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idiosyncratic sensitivity A type I allergic reaction (atopic).
(05 Mar 2000)
idiot-prodigy A person of low general intelligence who possesses an unusual faculty in performing certain mental tasks of which most normal persons are incapable.
Synonym: idiot-prodigy.
Origin: Fr.
(05 Mar 2000)
idiot-savant A person of low general intelligence who possesses an unusual faculty in performing certain mental tasks of which most normal persons are incapable.
Synonym: idiot-prodigy.
Origin: Fr.
(05 Mar 2000)
idiotope An antigenic determinant (epitope) unique to a single clone of cells and located in the variable region of the immunoglobulin product of that clone or to the T-cell receptor. The idiotope forms part of the antigen binding site. Any single immunoglobulin may have more than one idiotope. Idiotopes are also associated with the antigen binding sites of T-cell receptors. They are the epitopes to which an anti-idiotype antibody or T-cell binds.
(18 Nov 1997)
idiotroph A commercially-grown fungi or bacterium that has suffered a mutation that renders it unable to synthesise the substances for which it has beencultured.
(09 Oct 1997)
idiotrophic Capable of choosing its own food.
Origin: idio-+ G. Trophe, food
(05 Mar 2000)
idiotropic Turning inward upon one's self.
Origin: idio-+ G. Trope, a turning
(05 Mar 2000)
idiotype The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts.
(18 Nov 1997)
idiotype antibody <immunology> An antibody directed against the antigen specific part of the sequence of an antibody or T-cell receptor and thus recognise the binding sites of other antibodies.
In principle an anti-idiotype antibody should inhibit a specific immune response and they are important to the regulation of the immune system.
(13 Nov 1997)
idiotype autoantibody <immunology> An autoantibody, the specificity of which is directed against one of one's own idiotypes.
See: anti-idiotype antibody.
Synonym: idiotype autoantibody.
(05 Mar 2000)
idiotypic antigenic determinant The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts.
(18 Nov 1997)
idioventricular Pertaining to or associated with the cardiac ventricles alone.
(05 Mar 2000)
idioventricular rhythm A slow independent ventricular rhythm under control of a ventricular centre (which is, by definition, ectopic).
Synonym: ventricular rhythm.
(05 Mar 2000)
iditol <biochemistry> Reduction product of the hexose idose.
(05 Mar 2000)
iditol dehydrogenase <enzyme> An alcohol oxidoreductase which catalyses the oxidation of l- or d-iditol to l- or d-sorbose in the presence of NAD. Acts also on glucitol to form fructose and on other closely related sugar alcohols.
Chemical name: L-Iditol:NAD+ 2-oxidoreductase
Registry number: EC 1.1.1.14
(12 Dec 1998)
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