| cell-free system | <cell culture, molecular biology> Any system in which a normal cellular reaction is reconstituted in the absence of cells for example in vitro translation systems that will synthesise protein from mRNA using a lysate of rabbit reticulocytes or wheat germ. A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (12 Dec 1998) |
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| renal portal system | An arterial portal system, in which efferent glomerular arterioles receive blood from the capillaries of the renal glomeruli and carry it to the peritubular capillary plexus surrounding the proximal and distal convoluted tubules. Synonym: hypothalamohypophysial portal system. (05 Mar 2000) |
| p blood-group system | A blood group related to the abo, lewis and I systems. at least five different erythrocyte antigens are possible, some very rare, others almost universal. Multiple alleles are involved in this blood group. (12 Dec 1998) |
| renin-angiotensin-aldosterone system | The hormones, renin, angiotensin, and aldosterone work together to regulate blood pressure. A sustained fall in blood pressure causes the kidney to release renin. This is converted to angiotensin in the circulation. Angiotensin then raises blood pressure directly by arteriolar constriction and stimulates adrenal gland to produce aldosterone which promotes sodium and water retention by kidney, such that blood volume and blood pressure increase. (05 Mar 2000) |
| renin-angiotensin system | <physiology> A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming angiotensin I. The converting enzyme contained in the lung acts on angiotensin I in the plasma converting it to angiotensin II, the most powerful directly pressor substance known. It causes contraction of the arteriolar smooth muscle and has other indirect actions mediated through the adrenal cortex. (25 Jun 1999) |
| centimeter-gram-second system | The scientific system of expressing the fundamental physical units of length, mass, and time, and those units derived from them, in centimeters, grams, and seconds; currently being replaced by the International System of Units based on the meter, kilogram, and second. (05 Mar 2000) |
| reproductive system | In women, the organs that are directly involved in producing eggs and in conceiving and carrying babies. (12 Dec 1998) |
| pedal system | Efferent fibres connecting the forebrain with more caudal structures. (05 Mar 2000) |
| central nervous system | <anatomy, neurology> Pertaining to the brain, cranial nerves and spinal cord. It does not include muscles or peripheral nerves. In invertebrates, the central nervous system is composed of the segmental ganglia of the ventral nerve cord together with the fused ganglia or brain at the anterior end. Acronym: CNS (12 Jan 1998) |
| central nervous system agents | A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "non-specific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with non-specific mechanisms are generally further classed according to whether they produce behavioural depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (12 Dec 1998) |
| central nervous system depressants | A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anaesthetics, hypnotics and sedatives, narcotics, and tranquillising agents (antipsychotics and antianxiety agents). (12 Dec 1998) |
| central nervous system infections | Diseases of the central nervous sytem collectively, caused by pathogenic organisms. (12 Dec 1998) |
| central nervous system neoplasms | Neoplasms located in the brain, spinal cord, or meninges. (12 Dec 1998) |
| central nervous system stimulants | A loosely defined group of drugs that tend to increase behavioural alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (12 Dec 1998) |
| glycogen debranching enzyme system | 1,4-alpha-d-glucan-1,4-alpha-d-glucan 4-alpha-d-glucosyltransferase/dextrin 6 alpha-d-glucanohydrolase. An enzyme system having both 4-alpha-glucanotransferase (ec 2.4.1.25) and amylo-1,6-glucosidase (ec 3.2.1.33) activities. As a transferase it transfers a segment of a 1,4-alpha-d-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-d-glucan. As a glucosidase it catalyses the endohydrolysis of 1,6-alpha-d-glucoside linkages at points of branching in chains of 1,4-linked alpha-d-glucose residues. Amylo-1,6-glucosidase activity is deficient in glycogen storage disease type III. (12 Dec 1998) |