| Kaposi sarcoma | <oncology, tumour> A sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumour that results in multifocal purplish coloured papules or plaques that eventually form nodules. Usually classed as an angioblastic tumour. Seen most commonly in patients who suffer from AIDS. Tumours may also occur within the intestines and lungs. Diagnosis may be confirmed with skin biopsy or upper GI endoscopy. Radiation therapy, cryotherapy and chemotherapy have all been used in the treatment of Kaposi sarcoma. (27 Sep 1997) |
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| Kaposi sarcoma associated herpesvirus protease | <enzyme> Genbank af010430 Registry number: EC 3.4.21.- Synonym: kshv protease, human herpesvirus 8 protease (26 Jun 1999) |
| kaposi's sarcoma | <oncology, tumour> A type of vascular cancer characterised by soft purple nodules that usually develop first on the feet and then slowly spread across the skin.This cancer is most often found in people with compromised immune systems, such as AIDS patients. (09 Oct 1997) |
| fascicular sarcoma | <tumour> A malignant neoplasm, believed to be of mesenchymal origin, composed of elongated, spindle-shaped cells. Synonym: fascicular sarcoma. (05 Mar 2000) |
| undifferentiated sarcoma of liver | <radiology> Kiddies, age 4 - 15 yrs, M = F, complex hepatic mass, often hypovascular, most in right lobe, large ( more than 10 cm), ** Differential diagnosis: embryonal rhabdomyosarcoma (12 Dec 1998) |
| Kirsten sarcoma virus | <virology> A murine sarcoma inducing retrovirus, generated by passaging a murine erythoblastosis virus in newborn rats. Source of the Ki ras oncogene. (18 Nov 1997) |
| feline sarcoma | <oncology, tumour> An oncogene carried by one of the strains of the feline sarcoma virus (the Snyder-Theilen strain, Garden-Rasheed strain, McDonough strain). It causes the development of sarcoma tumours in cats. The normal product of the gene (as a proto-oncogene) seems to be a kinase enzyme that phosphorylates (attaches phosphate groups to) the amino acid tyrosine in polypeptides. (09 Oct 1997) |
| feline sarcoma virus | <virology> A retrovirus which carries an oncogene that causes feline sarcoma (a tumour-causing disease) in cats. (09 Oct 1997) |
| leukocytic sarcoma | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
| lymphatic sarcoma | <tumour> Obsolete term for lymphosarcoma. (05 Mar 2000) |
| aberrant complex | An anomalous electrocardiographic complex, more specifically an abnormal ventricular complex caused by abnormal intraventricular conduction of a supraventricular impulse. (05 Mar 2000) |
| activated complex | <chemistry> State of highest energy during a reaction. When reactants form the activated complex, bond breaking and bond formation is occurring. Synonym: transition state. (09 Jan 1998) |
| AIDS dementia complex | <immunology> A frequent cerebral condition in people with AIDS that results in the loss of cognitive capacity, affecting the ability to function in a social or occupational setting. Its cause has not been determined exactly, but may result from HIV infection of cells in the brain or an inflammatory reaction to such infection. (09 Oct 1997) |
| aids-related complex | A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating aids-related complex (arc) from aids include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in aids; follicular or mixed hyperplasia in arc lymph nodes, leading to lymphocyte degeneration and depletion more typical of aids; evolving succession of histopathological lesions such as localization of kaposi's sarcoma, signaling the transition to the full-blown aids. (12 Dec 1998) |
| alpha-keto acid dehydrogenase complex | See: alpha-keto acid dehydrogenase. Anaerobic dehydrogenase, an enzyme (usually a pyridinoenzyme) catalyzing the transfer of hydrogen from some metabolite to some acceptor molecule (e.g., NAD+, cytochrome) other than oxygen; e.g., lactate dehydrogenase's, isocitrate dehydrogenase's, and others in EC class 1, excluding those listed under aerobic dehydrogenase. (05 Mar 2000) |