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phosphates Inorganic salts of phosphoric acid.
(12 Dec 1998)
phosphatic <chemistry> Pertaining to, or containing, phosphorus, phosphoric acid, or phosphates; as, phosphatic nodules.
<medicine> Phosphatic diathesis, a habit of body which leads to the undue excretion of phosphates with the urine.
Source: Websters Dictionary
(01 Mar 1998)
phosphatidal Older trivial name for alk-1-enylglycerophospholipid.
(05 Mar 2000)
phosphatidase <enzyme> An enzyme that catalyses the hydrolysis of a lecithin to a lysolecithin by removing the 2-acyl group; also acts on other phospholipids by removing a fatty acid from the 2-position; this enzyme has an important role in prostaglandin and leukotriene biosynthesis.
Synonym: lecithinase A, phosphatidase, phosphatidolipase.
(05 Mar 2000)
phosphatidate A salt or ester of a phosphatidic acid.
Phosphatidate phosphatase, an enzyme that catalyses the hydrolysis of phosphatidate producing inorganic phosphate and 1,2-diacylglycerol; this enzyme participates in phospholipid and triacylglycerol metabolism.
(05 Mar 2000)
phosphatidate phosphatase <enzyme> A phosphomonoesterase involved in the synthesis of triacylglycerols. It catalyses the hydrolysis of phosphatidates with the formation of diacylglycerols and orthophosphate.
Chemical name: 3-sn-Phosphatidate phosphohydrolase
Registry number: EC 3.1.3.4
(12 Dec 1998)
phosphatide <biochemistry> The family of phospholipids based on 1,2 diacyl 3 phosphoglyceric acid.
(31 Dec 1997)
phosphatidic acid <biochemistry> The parent structure for phosphatidyl phospholipids, present in low concentrations in membranes. The acyl groups are derived from long chain fatty acids.
An intermediate in the synthesis of diacyl glycerol, the immediate precursor of most of the phosphatidyl phospholipids (except phosphatidyl inositol) and of triacyl glycerols.
(31 Dec 1997)
phosphatidic acid kinase <enzyme> Plant enzyme which converts phosphatidic acid to diacylglycerol pyrophosphate
Registry number: EC 2.7.4.-
(26 Jun 1999)
phosphatidic acids Fatty acid derivatives of glycerophosphates. They are composed of glycerol bound in ester linkage with 1 mole of phosphoric acid at the terminal 3-hydroxyl group and with 2 moles of fatty acids at the other two hydroxyl groups.
(12 Dec 1998)
phosphatidolipase <enzyme> An enzyme that catalyses the hydrolysis of a lecithin to a lysolecithin by removing the 2-acyl group; also acts on other phospholipids by removing a fatty acid from the 2-position; this enzyme has an important role in prostaglandin and leukotriene biosynthesis.
Synonym: lecithinase A, phosphatidase, phosphatidolipase.
(05 Mar 2000)
phosphatidyl The radical of a phosphatidic acid; e.g., phosphatidylcholine.
(05 Mar 2000)
phosphatidylcholine <biochemistry> The major phospholipid of most mammalian cell membranes where the 1 acyl residue is normally saturated and the 2 acyl residue unsaturated.
Choline is attached to phosphatidic acid by a phosphodiester linkage. Major synthetic route is from diacyl glycerol and CDP choline. Forms monolayers at an air water interface and forms bilayer structures (liposomes) if dispersed in aqueous medium. A zwitterion over a wide pH range. Readily hydrolysed in dilute alkali.
(31 Dec 1997)
phosphatidylcholine-ceramide phosphocholine transferase <enzyme> Cdpcholine is not a donor; imvolved in sphingomyelin synthesis
Registry number: EC 2.7.8.-
Synonym: pc-cer-pch transferase, sphingomyelin synthase
(26 Jun 1999)
phosphatidylcholine-sterol o-acyltransferase <enzyme> An enzyme secreted from the liver into the plasma of many mammalian species. It catalyses the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the c-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma.
Chemical name: Phosphatidylcholine:sterol O-acyltransferase
Registry number: EC 2.3.1.43
(12 Dec 1998)
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