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phosphoglyceracetals Generic term for glycerophospholipids in which the glycerol moiety bears a 1-alkenyl ether group (on rarer occasions, a 1-alkyl ether group); e.g., alk-1-enylglycerophospholipid; plasmalogens synthesis is reduced in disorders of the peroxisome.
Synonym: phosphoglyceracetals.
(05 Mar 2000)
phosphoglycerate <biochemistry> The molecules 2 phosphoglycerate and 3 phosphoglycerate are intermediates in glycolysis. 3 phosphoglycerate is the precursor for synthesis of phosphatidic acid and diacyl glycerol, hence of phosphatidyl phospholipids.
(31 Dec 1997)
phosphoglycerate dehydrogenase <enzyme> Catalyses the oxidation of 3-phosphoglyceric acid to 3-phosphohydroxy pyruvate, which can be transaminated and then hydrolyzed to give serine; minor descriptor (75-85); on-line and index medicus search alcohol oxidoreductases (75-77) and carbohydrate dehydrogenases (78-85)
Registry number: EC 1.1.1.95
Synonym: phosphoglycerate oxidoreductase, 3-phosphoglycerate-nad+ 2-oxidoreductase, 3-phosphoglycerate dehydrogenase, sera gene product
(26 Jun 1999)
phosphoglycerate kinase <enzyme> An enzyme catalyzing the transfer of a phosphate group from 3-phospho-d-glycerate in the presence of ATP to yield 3-phospho-d-glyceroyl phosphate and ADP.
Chemical name: ATP-3-phospho-D-glycerate 1-phosphotransferase
Registry number: EC 2.7.2.3
(12 Dec 1998)
phosphoglycerate mutase <enzyme> An enzyme that catalyses the conversion of 2-phospho-d-glycerate to 3-phospho-d-glycerate.
Chemical name: D-Phosphoglycerate 2,3-phosphomutase
Registry number: EC 5.4.2.1
(12 Dec 1998)
phosphoglycerate permease <chemical>
(26 Jun 1999)
phosphoglyceric acid 1. HOCH2-CH(OH)CO-OPO3H2; glyceroyl phosphoric acid; glyceroyl phosphate;an acid anhydride between glyceric acid and phosphoric acid.
2. HOCH2-CH(OPO3H2) COOH; 2-phosphoglyceric acid;the deprotonated form, 2-phosphoglycerate, is an intermediate in glycolysis.
3. H2O3POCH2-CH (OH)COOH; 3-phosphoglyceric acid;the deprotonated form, 3-phosphoglycerate, is an intermediate in glycolysis.
(05 Mar 2000)
phosphoglycerides Acylglycerol and diacylglycerol phosphates;constituents of nerve tissue, and involved in fat transport and storage.
(05 Mar 2000)
phosphoglyceromutase An isomerizing enzyme catalyzing the reversible interconversion of 2-phosphoglycerate and 3-phosphoglycerate with 2,3-bisphosphoglycerate present as a cofactor; a deficiency of this enzyme, which plays a role in glycolysis, is an inherited disorder that results in an intolerance for strenuous exercise.
(05 Mar 2000)
phosphoheptose isomerase <enzyme> Sedoheptulose-7-p is converted to d-glycero-d-manno-heptulose
Registry number: EC 5.3.1.-
(26 Jun 1999)
phosphohexokinase <enzyme> An enzyme that catalyses the conversion of a nucleotide triphosphate and a sugar phosphate to a nucleotide diphosphate and a sugar diphosphate. D-fructose 6-phosphate, d-tagatose 6-phosphate, and sedoheptulose 7-phosphate can act as acceptors; ATP, utp, ctp, and itp can act as donors. A deficiency of this enzyme is the cause of glycogen storage disease type vii.
Chemical name: ATP:D-fructose-6-phosphate 6-phosphotransferase
Registry number: EC 2.7.1.11
(12 Dec 1998)
phosphohexomutase <enzyme> An enzyme that catalyses the reversible interconversion of d-fructose 6-phosphate and d-glucose-6-phosphate; a part of glycolysis and gluconeogenesis; glucosephosphate isomerase deficiency is an inherited disorder resulting in liver glycogenesis and haemolytic anaemia.
Synonym: hexosephosphate isomerase, phosphohexomutase, phosphohexose isomerase.
(05 Mar 2000)
phosphohexose isomerase <enzyme> An enzyme that catalyses the reversible interconversion of d-fructose 6-phosphate and d-glucose-6-phosphate; a part of glycolysis and gluconeogenesis; glucosephosphate isomerase deficiency is an inherited disorder resulting in liver glycogenesis and haemolytic anaemia.
Synonym: hexosephosphate isomerase, phosphohexomutase, phosphohexose isomerase.
(05 Mar 2000)
phosphohexose isomerase deficiency <enzyme> An enzyme deficiency characterised by chronic nonspherocytic haemolytic anaemia; autosomal recessive inheritance.
Synonym: phosphohexose isomerase deficiency.
(05 Mar 2000)
phosphohydrolases Phosphoric monoester hydrolases;enzymes (EC sub-subclass 3.1.3) cleaving phosphoric acid (as orthophosphate) from its esters; trivial names usually end in phosphate.
(05 Mar 2000)
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