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immunologically activated cell An immunocyte that is in an elevated state of reactivity capable of carrying out an immune response, in contradistinction to an immunologically competent cell.
(05 Mar 2000)
immunologically competent cell A small lymphocyte capable of being immunologically activated by exposure to a substance that is antigenic (immunogenic) for the respective cell; activation involves either the capacity to produce antibody or the capacity to participate in cell-mediated immunity.
(05 Mar 2000)
immunologically privileged sites Sites where allografts are not readily rejected, probably because these particular areas have poor lymphatic drainage.
(05 Mar 2000)
immunologist <specialist> A specialist practiced in the treatment of allergic disease and those disease processes that involve dysfunction of the immune system.
(27 Sep 1997)
immunology <study> A subfield of biology that deals with the study of antigens and the immuneprocess and how humans and higher animals fight off disease.
(09 Oct 1997)
immunomagnetic separation A cell-separation technique where magnetizable microspheres or beads are first coated with monoclonal antibody, allowed to search and bind to target cells, and are then selectively removed when passed through a magnetic field. Among other applications, the technique is commonly used to remove tumour cells from the marrow of patients who are to undergo autologous bone marrow transplantation.
(12 Dec 1998)
immunomodulator <immunology> A drug such as interleukin-2 that alters, suppresses or strengthens the bodys immune system.
(09 Oct 1997)
immunomodulatory 1. Capable of modifying or regulating one or more immune functions.
2. An immunological adjustment, regulation, or potentiation.
(05 Mar 2000)
immunopathology <study> A branch of medicine that deals with the study of how the body fights offdisease and the study of immunodeficiencydiseases.
(09 Oct 1997)
immunoperoxidase Analogous to indirect fluorescent antibody in that antibody presence is identified on antigenic substrates visually. However, in the indirect immunoperoxidase instead of fluorescent dye-antibody conjugates, enzyme-antibody conjugates (principally peroxidase enzymes) are reacted with their corresponding substrates to produce a product which can be seen with a light microscope, eliminating the requirement for costly fluorescent microscopic equipment.
(05 Mar 2000)
immunoperoxidase technique An immunologic test that utilises antibodies chemically conjugated to the enzyme peroxidase.
(05 Mar 2000)
immunophenotyping Process of classifying cells of the immune system based on structural and functional differences. The process is commonly used to analyze and sort T-lymphocytes into subsets based on CD antigens by the technique of flow cytometry.
(12 Dec 1998)
immunophilin <protein> Generic term for intracellular protein that binds immunosuppressive drugs such as cyclosporin, FK506, rapamycin.
Both cyclophilin and the receptor for FK506 are peptidyl prolyl cis trans isomerases rotamases). Immunophilins are thought to interact with calcineurin.
(18 Nov 1997)
immunopotentiation Enhancement of the immune response by increasing its rate or prolonging its duration.
(05 Mar 2000)
immunopotentiator Any of a wide variety of specific or non-specific substances which on inoculation enhances or augments an immune response.
(05 Mar 2000)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 9
  • Immunoglobulin lambda-Chains - »õâ One of the types of light chain subunits of the immunoglobulins with a molecular weight of approximately 22 kDa.
    Synonyms : Immunoglobulin lambda-Chain, lambda-1-Immunoglobulin, lambda-2-Immunoglobulin, lambda-Chain Immunoglobulins, lambda-Immunoglobulin Light Chain, lambda-Immunoglobulin Light Chains, lambda-x Immunoglobulin, Chains, lambda-Immunoglobulin Light
  • Immunoglobulin Light Chains - »õâ Polypeptide chains, consisting of 211 to 217 amino acid residues and having a molecular weight of approximately 22 kDa. There are two major types of light chains, kappa and lambda. Two Ig light chains and two Ig heavy chains (IMMUNOGLOBULIN HEAVY CHAINS) make one immunoglobulin molecule.
    Synonyms : Immunoglobulin Light Chain, Immunoglobulin Light-Chain, Light-Chain Immunoglobulins, Chains, Immunoglobulin Light, Immunoglobulins, Light Chain, Light Chain Immunoglobulins, Light Chain, Immunoglobulin, Light Chains, Immunoglobulin, Light-Chain, Immunoglobulin
  • Immunoglobulin M - »õâ A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.
    Synonyms : IgM1, IgM2, 19S Gamma Globulin
  • Immunoglobulin mu-Chains - »õâ The class of heavy chains found in IMMUNOGLOBULIN M. They have a molecular weight of approximately 72 kDa and they contain about 57 amino acid residues arranged in five domains and have more oligosaccharide branches and a higher carbohydrate content than the heavy chains of IMMUNOGLOBULIN G.
    Synonyms : Immunoglobulin mu-Chain, mu Immunoglobulin Heavy Chain, mu Immunoglobulin Heavy Chains, mu-Chain Immunoglobulins, Immunoglobulin mu Chain, Immunoglobulin mu Chains, Immunoglobulins, mu Chain, mu Chain Immunoglobulins, mu-Chain, Immunoglobulin
  • Immunoglobulin Subunits - »õâ The PROTEIN SUBUNITS of the multimeric IMMUNOGLOBULIN proteins, such as IGA; IGD; IGE; IGG; and IGM. Included are the heavy and light chains which contain the specific ANTIGEN binding domains, as well as the accessory proteins that are part of the the secreted forms of IGM and IGA; (SECRETORY IGA).
    Synonyms : Ig Polypeptide Chains, Ig Subunit, Ig Subunits, Immunoglobulin Chains, Immunoglobulin Polypeptide Chains, Subunit, Ig, Subunits, Ig
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immunosuppression Suppression of the body's immune system and its ability to fight infections or disease. Immunosuppression may be deliberately induced with drugs, as in preparation for bone marrow or other organ transplantation to prevent rejection of the donor tissue. It may also result from certain diseases such as AIDS or lymphoma or from anticancer drugs.
Ãâó: www.stjude.org/glossary
immunoassay A test that uses the binding of antibodies to antigens to identify and measure certain substances. Immunoassays may be used to diagnose disease. Also, test results can provide information about a disease that may help in planning treatment (for example, when estrogen receptors are measured in breast cancer).
Ãâó: www.stjude.org/glossary
immunocompetence The ability to produce a normal immune response.
Ãâó: www.stjude.org/glossary
immunocompromised Having a weakened immune system caused by certain diseases or treatments.
Ãâó: www.stjude.org/glossary
immunodeficiency The decreased ability of the body to fight infection and disease.
Ãâó: www.stjude.org/glossary
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