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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 9
  • Complement C5b - »õâ The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.
    Synonyms : C5b Complement, Complement 5b, Complement Component 5b, C5b, Complement, Complement, C5b, Component 5b, Complement
  • Complement C6 - »õâ A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
    Synonyms : C6 Complement, Complement 6, Complement Component 6, C6, Complement, Complement, C6, Component 6, Complement
  • Complement C7 - »õâ A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of MEMBRANE ATTACK COMPLEX; C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7 which is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9.
    Synonyms : C7 Complement, Complement 7, Complement Component 7, C7, Complement, Complement, C7, Component 7, Complement
  • Complement C8 - »õâ A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.
    Synonyms : C8 Complement, Complement 8, Complement Component 8, Complement Component C8 alpha, Complement Component C8 alpha Chain, Complement Component C8 beta, Complement Component C8 beta Chain, Complement Component C8 gamma, Complement Component C8 gamma Chain
  • Complement C9 - »õâ A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
    Synonyms : C9 Complement, Complement 9, Complement Component 9, C9, Complement, Complement, C9, Component 9, Complement
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 9
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