| TSC | Thiazide-sensitive Na-Cl contransporter |
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| diuretics, thiazide | Diuretics characterised as analogs of 1,2,4-benzothiadiazine-1,1-dioxide. All have a common mechanism of action and differ primarily in the dose required to produce a given effect. They act directly on the kidney to increase the excretion of sodium chloride and water and also increase excretion of potassium ions. (12 Dec 1998) |
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| thiazide | <pharmacology> A group of medications that cause diuresis (loss of water through the kidney). They are frequently used to treat high blood pressure and congestive heart failure. Thiazides can cause low blood potassium levels if dietary potassium or (a potassium supplement) is not taken. Thiazides include hydrochlorothiazide, methyclothiazide, chlorthalidone, bendroflumethiazide, hydroflumethiazide, polythiazide, trichlormethiazide and chlorothiazide. (27 Sep 1997) |
| thiazide diabetes | Impaired carbohydrate metabolism associated with the use of thiazide diuretic drugs; severe manifestations are seen in persons having diabetes mellitus, but impairment is mild or absent in nondiabetic individuals. (05 Mar 2000) |
| -thiazide |
any of a group of drugs commonly used as diuretics in the treatment of hypertension; they block the reabsorption of sodium in the kidneys
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