| U1 small nuclear RNA-(guanosine-N2)-methyltransferase | <enzyme> A trans-active non-small nuclear ribonucleoprotein; facilitates the formation of the m3g cap Registry number: EC 2.1.1.- Synonym: u1 snrna(g-n2)mtase (26 Jun 1999) |
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| U6 small nuclear RNA methyltransferase | <enzyme> Methylates gamma-phosphate residues in rnas; distinct from u6 snrna n6-adenosine methyltranferase; mw 130 kD; from hela cells Registry number: EC 2.1.1.- Synonym: u6 snrna capping enzyme (26 Jun 1999) |
| unilateral small kidney | <radiology> Scarred: reflux nephropathy, lobar infarction Cf: other urographic patterns smooth kidney: ischemia due to focal arterial disease, chronic infarction, radiation nephritis, congenital hypoplasia, post-obstructive atrophy, post-inflammatory atrophy, reflux atrophy Cf: other urographic patterns (12 Dec 1998) |
| follicular predominantly small cleaved cell lymphoma | <tumour> A B-cell lymphoma with nodular or diffuse lymph node or bone marrow involvement by large lymphoid cells. Synonym: follicular predominantly small cleaved cell lymphoma, nodular histiocytic lymphoma. (05 Mar 2000) |
| lymphoma, small-cell | A B-cell lymphoma presumably representing a tumour of interfollicular B-lymphocytes that may be functional. Those that are secrete identical immunoglobulin molecules. (12 Dec 1998) |
| lymphoma, small cleaved-cell, diffuse | An intermediate-grade malignant lymphoma in which the neoplastic cells (B-lymphocytes) exhibit variability in size, configuration, and degree of differentiation. The cells have distinctive nuclei, irregular in shape, with marked indentations and angularity. (12 Dec 1998) |
| lymphoma, small cleaved-cell, follicular | A low-grade malignant lymphoma of predominantly follicular pattern. Follicles are of relatively uniform size and shape and the cells are usually somewhat larger than normal lymphocytes. Nuclei are irregular with prominent indentations and cytoplasm can rarely be identified. Cells exhibiting these characteristics are often called centrocytes. (12 Dec 1998) |
| lymphoma, small lymphocytic | A low-grade malignant lymphoma that may, in some cases, be considered histologically identical to chronic lymphocytic leukaemia (cll; leukaemia, lymphocytic, chronic). It is diffuse in pattern, representing the neoplastic proliferation of well-differentiated B-lymphocytes. In patients with immunoglobulin gammopathies, the lymphocytes may exhibit plasmacytoid characteristics. (12 Dec 1998) |
| lymphoma, small noncleaved-cell | A high-grade malignant lymphoma that includes both burkitt tumour (burkitt lymphoma) and other lymphomas previously designated undifferentiated non-burkitt type. Nuclei in burkitt tumour are round to ovoid and uniform in size. The non-burkitt type exhibits greater nuclear variation and less evidence of cellular maturation with a correspondingly lesser degree of differentiation. (12 Dec 1998) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |
| acute disease | Disease having a short and relatively severe course. (12 Dec 1998) |