| ¿µ¹® | steroid | ÇÑ±Û | ½ºÅ×·ÎÀ̵å |
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| ¼³¸í | Hydrogenated cyclopentanoperhydrophenanthrene ring systemÀ¸·Î ±¸¼ºµÈ ºÐÀÚ. »ýü³»¿¡¼ Áß¿äÇÑ ½ºÅ×·ÎÀ̵å´Â ºÎ½Å°ÑÁú¿¡¼ »ý¼ºµÇ´Â ½ºÅ×·ÎÀ̵å È£¸£¸óÀÌ¸ç ´ç´ë»ç¿¡ °ü¿©ÇÏ´Â ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å(glucocorticoid), ¿°·ù´ë»ç(ÀÎü³» Á¸ÀçÇÏ´Â ¿°ºÐ¼ººÐ(NaCl, KCl, NaOH µî)À» Á¶ÀýÇÏ´Â ´ë»ç)¿¡ °ü¿©ÇÏ´Â ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å(mineralocorticoid), ¼ºÈ£¸£¸ó(ÀÎüÀÇ ¼º¹ß´Þ¿¡ °ü¿©)ÀÇ ¼¼ °¡ÁöÀÌ´Ù. ½ºÅ×·ÎÀ̵å È£¸£¸óÀº ºÎ½ÅÇÇÁú¿¡¼ ÄÝ·¹½ºÅ×·ÑÀ» Àç·á·Î ÇÏ¿© º¹ÀâÇÑ ÇÕ¼º´Ü°è¸¦ °ÅÃÄ ÇÕ¼ºµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â ³úÇϼöü¿¡¼ ºÐºñµÇ´Â ºÎ½Å°ÑÁúÀÚ±Ø È£¸£¸ó(ACTH)¿¡ ÀÇÇØ »ý¼º°ú ºÐºñ°¡ ÀÌ·ç¾îÁö³ª ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å´Â ·¹´Ñ-¾ÈÁö¿ÀÅٽŰè(½ÅÀå¿¡¼ ÀÎü³» ¿°ºÐÀÌ ºÎÁ·½Ã ·¹´ÑÀÌ ºÐºñµÇ°í, ÀÌ ÀÚ±ØÀº ºÎ½ÅÀ¸·Î ÀüÇØÁ® ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵åÀÎ ¾ÈÁö¿ÀÅÙ½ÅÀ» ºÐºñÇÏ°Ô µÊ)ÀÇ Àڱؿ¡ ÀÇÇØ ºÐºñµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â transcortin°ú °áÇÕÇÏ¿© ¿î¹ÝµÇ¸ç ¹Ý°¨±â´Â Çѽð£ Á¤µµÀ̳ª ¿°·ùÄÚ¸£Æ¼ÄÚÀ̵å´Â ´ëºÎºÐÀÌ ´Ü¹éÁú°ú °áÇÕÇÏÁö ¾Ê°í À¯¸®ÇüÀ¸·Î ³²¾ÆÀÖ¾î ¹Ý°¨±â´Â 20ºÐ¿¡ ºÒ°úÇÏ´Ù. À̵éÀÌ °£¿¡ µµ´ÞÇϸé glucuronic acid¿¡ °áÇÕÇÏ¿© ¹è¼³µÈ´Ù. |
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| ¿µ¹® | enzyme-linked immunoabsorbent assay | ÇÑ±Û | È¿¼Ò¸é¿ªÃøÁ¤¹ý |
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| ¼³¸í | È¿¼Ò°áÇո鿪ÈíÂøÁ¦ °ËÁ¤¹ýÀ¸·Î ¹ø¿ªµÇ°í ÀÖ´Ù. ÀÌ ¹ýÀº Ç׿ø(¶Ç´Â Ç×ü)¿¡ ¾ËÄ®¸® Æ÷½ºÆÄŸ¾ÆÁ¦ ¶Ç´Â Æä¸£¿Á½Ãµð¾ÆÁ¦ µîÀÇ »ê¼Ò¸¦ °áÇÕ½ÃÄÑ µÎ°í ±× »ê¼ÒȰ¼ºÀ» ÁöÇ¥·Î »ï¾Æ Ç׿øÇ×ü¹ÝÀÀÀÇ Á¤µµ¸¦ ¾È ´ÙÀ½ ¿©±â¿¡¼ Ç׿ø(¶Ç´Â Ç×ü)ÀÇ ¾çÀ» ±¸ÇÏ´Â °ÍÀÌ´Ù. ÀÌ ¹ýÀÇ ÀÌÁ¡À¸·Î¼ °í°¨µµ, Á¶ÀÛÀÇ °£´ÜÇÔ ¹× ¹æ»ç¼±¸é¿ªÃøÁ¤¹ýó·³ ¹æ»ç¼º¹°ÁúÀ» »ç¿ëÇÏÁö ¾Ê¾Æµµ µÈ´Ù´Â Á¡À» µé ¼ö ÀÖ´Ù. È£¸£¸óÀ̳ª ¸é¿ª±Û·ÎºÒ¸°ÀÇ Á¤·®¹ýÀ¸·Î¼ ÀÀ¿ë µÇ°í ÀÖÀ¸¸ç ÃøÁ¤¿ë ŰƮµµ ½ÃÆÇµÇ°í ÀÌÀÖ´Ù. |
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| ¿µ¹® | test | ÇÑ±Û | °Ë»ç |
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| ¼³¸í | ¾î¶² ´Ù¸¥ ¹°ÁúÀ» °ËÃâ, ÃøÁ¤, »ý¼ºÇϱâ À§ÇÑ Æ¯Á¤ÇÑ ÈÇйÝÀÀÀ» ÀÏÀ¸Å°´Âµ¥ »ç¿ëµÇ´Â ¹æ¹ý. |
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| ¿µ¹® | scratch test | ÇÑ±Û | ³Àý¹ý |
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| ¼³¸í | ÇǺθ¦ ³¯Ä«·Î¿î ¹Ù´Ã·Î ±Ü¾î ÇǺÎÀÇ ¹ÝÀÀÀ» º¸´Â °Ë»ç·Î ÇǺΠ°ú¹Î¹ÝÀÀÀ̳ª ¾Ë·¹¸£±â¸¦ ¾Ë¾Æº¸±â À§ÇÑ °Ë»çÀÌ´Ù. ¹Ù´Ã³¡¿¡ Ç׿øÀ» ¹¯Èù µÚ, ÇǺιØÀ» ±Ü¾î ¹ÝÀÀÀ» ¾Ë¾Æº»´Ù. À̶§ Ç׿øÀÌ ¾Æ´Ñ ´ëÁ¶¹°Áú(¿¹¸¦ µé¾î º¸ÅëÀÇ ¹°)À» ¹¯Èù ¹Ù´ÃÀ» °°ÀÌ ¹ÝÀÀÇÏ¿© ÇǺ馱âÁõ(dermographism) ´ÜÁö ¹Ù´ÃÀÇ ±ÜÈû¸¸À¸·Î ¾Ë·¹¸£±â °°Àº ¹ÝÀÀÀ» ÀÏÀ¸Å°´Â Çö»ó°ú °¨º°ÇØ¾ß ÇÑ´Ù. ³Ã», û·Â¼Ò½Ç(hearing loss) û°¢ÀÌ ÀúÇÏ ¶Ç´Â »ó½ÇµÈ »óÅÂ. ¿øÀΰú Á¤µµ´Â ¿©·¯ °¡ÁöÀε¥, ³Ã»Àº ±× Á¤µµ°¡ °¡Àå ½ÉÇÑ »óÅÂÀÌ´Ù. û°¢ÀÇ Àüµµ°æ·Î¿¡ Àå¾Ö°¡ ÀÖÀ» ¶§ ³Ã»ÀÌ ÀϾ°í, ±× º´ÅͰ¡ ¿ÜÀ̵µ³ª ÁßÀÌ¿¡ ÀÖ´Â °ÍÀ» ÀüÀ½³Ã», ³»ÀÌ¿¡ ÀÖ´Â °ÍÀ» °¨À½ ³Ã»À̶ó ÇÏ¿© ±¸ºÐÇÑ´Ù. ¶Ç º´ÅÍÀÇ ÀÚ¸®¸¦ ¸í½ÃÇÏ¿© ÁßÀ̼º ³Ã»À̳ª ¹Ì·Î¼º ³Ã» µîÀ¸·Î ¼¼ºÐÇϱ⵵ ÇÑ´Ù. |
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| ¿µ¹® | stool guaiac test | ÇÑ±Û | ´ëº¯ ±¸¾ÆÀÌ¾Ç °Ë»ç |
|---|---|---|---|
| ¼³¸í | ´ëº¯³»¿¡ ÀÖÀ» ¼ö ÀÖ´Â ÀáÇ÷(´«¿¡ º¸ÀÌÁö ¾Ê´Â ÃâÇ÷)À¯¹«¸¦ °Ë»çÇÏ´Â ¹æ¹ýÀ¸·Î, Ç÷±¸³»ÀÇ heme peroxidase¿¡ ÀÇÇØ guaiacÀÌ »êȵǴ ¹ÝÀÀÀ» ÀÌ¿ëÇÏ¿© ÃøÁ¤ÇÑ´Ù. ¹æ¹ýÀº 3Àϰ£¿¡ °ÉÃÄ ÇÑ º¯¿¡¼ 2±ºµ¥¾¿ äÃëÇÏ¿© °Ë»çÇÑ´Ù. À§¾ç¼º ¹ÝÀÀ(°ÅÁþÀ¸·Î Ç÷¾×ÀÌ ÀÖ´Ù°í ³ªÅ¸³ª´Â ¹ÝÀÀ)Àº ½Ä¹° °ú»êÈÈ¿¼Ò¸¦ ÇÔÀ¯Çϰí ÀÖ´Â È«´ç¹«ÀÇ ¼·Ã볪 Ç÷±¸ ¼ººÐÀ» ÇÔÀ¯Çϰí ÀÖ´Â °í±â ¼·Ãë µî¿¡¼ ³ªÅ¸³¯ ¼ö ÀÖÀ¸¸ç, À§À½¼º ¹ÝÀÀ(½ÇÁ¦·Î Ç÷¾×Àº ÀÖÁö¸¸, Ç÷¾×ÀÌ ¾ø´Ù°í ³ªÅ¸³ª´Â ¹ÝÀÀ)Àº ȯ¿ø·ÂÀ» °¡Áö°í ÀÖ´Â ºñŸ¹Î CÀÇ º¹¿ë½Ã ³ªÅ¸³¯ ¼ö ÀÖ´Ù. ƯÈ÷ À§¾ç¼º ¹ÝÀÀÀÌ ¸Å¿ì ÈçÇÏ´Ù. |
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| PAT | Pain Apperception Test; paroxysmal atrial tachycardia; patient; phenylaminotetrazole; physical abili... |
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| STS | sequence tagged site; serologic test for syphilis; sodium tetradecyl sulfate; sodium thiosulfate; st... |
| CAT | California Achievement Test; capillary agglutination test; catalase; cataract; catecholamine; Childr... |
| TAT | tetanus antitoxin; thematic apperception test; thematic aptitude test; thrombin-antithrombin complex... |
| LAI assay | Leukocyte Adherence Inhibition assay |
| 3 beta-HSD | 3 beta hydroxy steroid dehydrogenase |
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| 3 beta-HSD | 3 beta-hydroxy-steroid dehydrogenase/delta 5-delta 4 isomerase |
| AAS | Anabolic androgenic steroid |
| NSAID | Non Steroid Anti-Inflammatory Drugs |
| SBP | Steroid Binding Protein |
| 17-ketogenic steroid assay test | A colourimetric test, based on the Zimmermann reaction, which indicates metabolites or adrenal and testicular steroids excreted as 17-ketones in the urine; increased values are most striking in adrenocortical tumours, decreased values in Addison's disease or in panhypopituitarism. Synonym: ketogenic corticoids test. (05 Mar 2000) |
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| leukocyte adherence assay test | A test to detect the ability of leukocytes to adhere to bacteria, performed in vitro using nylon fibres to measure adherence. (05 Mar 2000) |
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| leukocyte bactericidal assay test | A test of leukocytes to determine their ability to kill a culture of live bacteria. (05 Mar 2000) |
| anabolic steroid | <endocrinology> A type of steroid hormone that stimulates the synthesis of protein. Anabolic steroids are compounds which stimulate the body into anabolism. This process involves the building of complex compounds from smaller simpler ones (for example proteins are built from amino acids). This process requires energy. (13 Nov 1997) |
| receptors, steroid | Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behaviour of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes. (12 Dec 1998) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| saturated steroid 6 alpha-hydroxylase | <enzyme> Acts on 5 alpha-androstane-3 beta,17 beta-diol and 5 alpha-pregnan-3 beta-ol-20-one; does not require cytochrome p-450 Registry number: EC 1.14.99.- Synonym: sat steroid 6alpha-hydroxylase (26 Jun 1999) |
| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| steroid | A group name for lipids that contain a hydrogenated cyclopentanoperhydrophenanthrene ring system. Some of the substances included in this group are progesterone, adrenocortical hormones, the gonadal hormones, cardiac aglycones, bile acids, sterols (such as cholesterol), toad poisons, saponins and some of the carcinogenic hydrocarbons. (18 Nov 1997) |
| steroid 11-alpha-hydroxylase | <enzyme> Converts 11-deoxycortisol to 11-alpha cortisol (the 11-alpha isomer of hydrocortisone) Registry number: EC 1.14.99.- (26 Jun 1999) |
| steroid 11 beta-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal tissues. It catalyses the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-haem iron protein, and cytochrome p-450. Its deficiency is a cause of congenital adrenal hyperplasia (adrenal hyperplasia, congenital). Chemical name: Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating) Registry number: EC 1.14.15.4 (12 Dec 1998) |
| steroid 12-monooxygenase | <enzyme> A steroid hydroxylase found in liver microsomes. It catalyses the 12-hydroxylation of steroids in the presence of NADPH, cytochrome p-450, and molecular oxygen. It is an important enzyme in the synthesis of cholic acid from cholesterol in the liver. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating) Registry number: EC 1.14.99.- (12 Dec 1998) |
| steroid 14-alpha-hydroxylase | <enzyme> From induced vegetative cell cultures of mucor piriformis; hydroxylates progesterone to 14-alpha-hydroxyprogesterone in the presence of NADPH and oxygen Registry number: EC 1.14.13.- Synonym: progesterone 14-alpha-hydroxylase (26 Jun 1999) |
| steroid 15-beta-hydroxylase | <enzyme> Contains p-450 and ferredoxin; from bacillus megaterium Registry number: EC 1.14.99.- Synonym: cytochrome p-450 15 beta-hydroxylase, p-450 (15-beta), steroid-15 beta-monooxygenase, cytochrome p-450meg, cytochrome p4502c12, cyp2c12 protein (26 Jun 1999) |
| steroid 17 alpha-monooxygenase | <enzyme> A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyses the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) Registry number: EC 1.14.99.9 (12 Dec 1998) |
| steroid 19-hydroxylase | <enzyme> Enzyme from adrenal mitochondria; forms 19-hydroxy-11-deoxycorticosterone Registry number: EC 1.14.13.- Synonym: 19-hydroxysteroid hydroxylase, deoxycorticosterone 11-19-hydroxylase (26 Jun 1999) |
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