| Hoffmann's muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
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| pulp atrophy | Diminution in size and/or cellular elements of the dental pulp due to interference with the blood supply. (05 Mar 2000) |
| horizontal atrophy | A progressive loss of alveolar and supporting bone surrounding the teeth, beginning at the most coronal level of the bone. Synonym: horizontal resorption. (05 Mar 2000) |
| senile atrophy | Wasting of tissues and organs with advancing age from decreased catabolic or anabolic processes, at times due to endocrine changes, decreased use, or ischemia. Synonym: geromarasmus. (05 Mar 2000) |
| serous atrophy | A degenerative change occurring in fat cells, the fat being absorbed and its place being taken by a serous fluid. (05 Mar 2000) |
| Hunt's atrophy | An obsolete term for atrophy of the small muscles of the hand without sensory disturbances; two types are recognised: thenar, from compression of the thenar branch of the median nerve; hypothenar, from compression of the deep palmar branch of the ulnar nerve. (05 Mar 2000) |
| spinal muscular atrophy | <radiology> 2nd most common autosomal recessive disease in Caucasians, pathology, degeneration of the spinal anterior horn cells, atrophy and wasting of skeletal muscles, types, SMA I = Werdnig-Hoffman disease: rapidly progressive, SMA II = intermediate form, SMA III = Kugelberg-Welander disease: slowly progressive, uncommon adult forms, usual presentations, floppy baby, arthrogryposis, muscle weakness in infancy, diagnosis, weakness and wasting with areflexia, electrophysiology shows anterior horm cell disease, genetics, linked to chromosome 5q., neuronal apoptosis inhibitory protein (NAIP) gene, survival motor neuron (SMN) gene (12 Dec 1998) |
| neuritic atrophy | Abnormalities of the skin, hair, nails, subcutaneous tissues and bone, caused by peripheral nerve lesions. Synonym: neuritic atrophy, neurogenic atrophy, neurotrophic atrophy, trophic changes. (05 Mar 2000) |
| neurogenic atrophy | Abnormalities of the skin, hair, nails, subcutaneous tissues and bone, caused by peripheral nerve lesions. Synonym: neuritic atrophy, neurogenic atrophy, neurotrophic atrophy, trophic changes. (05 Mar 2000) |
| neurotrophic atrophy | Abnormalities of the skin, hair, nails, subcutaneous tissues and bone, caused by peripheral nerve lesions. Synonym: neuritic atrophy, neurogenic atrophy, neurotrophic atrophy, trophic changes. (05 Mar 2000) |
| striate atrophy of skin | Bands of thin wrinkled skin, initially red but becoming purple and white, which occur commonly on the abdomen, buttocks, and thighs at puberty and/or during and following pregnancy, and result from atrophy of the dermis and overextension of the skin; also associated with ascites and Cushing's syndrome. Synonym: atrophoderma striatum, lineae albicantes, lineae atrophicae, linear atrophy, stretch marks, stria, striae atrophicae, striate atrophy of skin, traction atrophy, vergeture. (05 Mar 2000) |
| Sudeck's atrophy | Atrophy of bones, commonly of the carpal or tarsal bones, following a slight injury such as a sprain. See: causalgia, reflex sympathetic dystrophy. Synonym: acute reflex bone atrophy, posttraumatic osteoporosis, Sudeck's syndrome. Origin: L. English sweat (05 Mar 2000) |
| nutritional type cerebellar atrophy | A restricted type of cerebellar cortical degeneration, affecting particularly the Purkinje cells of the anterior and superior vermis; probably caused by thiamin deficiency; most frequently seen in chronic alcoholics and then called alcoholic cerebellar degeneration. (05 Mar 2000) |
| dentatorubral cerebellar atrophy with polymyoclonus | A familial disorder beginning in late childhood, characterised by progressive cerebellar ataxia, action myoclonus and preserved intellect. Probably due to multiple causes, mitochondrial abnormalities being one. Synonym: dentatorubral cerebellar atrophy with polymyoclonus. (05 Mar 2000) |
| disuse atrophy | Muscle wasting caused by immobilization, such as casting. (05 Mar 2000) |