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phentolamine mesylate Phentolamine methanesulfonate;the same actions as phentolamine hydrochloride, for intravenous use only.
(05 Mar 2000)
phentolamine test A test for pheochromocytoma; intravenous administration of phentolamine (5 mg) reduces hypertension due to a pheochromocytoma but not that due to other causes, e.g., essential hypertension; the blood pressure is raised by the drug in the latter form of hypertension.
(05 Mar 2000)
phenyl <chemistry> A hydrocarbon radical (C6H5) regarded as the essential residue of benzene, and the basis of an immense number of aromatic derivatives.
<chemistry> Phenyl hydrate, a nitrogenous base (C6H5.N2H3) produced artificially as a colourless oil which unites with acids, ketones, etc, to form well-crystallized compounds.
Origin: Gr. To bring to light + -yl: cf. F. Phenyle. So called because it is a by-product of illuminating gas.
Source: Websters Dictionary
(01 Mar 1998)
phenyl alcohol <chemistry>
1. A white or pinkish crystalline substance, C6H5OH, produced by the destructive distillation of many organic bodies, as wood, coal, etc, and obtained from the heavy oil from coal tar.
It has a peculiar odour, somewhat resembling creosote, which is a complex mixture of phenol derivatives. It is of the type of alcohols, and is called also phenyl alcohol, but has acid properties, and hence is popularly called carbolic acid, and was formerly called phenic acid. It is a powerful caustic poison, and in dilute solution has been used as an antiseptic.
2. Any one of the series of hydroxyl derivatives of which phenol proper is the type.
<chemistry> Glacial phenol, any one of a series of compounds having both phenol and aldehyde properties. Phenol phthalein. See Phthalein.
Origin: Gr. To show + -ol: cf. F. Phenol.
Source: Websters Dictionary
(01 Mar 1998)
phenyl aminosalicylate P-aminosalicylic acid phenyl ester;an antituberculous drug.
Phenyl salicylate, the salicylic ester of phenol; the phenylic ester of salicylic acid; an intestinal analgesic and antipyretic; it has been used in the treatment of rheumatism, diarrhoea, and pharyngitis, as an enteric coating for tablets, and in ointments for sunburn prevention.
Synonym: salol.
(05 Mar 2000)
phenylacetaldehyde dehydrogenase <enzyme> From E coli; catalyses the oxidation of phenylacetaldehyde to phenylacetic acid in the presence of nad+
Registry number: EC 1.2.1.39
Synonym: phenylacetaldehyde-nad+ oxidoreductase
(26 Jun 1999)
phenylacetate - CoA ligase <enzyme> Catalyses the synthesis of phenylacetyl-CoA and phenoxyacetyl-CoA
Registry number: EC 6.2.1.30
Synonym: phenylacetyl-CoA ligase, phenylacetic acid activating enzyme, phenoxyacetic acid activating enzyme, phenacyl coenzyme a ligase, phenylacetate-CoA ligase (AMP-forming)
(26 Jun 1999)
phenylacetic acid C6H5CH2COOH;an abnormal product of phenylalanine catabolism, appearing in the urine in individuals with phenylketonuria.
(05 Mar 2000)
phenylaceturic acid C6H5CH2CO-NH-CH2COOH;an end product of the metabolism of phenylated fatty acids with even numbers of carbon atoms.
Synonym: phenylaceturic acid.
(05 Mar 2000)
phenylacetylurea An anticonvulsant used in the treatment of epilepsy.
Synonym: phenylacetylurea.
(05 Mar 2000)
phenylacrylic acid C6H5CH==CHCOOH; 3-phenylpropenoic acid;obtained from cinnamon oil, Peruvian and tolu balsams, or storax. It has been used in lupus as paint and in infectious diseases to promote leukocytosis.
Synonym: cinnamylic acid, phenylacrylic acid.
(05 Mar 2000)
phenylacrylic acid decarboxylase <enzyme> Confers resistance to phenylacrylic acids in yeasts; enzyme from bacillus pumilus catalyses nonoxidative conversion of ferulic acid and p-coumaric acid to 4-vinylguaiacol and 4-vinylphenol, respectively; amino acid sequence in first source
Registry number: EC 4.1.1.-
Synonym: cinnamic acid decarboxylase, ferulate decarboxylase, pad1 gene product, ferulic acid decarboxylase, 4-coumarate decarboylase, p-coumarate decarboxylase
(26 Jun 1999)
phenylalaninase Phenylalanine 4-monooxygenase.
(05 Mar 2000)
phenylalanine <amino acid> One of the amino acids which the body cannot manufacture itself, but must acquire from food. It is abundant in meats and cheese.
Phenylalanine is a precursor of tyrosine and together they lead to the formation of thyroxine or thyroid hormone and of adrenaline and noradrenaline which is converted into a neurotransmitter, a brain chemical which transmits nerve impulses. This neurotransmitter is used by the brain to manufacture noradrenaline which promotes mental alertness, memory, elevates mood and suppresses the appetite very effectively.
Along with another amino acid, tryptophan, phenylalanine governs the release of an intestinal hormone called cholecystokinin.
Overuse of phenylalanine supplements can cause anxiety, headaches and hypertension and are contraindicated for pregnant woman, those who suffer from anxiety attacks, high blood pressure, PKU, pigmented melanoma or anyone taking an anti-depressant containing monoamine oxidase inhibitors.
(15 Oct 1997)
phenylalanine 4-hydroxylase <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria.
Synonym: phenylalanine 4-hydroxylase.
(05 Mar 2000)
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