| deficiency anaemia | Any anaemia resulting from a dietary deficiency of materials essential to red blood cell formation, e.g., iron, vitamins (especially folic acid), protein. Synonym: deficiency anaemia. (05 Mar 2000) |
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| Diamond-Blackfan anaemia | Congenital nonregenerative, familial hypoplastic, or pure red cell anaemia; erythrogenesis imperfecta; Diamond-Blackfan syndrome; autosomal recessive normocytic normochromic anaemia resulting from congenital hypoplasia of the bone marrow, which is grossly deficient in erythroid precursors while other elements are normal; anaemia is progressive and severe, but leukocyte and platelet counts are normal or slightly reduced; survival of transfused erythrocytes is normal; minor congenital anomalies are found in some patients. Synonym: congenital nonregenerative anaemia, Diamond-Blackfan anaemia, Diamond-Blackfan syndrome, erythrogenesis imperfecta, familial hypoplastic anaemia, pure red cell anaemia. (05 Mar 2000) |
| dilution anaemia | <medicine> An abnormally watery state of the blood; anaemia. Origin: NL, fr. Gr. "ydwr water + blood. Source: Websters Dictionary (01 Mar 1998) |
| dimorphic anaemia | Anaemia in which two distinct forms of red cells are circulating. (05 Mar 2000) |
| diphyllobothrium anaemia | A rare form of macrocytic anaemia associated with Diphyllobothrium latum infection, especially in Finland. Synonym: fish tapeworm anaemia. (05 Mar 2000) |
| drepanocytic anaemia | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| icterohemolytic anaemia | <haematology> A hereditary disorder that leads to a chronic haemolytic anaemia due to an abnormality in the red blood cell membrane. This disorder is caused by a defective gene. Red cells are resistant to stress and rupture easily. Infants may appear jaundiced and pale. Fatigue, weakness and shortness of breath are other symptoms that may be seen in older patients. The spleen may also be enlarged. Treatment includes splenectomy (removal of the spleen). After this is accomplished the life-span of the red blood cells returns to normal. (27 Sep 1997) |
| dyshemopoietic anaemia | Any anaemia resulting from defective function of the bone marrow. (05 Mar 2000) |
| infectious anaemia | Anaemia developing as a complication of infection; probably results from depressed formation and short survival of erythrocytes and abnormal iron metabolism. (05 Mar 2000) |
| infectious anaemia virus, equine | A species of lentivirus, subgenus equine lentiviruses (lentiviruses, equine), causing acute and chronic infection in horses. It is transmitted mechanically by biting flies, mosquitoes, and midges, and iatrogenically through unsterilised equipment. Chronic infection often consists of acute episodes with remissions. (12 Dec 1998) |
| intertropical anaemia | An obsolete term for anaemia occurring in hookworm disease, chiefly necatoriasis. (05 Mar 2000) |
| iron deficiency anaemia | Hypochromic microcytic anaemia characterised by low serum iron, increased serum iron-binding capacity, decreased serum ferritin, and decreased marrow iron stores. Synonym: hypoferric anaemia. (05 Mar 2000) |
| isochromic anaemia | Any anaemia in which the concentration of haemoglobin in the erythrocytes is within the normal range, i.e., the mean corpuscular haemoglobin concentration is from 32 to 36%. Synonym: isochromic anaemia. (05 Mar 2000) |
| osteosclerotic anaemia | Anaemia due to compromise of erythropoiesis due to osteosclerosis. (05 Mar 2000) |
| ovalocytic anaemia | Anaemia characterised by elliptical erythrocytes (ovalocytes) resembling those observed normally in camels; 1 to 15% of erythrocytes in nonanaemic persons may be oval, but greater proportions are observed in certain patients with microcytic anaemia. See: elliptocytosis. Synonym: cameloid anaemia, ovalocytic anaemia. (05 Mar 2000) |