| ras protein geranylgeranyltransferase | <enzyme> Mammalian enzyme transfers geranylgeranyl groups to a cysteine residue fourth from the c-terminal group of a p21 ras protein, prefers leucine at the cooh terminus; see also rhoa geranylgeranyltransferase and protein geranylgeranyltransferase Registry number: EC 2.5.1.- Synonym: geranylgeranyltransferase ras protein, ras protein gg transferase, ggtase I, caax geranylgeranyl transferase (26 Jun 1999) |
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| gene regulatory protein | <molecular biology> Any protein that interacts with DNA sequences of a gene and controls its transcription. (18 Nov 1997) |
| rec A protein | <protein> A protein (40 kD) product of the rec (recombination) gene, that catalyses the pairing of a single stranded piece of DNA with its complementary sequence, displacing a loop of single stranded DNA (D loop). It catalyses the ATP-driven exchange of DNA strands in genetic recombination. The product of the reaction consists of a duplex and a displaced single-stranded loop which has the shape of the letter d and is therefore called a d-loop structure. ATP is hydrolyzed to ADP during the reaction; also has proteolytic activity. (22 Sep 2002) |
| rec B protein | <protein> Protein (140 kD), one subunit of nuclease that unwinds double stranded DNA and fragments the strands sequentially, the other subunit is recC (128 kD) (18 Nov 1997) |
| receptor protein | An intracellular protein (or protein fraction) that has a high specific affinity for binding a known stimulus to cellular activity, such as a steroid hormone or adenosine 3',5'-cyclic phosphate. (05 Mar 2000) |
| receptor protein-tyrosine kinase | <enzyme> A catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of receptors. Many growth and differentiation factor receptors contain this domain. It is critical for the signal transduction pathways required for mitogenesis, transformation, and cell differentiation. Registry number: EC 2.7.1.- (12 Dec 1998) |
| parathyroid hormonelike protein | A 140 amino acid protein secreted by some cancer cells; it causes hypercalcaemia. (05 Mar 2000) |
| carrier protein | <protein> A protein which transports specific substances through the cell membrane in which it is embedded and into the cell. Different carrier proteins are required to transport different substances, as each one is designed to recognise only one substance, or group of similar substances. (09 Oct 1997) |
| catabolite gene activator protein | <molecular biology, protein> A regulatory protein that triggers the transcription of genes that generate the enzymes bacteria need to usenutrients when glucose isabsent. (16 Mar 1998) |
| catabolite (gene) activator protein | A protein that can be activated by cAMP, whereupon it affects the action of RNA polymerase by binding it with it or near it on the DNA to be transcribed. Synonym: cAMP receptor protein, catabolite gene activator. (05 Mar 2000) |
| matrix Gla protein | A calcium binding protein. (05 Mar 2000) |
| cationic protein | <biochemistry> Proteins of azurophil granules of neutrophils, rich in arginine. A chymotrypsin like protease found in azurophil granules is also very cationic as is cathepsin G and neutrophil elastase. Eosinophil cationic protein (21 kD) is particularly important because it damages schistosomula in vitro. (16 Mar 1998) |
| MCK1 protein kinase | <enzyme> From saccharomyces cerevisiae; involved in transcriptional activation of ime1, stimulation of spore maturation, and facilitation of centromere activity during mitosis; member of the glycogen synthase kinase 3 family; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: meiosis and centromere regulatory kinase, ypk1 phosphotyrosyl protein, ypk1 kinase, mck1 gene product (26 Jun 1999) |
| pat1 protein kinase | <enzyme> Negatively regulated by mei3+ gene product Registry number: EC 2.7.1.- Synonym: ran1 protein (26 Jun 1999) |
| glial fibrillary acidic protein | <protein> This protein, found in microfilaments of glial cells, helps distinguish glial from nonglial tumours. A laboratory stain is used to test for its presence. (16 Dec 1997) |