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adenosine 3',5'-cyclic monophosphate An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known.
Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate.
Acronym: cAMP
(05 Mar 2000)
adenosine 3',5'-cyclic phosphate phosphodiesterase <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine.
Synonym: cAMP phosphodiesterase.
(05 Mar 2000)
adenosine 3'-phosphate 3'-Adenylic acid.
See: adenylic acid.
(05 Mar 2000)
adenosine 3'-phosphate 5'-phosphosulfate 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H.
Synonym: active sulfate.
Acronym: PAPS
(05 Mar 2000)
adenosine 5'-diphosphate A condensation product of adenosine with pyrophosphoric acid, formed from ATP by the hydrolysis of the terminal phosphate group of the latter compound.
Acronym: ADP
(05 Mar 2000)
adenosine 5'-phosphate 5'-Adenylic acid.
See: adenylic acid.
(05 Mar 2000)
adenosine 5'-phosphoramidate hydrolase <enzyme> Hydrolyzes nucleoside 5'-monophosphoramidates into nucleoside 5'-phosphates and ammonia
Registry number: EC 3.9.1.-
Synonym: ampn hydrolase, nucleoside monophosphoramidate hydrolase
(26 Jun 1999)
adenosine 5'-phosphosulfate An intermediate in the formation of PAPS (active sulfate).
Adenosine 5'-phosphosulfate kinase, the enzyme that catalyses the formation of active sulfate from adenosine 5'-phosphosulfate and ATP.
Acronym: APS
(05 Mar 2000)
adenosine 5'-phosphosulfate sulfotransferase <enzyme> Catalyses transfer of sulfo group of adenylylsulfate to a carrier organic thiol, forming carrier-bound thiosulfate and AMP
Registry number: EC 2.8.2.-
Synonym: apsstase, aps sulfotransferase, adenylylsulfate sulfotransferase
(26 Jun 1999)
adenosine 5'-triphosphate Adenosinepyrophosphate;adenosine with triphosphoric acid esterfied at its 5' position; immediate precursors of adenine nucleotides in RNA. The primary energy currency of a cell.
Synonym: adenosine triphosphate.
Acronym: ATP
(05 Mar 2000)
adenosine cyclic phosphate An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known.
Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate.
Acronym: cAMP
(05 Mar 2000)
adenosine deaminase <enzyme> An enzyme that catalyses the hydrolysis of adenosine to inosine with the elimination of ammonia. Since there are wide tissue and species variations in the enzyme, it has been used as a tool in the study of human and animal genetics and in medical diagnosis.
Chemical name: Adenosine aminohydrolase
Registry number: EC 3.5.4.4
(12 Dec 1998)
adenosine diphosphate <biochemistry> ADP is used as an adenine, a ribose and a diphosphate unit.
(06 May 1997)
adenosine diphosphate glucose <chemical> Serves as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants.
Chemical name: Adenosine 5'-(trihydrogen diphosphate), P'-alpha-D-glucopyranosyl ester
(12 Dec 1998)
adenosine diphosphate ribose <chemical> Adenosine 5'-(trihydrogen diphosphate),5'-5-ester with d-ribose. An ester formed between the aldehydic carbon of ribose and the terminal phosphate of adenosine diphosphate. Serves as a ribose carrier.
Chemical name: Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose
(12 Dec 1998)
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