme> Catalyses reversibly the isomerization of methylitaconate to dimethylmaleate
Registry number: EC 5.3.3.6
Synonym: 3-midiase
(26 Jun 1999)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 1
  • 3-Mercaptopropionic Acid - »õâ An inhibitor of glutamate decarboxylase. It decreases the GAMMA-AMINOBUTYRIC ACID concentration in the brain, thereby causing convulsions.
    Synonyms : 3 Mercaptopropanoic Acid, 3 Mercaptopropionic Acid, Acid, 3-Mercaptopropanoic, Acid, 3-Mercaptopropionic, beta Mercaptopropionate
  • 3-Methoxy-4-hydroxyphenylethanol - »õâ Metabolite of serotonin and norepinephrine.
    Synonyms : 3 Methoxy 4 hydroxyphenylethanol, Alcohol, Hydroxymethoxyphenethyl
  • 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) - »õâ A ketone oxidoreductase that catalyzes the overall conversion of alpha-keto acids to ACYL-CoA and CO2. The enzyme requires THIAMINE DIPHOSPHATE as a cofactor. Defects in genes that code for subunits of the enzyme are a cause of MAPLE SYRUP URINE DISEASE. The enzyme was formerly classified as EC 1.2.4.3.
    Synonyms : 2-Oxoisocaproate Dehydrogenase, Alpha-Keto Acid Dehydrogenase, BCKA Decarboxylase, Branched Chain Alpha-Keto Acid Decarboxylase, Branched Chain Ketoacid Dehydrogenase, Branched-Chain 2-Oxo Acid Dehydrogenase, Branched-Chain Keto Acid Dehydrogenase
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3-methyl-2-oxobutanoate dehydrogenase (lipoamide) [EC 1.2.4.4] an enzyme of the oxidoreductase class that is a component of the multienzyme branched-chain α-keto acid dehydrogenase complex (q.v.). The enzyme catalyzes the oxidative decarboxylation of the branched chain amino acids leucine, isoleucine, and valine, transferring the products formed to the lipoic acid moiety of dihydrolipoamide acyltransferase via a thiamine pyrophosphate cofactor. See also maple syrup urine disease, under disease. Called also α-ketoisovalerate dehydrogenase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
3-methylcholanthrene a highly carcinogenic polycyclic aromatic hydrocarbon synthesized by pyrolytic degradation of cholic acid, deoxycholic acid, or cholesterol. It is a procarcinogen that requires metabolic activation to exert a mutagenic effect and is widely used in laboratory studies of chemical carcinogenesis. Abbreviated MCA.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
3-methylcrotonic acid crotonic acid methylated at the 3 carbon; it is excreted at elevated levels in urine when 3-methylcrotonoyl-CoA carboxylase activity is impaired.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
3-methylcrotonyl the radical of 3-methylcrotonic acid; the thioester formed with coenzyme A, 3-methylcrotonyl CoA, is an intermediate in the degradation of leucine.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
3-methylcrotonyl CoA carboxylase deficiency an autosomal recessive aminoacidopathy due to deficiency of methylcrotonoyl-CoA carboxylase, characterized by increased urine levels of 3-methylcrotonylglycine, 3-methylcrotonic acid, and 3-hydroxyisovaleric acid and variable presentation of mental retardation, central nervous system dysfunction, and muscular atrophy. Written also β-methylcrotonyl CoA carboxylase deficiency.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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