| NOTT | nocturnal oxygen therapy trial |
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| PREDICT | Prospective Randomized Evaluation of Diltiazem CD Trial |
| PRT | Penicillium roqueforti toxin; pharmaceutical research and testing; phosphoribosyl transferase; posto... |
| RDB | random double-blind [trial] |
| RTC | random control trial; rape treatment center; renal tubular cell; residential treatment center; retur... |
| clinical thermometer | A small, self-registering thermometer, consisting of a simple scaled glass tube containing mercury, used for taking the temperature of the body. (05 Mar 2000) |
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| clinical trials | Medical research studies conducted with volunteers. Each study is designed to answer scientific questions and to find better ways to prevent, detect, or treat cancer. (12 Dec 1998) |
| clinical trials, phase I | Studies performed to evaluate the safety of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques in healthy subjects and to determine the safe dosage range (if appropriate). These tests also are used to determine pharmacologic and pharmacokinetic properties (toxicity, metabolism, absorption, elimination, and preferred route of administration). They involve a small number of persons and usually last about 1 year. This concept includes phase I studies conducted both in the u.s. And in other countries. (12 Dec 1998) |
| clinical trials, phase II | Studies that are usually controlled to assess the effectiveness and dosage (if appropriate) of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques. These studies are performed on several hundred volunteers, including a limited number of patients with the target disease or disorder, and last about two years. This concept includes phase II studies conducted in both the u.s. And in other countries. (12 Dec 1998) |
| clinical trials, phase III | Comparative studies to verify the effectiveness of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques determined in phase II studies. During these trials, patients are monitored closely by physicians to identify any adverse reactions from long-term use. These studies are performed on groups of patients large enough to identify clinically significant responses and usually last about three years. This concept includes phase III studies conducted in both the u.s. And in other countries. (12 Dec 1998) |
| clinical trials, phase IV | Planned post-marketing studies of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques that have been approved for general sale. These studies are often conducted to obtain additional data about the safety and efficacy of a product. This concept includes phase IV studies conducted in both the u.s. And in other countries. (12 Dec 1998) |
| controlled clinical trials | Clinical trials involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicines, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trials are characterised as randomised controlled trials. However, trials employing treatment allocation methods such as coin flips, odd-even numbers, patient social security numbers, days of the week, medical record numbers, or other such pseudo- or quasi-random processes, are simply designated as controlled clinical trials. (12 Dec 1998) |
| cytogenetics, clinical | The application of cytogenetics to clinical medicine. For example, clinical cytogenetic studies might be done to determine whether a child with possible Down syndrome has an extra chromosome 21. (12 Dec 1998) |
| psychology, clinical | The branch of psychology concerned with psychological methods of recognizing and treating behaviour disorders. (12 Dec 1998) |
| decision support systems, clinical | Computer-based information systems used to integrate clinical and patient information and provide support for decision-making in patient care. (12 Dec 1998) |
| disease, clinical | A disease with clinical signs and symptoms that can be recognised. As distinct from a subclinical illness without recognizable clinical manifestations. Diabetes, for example, can be subclinical in a person before emerging as a clinical disease. (12 Dec 1998) |
| in clinical parlance | The term often refers to the posterior funiculus of the spinal cord. (05 Mar 2000) |
| epidemiology, clinical | Epidemiology focused specifically upon patients. (12 Dec 1998) |
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