| transcriptional control | <molecular biology> Control of gene expression by controlling the number of RNA transcripts of a region of DNA. A major regulatory mechanism for differential control of protein synthesis in both pro and eukaryotic cells. (18 Nov 1997) |
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| translational control | <molecular biology> The control of protein synthesis by regulation of the translation step, for example by selective usage of preformed mRNA or instability of the mRNA. (18 Nov 1997) |
| facility regulation and control | Formal voluntary or governmental procedures and standards required of hospitals and health or other facilities to improve operating efficiency, and for the protection of the consumer. (12 Dec 1998) |
| feedback control | The regulation of the activity of an enzyme by one of its products. (09 Oct 1997) |
| feedforward control | The process in which one of the products of a metabolic pathway induces an enzyme which participates in the metabolic pathway to act. (09 Oct 1997) |
| forms and records control | A management function in which standards and guidelines are developed for the developing, maintaining, and handling of forms and records. (12 Dec 1998) |
| locus control region | A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed to regulate transcription by opening and remodeling chromatin structure. It may also have enhancer activity. (12 Dec 1998) |
| locus of control | A theoretical construct designed to assess a person's perceived control over his/her own behaviour; classified as internal if the person feels in control of events, external if others are perceived to have that control. (05 Mar 2000) |
| allelic gene | See: allele, dominance of traits. (05 Mar 2000) |
| antibiotic resistance gene | Genes in a microorganism which confer resistance to antibiotics, for example by coding for enzymes which destroy it, by coding for surface proteins which prevent it from entering the microorganism, or by being a mutant form of the antibiotic's target so that it can ignore it. (09 Oct 1997) |
| autosomal gene | A gene located on any chromosome other than the sex chromosomes (X or Y). (05 Mar 2000) |
| bicoid gene | A group of genes which are important to the proper development of the head and thorax in the embryo of the fruit fly Drosophila melanogaster. (09 Oct 1997) |
| BRCA1 breast cancer susceptibility gene | This mutated (changed) version of the BRCA1 gene makes a person susceptible to developing breast cancer. (12 Dec 1998) |
| calcitonin gene-related peptide | <protein> A second product transcribed from the calcitonin gene. Calcitonin gene related peptide is found in a number of tissues including nervous tissue. It is a vasodilator that may participate in the cutaneous triple response. It is a neuropeptide of 37 amino acids with structural homology to salmon calcitonin. Co-localises with substance P in neurons. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator. Intracerebral administration leads to a rise in noradrenergic sympathetic outflow, a rise in blood pressure and a fall in gastric secretion. Acronym: CGRP (05 May 2002) |
| cancer susceptibility gene | tumour suppressor gene |