| NO synthase | <enzyme> An enzyme that catalyses the conversion of l-arginine, NADPH, and oxygen to citrulline, nitric oxide, and NADP+. The enzyme found in brain, but not that induced in lung or liver by endotoxin, requires calcium.There are two isoforms, one constitutive and one activated by calmodulin. Chemical name: L-Arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) Registry number: EC 1.14.13.39 Acronym: NOS (12 Dec 1998) |
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| d-aminolevulinic acid synthase | <enzyme> An enzyme that catalyses the reaction of succinyl-CoA with glycine to form d-aminolevulinic acid, coenzyme A, and CO2. The committed step in porphyrin biosynthesis. Acronym: ALA (05 Mar 2000) |
| daunorubicin-doxorubicin polyketide synthase | <chemical> Required for doxorubicin biosynthesis; involved in the selection of propionyl-CoA as the starter unit to the formation of a decaketide and its cyclization to an aklanonic acid to the formation of doxorubicin; genbank l35560 Synonym: dnr-dxr pks, doxorubicin polyketide synthase, dxr pks, dps gene product (26 Jun 1999) |
| dehydrosqualene synthase | <enzyme> Involved in the synthesis of yellow carotenoid 4,4'-diaponeurosporene in staphylococcus aureus; 254 amino acids, mw 30 kD; amino acid sequence given in first source (orf1); genbank x73889 Registry number: EC 1.3.- Synonym: crtm protein, crtm gene product (26 Jun 1999) |
| delta(1)-tetrahydrocannabinolic acid synthase | <enzyme> Catalyses the oxidocyclization of cannabigerolic acid without requiring molecular oxygen, coenzymes, or cofactors; n-terminal amino acid sequence given in first source Registry number: EC 5.3.- Synonym: delta(1)-thca synthase (26 Jun 1999) |
| delta-cadinene synthase | <enzyme> Catalyses conversion of farnesylpyrophosphate to (+)-delta-cadinene; isolated from cotton. Registry number: EC 5.- (26 Jun 1999) |
| deoxyhypusine synthase | <enzyme> Catalyses the transfer of the 4-aminobutyl moiety from spermidine to the epsilon amino group of a specific lysine residue Registry number: EC 1.5.1.- Synonym: spermidine dehydrogenase (nad, l-deoxyhypusyl-forming) (26 Jun 1999) |
| deoxyxylulose-5-phosphate synthase | <enzyme> Catalyses thiamin diphosphate-dependent acyloin condensation between pyruvate and glyceraldehyde Registry number: EC 2.2.1.- Synonym: dxp synthase (26 Jun 1999) |
| synthase | Trivial name used in Enzyme Commission Report for a lyase reaction going in the reverse direction (NTP-independent). For individual synthase's, see the specific names. See: synthetase. (05 Mar 2000) |
| diglucosyldiacylglycerol synthase | <enzyme> Catalyses formation of major, lamellar-forming diglucosyldiacylglycerol from major, nonlamellar-prone monoglucosyldiacylglycerol; isolated from acholeplasma laidlawii Registry number: EC 2.4.1.- Synonym: diglucosyl diacylglycerol synthase, dglcdag synthase (26 Jun 1999) |
| dihydropteroate synthase | <enzyme> An enzyme that catalyses the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. Chemical name: 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase Registry number: EC 2.5.1.15 (12 Dec 1998) |
| divinyl ether synthase | <enzyme> Catalyses conversion of hydroperoxides to divinyl ethers; isolated from garlic bulbs allium sativum; preferentially acts sterospecifically on the (s) enantomer of 13-hpod ((9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid Registry number: EC 1.- (26 Jun 1999) |
| D-myo-inositol-3-phosphate synthase | <enzyme> Catalyses conversion of d-glucose-6-phosphate to d-myo-inositol-3-phosphate Registry number: EC 5.5.1.- Synonym: inositol-3-phosphate synthase, ins3p synthase (26 Jun 1999) |
| dTDP-D-glucose synthase | <enzyme> Catalyses the formation of dtdp-d-glucose by using glucose-1-phosphate and dttp as substrates; rfba is a dual function enzyme; rfba is also a phosphomannose isomerase-guanosine diphosphomannose pyrophosphorylase; see record of pmi-GMP Registry number: EC 2.7.7.- Synonym: rfba protein, deltatdp-glucose synthase, tyla1 gene product, rfba gene product (26 Jun 1999) |
| dTDP-L-rhamnose synthase | <enzyme> Catalyses the formation of dtdp-l-rhamnose by using rhamnose-1-phosphate and dttp as substrates; rfbd is a putative oxidoreductase Registry number: EC 2.7.7.- Synonym: rfbd protein, rfbd gene product (26 Jun 1999) |