| extrinsic proteins | Pathways that can be easily removed from a biomembrane (e.g., by altering the pH or the ionic strength). Synonym: extrinsic proteins. (05 Mar 2000) |
|---|---|
| UBC proteins | <protein> Family of proteins involved in conjugating ubiquitin to proteins. UBC1, UBC4 and UBC5 have a role in targeting proteins for degradation, but others have more complex roles, including an involvement in cell cycle control (UBC3) and the secretory pathway (UBC6). (18 Nov 1997) |
| kazal proteins | <molecular biology> Family of serine protease inhibitors. Includes seminal acrosin inhibitors, pancreatic secretory trypsin inhibitor (PSTI), Bdellin B 3 from leech. (18 Nov 1997) |
| fatty acid binding proteins | <biochemistry> Group of small cytosolic proteins that bind fatty acids or other organic solutes. (18 Nov 1997) |
| unwinding proteins | Enzymes that uncoil the DNA allowing recombination events to occur. (05 Mar 2000) |
| fungal proteins | Proteins found in any species of fungus. (12 Dec 1998) |
| fusion proteins, bcr-abl | Translation products of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukaemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukaemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in abelson murine leukaemia virus. (12 Dec 1998) |
| fusion proteins, gag-onc | General name for the translation products of a fusion mRNA consisting of a gag gene and a viral oncogene (v-onc). These products are thought to have the ability to transform cells. (12 Dec 1998) |
| fusion proteins, gag-pol | Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The polyprotein is synthesised only five percent of the time since pol is out of frame with gag, and is generated by ribosomal frameshifting. (12 Dec 1998) |
| luminescent proteins | Proteins which are involved in the phenomenon of light emission in living systems. Included are the "enzymatic" and "non-enzymatic" types of system with or without the presence of oxygen or co-factors. (12 Dec 1998) |
| acrocephalosyndactyly type 1 | <paediatrics> An inherited disease (autosomal dominant) or a spontaneously occurring disease characterised by a peaked head and unusual facial appearance, due to the premature closure of the cranial sutures. A skull X-ray can confirm the diagnosis and treatment is surgical. Inheritance: autosomal dominant. (27 Sep 1997) |
| Alzheimer type I astrocyte | Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy. (05 Mar 2000) |
| Alzheimer type II astrocyte | Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease. (05 Mar 2000) |
| American Type Culture Collection | <cell culture> A key resource for cultured cells, located in Rockville, USA. (12 Dec 1998) |
| Antoni type A neurilemoma | <tumour> Relatively solid or compact arrangement of neoplastic tissue that consists of Schwann cells arranged in twisting bundles and associated with delicate reticulin fibres; the nuclei of the Schwann cells are frequently grouped in parallel rows (so-called palisades), and the nuclei and fibres sometimes form exaggerated tactile corpuscles, called Verocay bodies. (05 Mar 2000) |