| lacunar state | The presence of lacunes in the brain. One of the major factors underlying cerebrovascular disease; high correlation with hypertension and atherosclerosis. Symptomatic forms include pure motor hemiplegia and pure hemisensory syndrome; multiple lacunar infarcts are the most common cause of pseudobulbar palsy. (05 Mar 2000) |
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| local excitatory state | Increased irritability of a nerve fibre or muscle fibre which is produced by an ineffective electrical stimulus; summation of the stimuli may occur, resulting in a propagated impulse if two or more subliminal stimuli are applied in rapid succession. (05 Mar 2000) |