| cystitis, interstitial | Disease that involves inflammation or irritation of the bladder wall. This inflammation can lead to scarring and stiffening of the bladder, and even ulcerations and bleeding. Diagnosis is based on symptoms, findings on cystoscopy and biopsy, and eliminating other treatable causes such as infection. Because doctors do not know what causes IC, treatments are aimed at relieving symptoms. most people are helped for variable periods of time by one or a combination of treatments. (12 Dec 1998) |
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| nephritis, interstitial | Primary or secondary disease of the renal interstitial tissue resulting from arterial, arteriolar, glomerular, or tubular disease which destroys individual nephrons, or from toxic involvement of interstitital cells and tubules due to systemic diseases such as gout, to drug exposure, or to mercury poisoning. Clinically it may be manifested primarily by loss of concentrating capacity, mineral wasting, proteinuria, and abnormal urine sediment. It may be seen in an acute form, particularly after specific bacterial infection, and may result in acute papillary necrosis. More commonly, the process is a chronic one with progressive renal atrophy and diminution of renal function. (12 Dec 1998) |
| desquamative interstitial pneumonia | Diffuse proliferation of alveolar epithelial cells, which desquamate into the air sacs and become filled with macrophages, accompanied by interstitial cellular infiltration and fibrosis; gradual onset of dyspnea and nonproductive cough occurs. (05 Mar 2000) |
| diffuse interstitial fibrosis | Progressive fibrous changes and scarring within the lung tissue, eventually interfering with normal gas exchange. (27 Sep 1997) |
| diffuse interstitial pulmonary fibrosis | This represents a group of pulmonary disorders (lower respiratory tract) that leads to a functional loss in the alveolar air sacs and a compromise in the diffusion of oxygen from air to blood. There is widespread inflammation and scar tissue (fibrosis) formation within the lung. The causes are varied and include: inorganic and organic dusts, gases, fumes, vapors, infections, radiation, medications, coal dust, silicosis and byssinosis. When the cause is not identifiable it is referred to as idiopathic diffuse interstitial pulmonary fibrosis (27 Sep 1997) |
| idiopathic interstitial fibrosis | A progressive inflammatory condition starting with diffuse alveolar damage and resulting in fibrosis and honeycombing over a variable time period; also a common feature of collagen-vascular diseases. Synonym: fibrosing alveolitis, Hamman-Rich syndrome, idiopathic interstitial fibrosis. (05 Mar 2000) |
| interstitial | <anatomy> Pertaining to or situated between parts or in the interspaces of a tissue. Origin: L. Interstitialis, inter = between, sistere = to set (18 Nov 1997) |
| interstitial absorption | The removal of water or of substances in the interstitial fluid by the lymphatics. (05 Mar 2000) |
| interstitial cell | 1. <plant biology> Cells lying between but distinct from other cells in a tissue, a good example being the interstitial cells in Hydra that serve as stem cells. 2. <pathology> Cells lying between the testis tubules of vertebrates and that are responsible for the secretion of testosterone. (18 Nov 1997) |
| interstitial cell-stimulating hormone | <protein> Synonym for luteinising hormone. (18 Nov 1997) |
| interstitial cell tumour of testis | <tumour> A small benign tumours of the testis that often produce testosterone, causing endocrine symptoms. Synonym: interstitial cell tumour of testis. (05 Mar 2000) |
| interstitial cystitis | <pathology, urology> A chronic inflammatory condition of the bladder. The cause of interstitial cystitis is unknown, but occurs more commonly in females. Symptoms include difficulty urinating, pain on urination, urinary urgency and increased frequency of urination. (27 Sep 1997) |
| interstitial deletion | Deletion that does not involve the terminal parts of a chromosome. (05 Mar 2000) |
| interstitial disease | A disease occurring chiefly in the connective-tissue framework of an organ, the parenchyma suffering secondarily. (05 Mar 2000) |
| interstitial emphysema | Presence of air in the pulmonary tissues consequent upon rupture of the air cells, presence of air or gas in the connective tissue. (05 Mar 2000) |