| PDGFbetaR | Platelet-derived growth factor beta receptor |
|---|---|
| PDGFR-alpha | Platelet-derived growth factor receptor alpha |
| PDGFRbeta | Platelet-derived growth factor receptor beta |
| VEGFR-3 | Vascular Endothelial Growth Factor Receptor-3 |
| VEGFR-2 | Vascular endothelial growth factor receptor-2 |
| T-cell receptor | <immunology> The antigen recognising receptor on the surface of T-cells. Heterodimeric (disulphide linked), one of the immunoglobulin superfamily of proteins, binds antigen in association with the major histocompatibility complex (MHC), leading to the activation of the cell. There are two subunits (_ and _, 42-44 kD in mouse, 50-40 kD in humans), each with variable and constant regions, that are associated noncovalently with T3 (20-30 kD). A second heterodimer on CD3 cells with _ (35 kD in mice, 55 kD in humans) and _ (45 kD in mice, 40 kD in humans) chains is a second T-cell antigen receptor that is not MHC restricted. The __ T-cell receptors (TCRs) are formed on very early T-cells in the thymus. (18 Nov 1997) |
|---|---|
| TCK receptor-tyrosine kinase | <enzyme> A member of the eph receptor tyrosine kinase subfamily; expressed during xenopus development; shows 79% amino acid identity to hek2; genbank l43621 Registry number: EC 2.7.1.- Synonym: tck protein (26 Jun 1999) |
| TGF-beta receptor protein kinase | <enzyme> Belongs to the receptor-type serine-threonine kinase subfamily; from chick embryo, related to type II receptor for tgf-beta; 502 aa residues, mw 56,766 da; aa sequence given in first source Registry number: EC 2.7.1.- Synonym: tgf-beta rpk, rpk-1, rpk-2 (26 Jun 1999) |
| early receptor potential | A voltage arising across the eye from a charge displacement within photoreceptor pigment, in response to an intense flash of light. (05 Mar 2000) |
| thyroid receptor antibody | A test that measures the amount of an antibody (thyroid stimulating antibody) which is directed against a receptor for TSH on the thyroid gland. This antibody acts like TSH and stimulates the thyroid to produce excessive amounts of thyroid hormone. The presence of this antibody generally indicates Grave's disease (hyperthyroidism). (27 Sep 1997) |
| TIE-2 receptor tyrosine kinase | <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source Registry number: EC 2.7.10.- Synonym: tie-2-rtk (26 Jun 1999) |
| tie receptor tyrosine kinase | <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known Registry number: EC 2.7.10.- Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk (26 Jun 1999) |
| endothelin receptor | Simple squamous epithelium lining blood vessels, lymphatics and other fluid filled cavities (such as the anterior chamber of the eye). Mesodermally derived, unlike most epithelia. (18 Nov 1997) |
| estradiol receptor tyrosine kinase | <enzyme> Calcium and calmodulin dependent Registry number: EC 2.7.1.- Synonym: ertk (26 Jun 1999) |
| kainate receptor | A type of glutamate receptor that participates in excitatory neurotransmission and also binds kainate and acts as a cation channel; injection of kainate causes death of neurons but preserves glial cells and axons. (05 Mar 2000) |
| Fc receptor | Receptors present on a variety of cells for the Fc fragment of immunoglobulins. These receptors recognise immunoglobulins of the IgG and IgE class. (05 Mar 2000) |
| laminin receptor | A receptor found in many cell types that binds laminin and has a role in cell attachment and neurite outgrowth. (05 Mar 2000) |
| L-AP4 receptor | A type of glutamate receptor that also binds a particular synthetic agonist and acts as a cation channel. (05 Mar 2000) |
| LDL receptor disorder | Abnormality in clearance of LDL from the plasma due to abnormality in LDL receptor activity; causes hypercholesterolaemia. (05 Mar 2000) |
| leukocyte tyrosine kinase receptor tyrosine kinase | <enzyme> May be receptor for pre-b lymphocyte growth or differentiation factor; aa sequence given in first source Registry number: EC 2.7.1.- Synonym: ltk receptor tyrosine kinase, ltk receptor tk, ltk protein, leukocyte tyrosine kinase (ltk) (26 Jun 1999) |