| thyroprotein | Synonym: thyroglobulin. 2. An iodinated protein, usually casein, that has thyroxine activity. (05 Mar 2000) |
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| thyroptosis | Downward dislocation of the thyroid gland. Origin: thyro-+ G. Ptosis, a falling (05 Mar 2000) |
| thyrostatic | <pharmacology> Antithyroid agent. (18 Nov 1997) |
| thyrotomy | <surgery> The operation of cutting into the thyroid cartilage. Origin: Thyro- + Gr. To cut. Source: Websters Dictionary (01 Mar 1998) |
| thyrotoxic | Denoting thyrotoxicosis. (05 Mar 2000) |
| thyrotoxic coma | Coma preceding death in severe hyperthyroidism, as in thyroid storm or thyrotoxic crisis. (05 Mar 2000) |
| thyrotoxic complement-fixation factor | A form of thyrotoxin; an antigen found most readily in thyroid tissue from thyrotoxic individuals; known to be chemically and immunologically distinct from thyroglobulin, and fixes complement when combined with antibody related to the gamma-globulin fraction of serum. With the exception of extremely small concentrations, the antigen is rarely found in normal glands or in diseased glands that are not associated with thyrotoxicosis; it is probably an intracellular substance (possibly a constituent of the "microsomal fraction"), and does not contain iodine in significant quantity. Not related to the complement-fixation reaction occurring with serum in Hashimoto's disease, in which the antigen is thyroglobulin. (05 Mar 2000) |
| thyrotoxic crisis | Thyroid crisis, the exacerbation of symptoms that occurs in severe thyrotoxicosis; can follow shock or injury or thyroidectomy; marked by rapid pulse (140 to 170 per minute), nausea, diarrhoea, fever, loss of weight, extreme nervousness, and a sudden rise in the metabolic rate; coma and death may occur; occasionally the entire clinical picture is that of profound prostration, weakness, and collapse, without the phase of muscular overactivity and tachycardia. Synonym: thyroid storm. (05 Mar 2000) |
| thyrotoxic encephalopathy | A metabolic encephalopathy arising in severe cases of thyrotoxicosis. (05 Mar 2000) |
| thyrotoxic heart disease | Cardiac symptoms, signs, and physiologic impairment due to overactivity of the thyroid gland usually due to excessive sympathetic stimulation. (05 Mar 2000) |
| thyrotoxic myopathy | Extreme muscular weakness in severe thyrotoxicosis affecting muscles of limbs and trunk as well as those used in speech and swallowing. (05 Mar 2000) |
| thyrotoxic serum | An antiserum obtained by injecting into animals the nucleoproteins of the thyroid gland. (05 Mar 2000) |
| thyrotoxicosis | <disease, endocrinology> The condition resulting from presentation to the tissues of excessive quantities of the thyroid hormones, whether the excess results from overproduction by the thyroid gland (as in Graves disease), originated outside the thyroid or is due to loss of storage function and leakage from the gland. (18 Nov 1997) |
| thyrotoxin | 1. A hypothetical substance formerly believed to be an abnormal product of diffusely hyperplastic thyroid glands in persons with Graves' disease, and presumed to be the cause of the distinctive signs and symptoms of that condition (in contrast to simple hyperthyroidism). 2. A complement-fixing antigenic factor associated with certain diseases of the thyroid gland. See: thyrotoxic complement-fixation factor. 3. Rarely used term referring to any material toxic to thyroidal tissue. (05 Mar 2000) |
| thyrotroph | A cell in the anterior lobe of the pituitary that produces thyrotropin. (05 Mar 2000) |