| tryptophan synthetase | <enzyme> An enzyme that catalyses the conversion of l-serine and 1-(indol-3-yl)glycerol 3-phosphate to l-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyses the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. Chemical name: L-Serine hydro-lyase (adding indoleglycerol-phosphate) Registry number: EC 4.2.1.20 (12 Dec 1998) |
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| tyrocidine synthetase | <enzyme> Consists of 3 multifunctional enzymes involved in the biosynthesis of the cyclic decapeptide tyrocidine; tyrocidine synthetase 1 activates the phenylalanine and racemises it; tyrocidine sythetase 2 activates proline, phenylalanine and phenylalanine in positions 2,3 and 4 and racemises phenylalanine at position 4; tyrocidine synthetase 3 catalyses the activation of the remaining 6 amino acids; see also record for tyrocidine synthetase 1 Registry number: EC 6.3.2.- Synonym: tycb gene product, tycc gene product (26 Jun 1999) |
| tyrosyl tRNA synthetase kinase | <enzyme> From postribosomal supernatants of bom:nmri mouse liver; comigrates with tyrosyl trna synthetase during several purification steps Registry number: EC 2.7.1.- Synonym: tyr trna synthetase kinase (26 Jun 1999) |
| F390 synthetase | <enzyme> From methanobacterium thermoautotrophicum; catalyses formation of f390 from ATP and coenzyme f420 Registry number: EC 2.7.7.- (26 Jun 1999) |
| kaurene synthetase | <enzyme> Catalyses conversion of all-trans-geranylgeranyl pyrophosphate to trans-copalyl pyrophosphate to kaurene Registry number: EC 2.5.1.- (26 Jun 1999) |
| fatty acid synthetase complex | <enzyme> Registry number: EC 6.- (12 Dec 1998) |
| fenchol synthetase | <enzyme> Catalyses cation-dependent cyclization of geranyl pyrophosphate and neryl pyrophosphate to the bicyclic rearranged endo-fenchol Registry number: EC 2.5.1.- Synonym: endo-fenchol synthetase (26 Jun 1999) |
| ferrichrome synthetase | <enzyme> Synthesises ferrichrome; from aspergillus quadricinctus Registry number: EC 6.3.2.- (26 Jun 1999) |
| kyotorphin synthetase | <enzyme> Found in brain synaptosomes; catalyses the formation of kyotorphin and pyrophosphate from tyrosine, arginine and ATP in the presence of mgcl2 Registry number: EC 6.3.2.- Synonym: tyrosine-arginine synthetase, tyr-arg synthetase (26 Jun 1999) |
| uroporphyrinogen I synthetase | <enzyme> An enzyme of haem biosynthesis that is defective in the inherited (autosomal dominant) disease, acute intermittent porphyria. UP I is isomerised to UP III by UP III synthetase, defective in the autosomal recessive disease, congenital erythropoietic porphyria. (18 Nov 1997) |
| flavanone synthetase | <enzyme> Forms naringenin and eriodictytol from malonyl-CoA and p-coumaroyl-CoA or malonyl-CoA + caffeoyl-CoA, respectively Registry number: EC 2.3.1.74 Synonym: chalcone synthase, narigenin-chalcone synthase (26 Jun 1999) |
| 10-formyltetrahydropteroyldiglutamic acid synthetase | <enzyme> Requires ATP; adds glutamate to 10-formyltetrahydropteroylglutamaic acid Registry number: EC 6.3.2.- Synonym: fhpdg synthetase, n(10)fh(4)pglu synthetase (26 Jun 1999) |
| 2',5'-oligoadenylate synthetase | <enzyme> An enzyme that catalyses the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (rnase l) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions. Registry number: EC 2.7.7.- (12 Dec 1998) |
| 3',5'-cyclic AMP synthetase | <enzyme> Enzyme responsible for the ATP. (06 May 1997) |
| 3-ketodihydrosphingosine synthetase | <enzyme> Serine and palmitoyl-CoA yields 3-ketodihydrosphingosine and co2 Registry number: EC 4.1.3.- (26 Jun 1999) |