| extracellular matrix proteins | Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., collagen, elastin, fibronectins and laminin). (12 Dec 1998) |
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| extrinsic proteins | Pathways that can be easily removed from a biomembrane (e.g., by altering the pH or the ionic strength). Synonym: extrinsic proteins. (05 Mar 2000) |
| UBC proteins | <protein> Family of proteins involved in conjugating ubiquitin to proteins. UBC1, UBC4 and UBC5 have a role in targeting proteins for degradation, but others have more complex roles, including an involvement in cell cycle control (UBC3) and the secretory pathway (UBC6). (18 Nov 1997) |
| kazal proteins | <molecular biology> Family of serine protease inhibitors. Includes seminal acrosin inhibitors, pancreatic secretory trypsin inhibitor (PSTI), Bdellin B 3 from leech. (18 Nov 1997) |
| fatty acid binding proteins | <biochemistry> Group of small cytosolic proteins that bind fatty acids or other organic solutes. (18 Nov 1997) |
| unwinding proteins | Enzymes that uncoil the DNA allowing recombination events to occur. (05 Mar 2000) |
| fungal proteins | Proteins found in any species of fungus. (12 Dec 1998) |
| fusion proteins, bcr-abl | Translation products of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukaemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukaemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in abelson murine leukaemia virus. (12 Dec 1998) |
| fusion proteins, gag-onc | General name for the translation products of a fusion mRNA consisting of a gag gene and a viral oncogene (v-onc). These products are thought to have the ability to transform cells. (12 Dec 1998) |
| fusion proteins, gag-pol | Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The polyprotein is synthesised only five percent of the time since pol is out of frame with gag, and is generated by ribosomal frameshifting. (12 Dec 1998) |
| luminescent proteins | Proteins which are involved in the phenomenon of light emission in living systems. Included are the "enzymatic" and "non-enzymatic" types of system with or without the presence of oxygen or co-factors. (12 Dec 1998) |