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phenylaceturic acid C6H5CH2CO-NH-CH2COOH;an end product of the metabolism of phenylated fatty acids with even numbers of carbon atoms.
Synonym: phenylaceturic acid.
(05 Mar 2000)
phenylacetylurea An anticonvulsant used in the treatment of epilepsy.
Synonym: phenylacetylurea.
(05 Mar 2000)
phenylacrylic acid C6H5CH==CHCOOH; 3-phenylpropenoic acid;obtained from cinnamon oil, Peruvian and tolu balsams, or storax. It has been used in lupus as paint and in infectious diseases to promote leukocytosis.
Synonym: cinnamylic acid, phenylacrylic acid.
(05 Mar 2000)
phenylacrylic acid decarboxylase <enzyme> Confers resistance to phenylacrylic acids in yeasts; enzyme from bacillus pumilus catalyses nonoxidative conversion of ferulic acid and p-coumaric acid to 4-vinylguaiacol and 4-vinylphenol, respectively; amino acid sequence in first source
Registry number: EC 4.1.1.-
Synonym: cinnamic acid decarboxylase, ferulate decarboxylase, pad1 gene product, ferulic acid decarboxylase, 4-coumarate decarboylase, p-coumarate decarboxylase
(26 Jun 1999)
phenylalaninase Phenylalanine 4-monooxygenase.
(05 Mar 2000)
phenylalanine <amino acid> One of the amino acids which the body cannot manufacture itself, but must acquire from food. It is abundant in meats and cheese.
Phenylalanine is a precursor of tyrosine and together they lead to the formation of thyroxine or thyroid hormone and of adrenaline and noradrenaline which is converted into a neurotransmitter, a brain chemical which transmits nerve impulses. This neurotransmitter is used by the brain to manufacture noradrenaline which promotes mental alertness, memory, elevates mood and suppresses the appetite very effectively.
Along with another amino acid, tryptophan, phenylalanine governs the release of an intestinal hormone called cholecystokinin.
Overuse of phenylalanine supplements can cause anxiety, headaches and hypertension and are contraindicated for pregnant woman, those who suffer from anxiety attacks, high blood pressure, PKU, pigmented melanoma or anyone taking an anti-depressant containing monoamine oxidase inhibitors.
(15 Oct 1997)
phenylalanine 4-hydroxylase <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria.
Synonym: phenylalanine 4-hydroxylase.
(05 Mar 2000)
phenylalanine 4-monooxygenase <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria.
Synonym: phenylalanine 4-hydroxylase.
(05 Mar 2000)
phenylalanine aminopeptidase <enzyme> Metalloenzyme from legionella pneumophila; mw: 35,000; pH optimum 8-9.5
Registry number: EC 3.4.11.-
(26 Jun 1999)
phenylalanine ammonia lyase <enzyme> An enzyme that catalyses the deamination of l-phenylalanine to form trans-cinnamate and ammonia. It may also act on l-tyrosine. Since the enzyme deprives neoplastic tissue of phenylalanine, it has been used experimentally in the treatment of acute lymphoblastic leukaemia. The enzyme is obtained from many plants and is used as an enzymic marker for lignification and other developmental processes in plant cells.
Pharmacological action: antineoplastic agent.
Chemical name: L-Phenylalanine ammonia-lyase
Registry number: EC 4.3.1.5
(12 Dec 1998)
phenylalanine hydroxylase <enzyme> An enzyme of the oxidoreductase class that catalyses the reaction l-phenylalanine, tetrahydrobiopterin, and oxygen to yield l-tyrosine, dihydrobiopterin, and water, the reaction synthesizing tyrosine from phenylalanine.
Chemical name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
Registry number: EC 1.14.16.1
(12 Dec 1998)
phenylalanine hydroxylase phosphatase <enzyme> Catalyses dephosphorylation of phosphorylated phenylalanine hydroxylase
Registry number: EC 3.1.3.-
Synonym: phe hydroxylase phosphatase
(26 Jun 1999)
phenylalanine oxidase <enzyme> Forms phenylpyruvate in the presence of air; consider also phenylalanine dehydrogenase (nad) which requires nad
Registry number: EC 1.4.3.-
Synonym: phenylalanine desaminase, l-phenylalanine oxidase, phenylalanine dehydrogenase
(26 Jun 1999)
phenylalanine-trna ligase <enzyme> An enzyme that activates phenylalanine with its specific transfer RNA.
Chemical name: Phenylalanine:tRNA(Phe) ligase (AMP-forming)
Registry number: EC 6.1.1.20
(12 Dec 1998)
phenylalanyl chain A polypeptide component of insulin containing 30 amino acyl residues, beginning with a phenylalanyl residue (NH2-terminus); insulin is formed by the linkage of a B chain to an A chain by two disulfide bonds; the amino-acid composition of the B chain is a function of species.
Synonym: phenylalanyl chain.
(05 Mar 2000)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 9
  • Phenylbutazone - »õâ A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this disease. (From AMA Drug Evaluations Annual, 1994, p1822)
    Synonyms : Butacote, Butadion, Butadione, Butapirazol, Butapyrazole, Butazolidin
  • Phenylbutyrates - »õâ
    Synonyms :
  • Phenylcarbamates - »õâ Phenyl esters of carbamic acid or of N-substituted carbamic acids. Structures are similar to PHENYLUREA COMPOUNDS with a carbamate in place of the urea.
    Synonyms : Phenyl-Carbamates, Phenyl Carbamates
  • Phenylenediamines - »õâ
    Synonyms :
  • Phenylephrine - »õâ An alpha-adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
    Synonyms : (R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol, Metaoxedrin, Metasympatol, Mezaton, Neo-Synephrine, Neosynephrine, Phenylephrine Hydrochloride, Phenylephrine Tannate, Neo Synephrine, Tannate, Phenylephrine
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phenomenology Phenomenology is a current in philosophy that takes intuitive experience of phenomena (what presents itself to us in conscious experience) as its starting point and tries to extract the essential features of experiences and the essence of what we experience. It stems from the School of Brentano and was mostly based on the work of the 20th century philosopher Edmund Husserl, and was developed further by Maurice Merleau-Ponty and Martin Heidegger. ...
Ãâó: en.wikipedia.org/wiki/Phenomenology
phenotype The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. Phenotype is determined to some extent by genotype, or by the identity of the alleles that an individual carries at one or more positions on the chromosomes. Many phenotypes are determined by multiple genes and influenced by environmental factors. ...
Ãâó: en.wikipedia.org/wiki/Phenotype
phenyl The terms phenyl and phenol, along with benzene and benzyl, are explained and compared on the page The phenyl group -- and related terms.
Ãâó: www.geocities.com/Athens/Thebes/5118/obc/402gloss....
phenol The terms phenyl and phenol, along with benzene and benzyl, are explained and compared on the page The phenyl group -- and related terms.
Ãâó: www.geocities.com/Athens/Thebes/5118/obc/402gloss....
phenotype The overall attributes of an organism arising due to the interaction of its genotype with the environment.
Ãâó: www.geocities.com/templarser/complexglos.html
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