| HYD | extinct large sirenian mammal formerly found near Asiatic coast of the Bering Sea |
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| HYD | a diuretic drug (trade name Esidrix and HydroDIURIL) used in the treatment of hypertension |
| HYD | (physics) of or relating to hydrodynamics |
| HYD | study of fluids in motion |
| HYD | of or relating to or used in the production of electricity by waterpower |
| HYD | turbine consisting of a large and efficient version of a water wheel used to drive an electric generator |
| HYD | electricity produced by water power |
| HYD | diuretic used to treat hypertension and edema |
| HYD | a weak poisonous liquid acid |
| HYD | an unstable poisonous corrosive acid know primarily in the form of its salts |
| HYD | a speedboat that is equipped with hydrofoils that lift it so that it skims the water at high speeds |
| HYD | a device consisting of a flat or curved piece (as a metal plate) so that its surface reacts to the water it is passing through |