| ADEE | age-dependent epileptic encephalopathy |
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| ADLC | antibody-dependent lymphocyte-mediated cytotoxicity |
| AFDC | Aid to Families with Dependent Children |
| BD | barbital-dependent; barbiturate dependence; base deficit; base of prism down; basophilic degeneratio... |
| BOLD | bleomycin, Oncovin, lomustin, dacarbazine; blood oxygenation level dependent |
| dependent drainage | Drainage from the lowest part and into a receptacle at a level lower than the structure being drained. Synonym: downward drainage. (05 Mar 2000) |
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| dependent oedema | A clinically detectable increase in extracellular fluid volume localised in a dependent area, as of a limb, characterised by swelling or pitting. (05 Mar 2000) |
| dependent personality | A personality in which a person passively allows others to assume responsibility for making decisions affecting him/her, characterised by a lack of self-confidence and an inability to function independently. (05 Mar 2000) |
| dependent personality disorder | An individual who fears separation and engaging othhers to assume responsibility (27 Sep 1997) |
| dependent variable | In experiments, a variable that is influenced by or dependent upon changes in the independent variable; e.g., the amount of a written passage retained (dependent variable) as a function of the different numbers of minutes (independent variable) allowed to study the passage. (05 Mar 2000) |
| diabetes mellitus, insulin-dependent | Diabetes mellitus characterised by insulin deficiency, sudden onset, severe hyperglycaemia, rapid progression to ketoacidosis, and death unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. (12 Dec 1998) |
| diabetes mellitus, non-insulin-dependent | Diabetes characterised by the ability to survive without ketoacidosis in the absence of insulin therapy. It is usually of slow onset and patients exhibit a tendency to obesity. (12 Dec 1998) |
| insulin dependent diabetes | A form of diabetes that requires the daily injection of the hormone insulin to maintain normal body chemistry. Avoidance of insulin in these patients will result in a severe metabolic derangement known as diabetic ketoacidosis. (27 Sep 1997) |
| insulin-dependent diabetes mellitus | A chronic condition in which the pancreas makes little or no insulin because the beta cells have been destroyed. The body is then not able to use the glucose (blood sugar) for energy. IDDM usually comes on abruptly, although the damage to the beta cells may begin much earlier. The signs of IDDM are a great thirst, hunger, a need to urinate often, and loss of weight. To treat the disease, the person must inject insulin, follow a diet plan, exercise daily, and test blood glucose several times a day. IDDM usually occurs in children and adults who are under age 30. This type of diabetes used to be known as juvenile diabetes, juvenile-onset diabetes, and ketosis-prone diabetes. (09 Oct 1997) |
| oxygen dependent killing | One of the most important bactericidal mechanisms of mammalian phagocytes involves the production of various toxic oxygen species (hydrogen peroxide, superoxide, singlet oxygen, hydroxyl radicals) through the metabolic burst. Although anaerobic killing is possible, the oxygen dependent mechanism is crucial for normal resistance to infection and a defect in this system is usually fatal within the first decade of life (chronic granulomatous disease). See: myeloperoxidase, chemiluminescence. (18 Nov 1997) |
| T-dependent antigen | An antigen that requires T helper cells in addition to appropriate B-cells. Most antigens are T-dependent. (05 Mar 2000) |
| thiol-dependent peroxidase | <enzyme> From giardia intestinalis, which lacks glutathione; enzyme can also act with exogenous glutathione Registry number: EC 1.11.1.- Synonym: glutathione-linked thiol peroxidase (26 Jun 1999) |
| thymus-dependent zone | <anatomy> Mid cortical region of lymph node, area that is particularly depleted of T lymphocytes in thymectomised animals and is referred to as the thymus dependent area. (18 Nov 1997) |
| 3-phosphoinositide-dependent protein kinase | <enzyme> Enzyme from rabbit skeletal muscle phosphorylates protein kinase b at thr308; activated by phosphatidylinositol 3,4,5-trisphosphate or phosphatidylinositol 3,4-bisphosphate Registry number: EC 2.7.10.- Synonym: pdk1 enzyme, ptdins(3,4,5)p3-dependent protein kinase-1 (26 Jun 1999) |
| L-glyceraldehyde 3-phosphate-NADPH-dependent oxidoreductase | <enzyme> Converts l-glyceraldehyde 3-phosphate to sn-glycerol 3-phosphate; does not act on d-glyceraldehyde 3-phosphate or dihydroxyacetone phosphate Registry number: EC 1.1.1.- Synonym: l-gap oxidoreductase (26 Jun 1999) |