| low sodium syndrome | <syndrome> A syndrome resulting from salt restriction and use of diuretics in treatment of congestive heart failure and hypertension, characterised by weakness, drowsiness, muscle cramps, and a reduction in glomerular filtration with consequent nitrogen retention, renal failure, and sometimes death; occurs also in cirrhosis of the liver with ascites and in adrenal insufficiency. Synonym: salt depletion syndrome. (05 Mar 2000) |
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| low spinal anaesthesia | Spinal anaesthesia in which the level of sensory denervation extends to the tenth or eleventh thoracic dermatome. (05 Mar 2000) |
| low tension glaucoma | Optic nerve atrophy and excavation with typical field defects of glaucoma but without abnormal increase in intraocular pressure. (05 Mar 2000) |
| low tone deafness | Inability to hear low notes or frequencies. (05 Mar 2000) |
| low wine | The first weak distillate obtained from the mash in the process of making whisky. (05 Mar 2000) |
| lymphoma, low-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively favourable survival potential. (12 Dec 1998) |
| adenovirus e1a proteins | Proteins transcribed from the e1a region of adenovirus which are involved in positive regulation of transcription of the early genes. (12 Dec 1998) |
| adenovirus e1b proteins | Proteins transcribed from the e1b region of adenovirus which are involved in regulation of the levels of early and late gene expression. (12 Dec 1998) |
| adenovirus e1 proteins | The very first viral gene products synthesised after cells are infected with adenovirus. The e1 region of the genome has been divided into two major transcriptional units, e1a and e1b, each expressing proteins of the same name (adenovirus e1a proteins and adenovirus e1b proteins). (12 Dec 1998) |
| adenovirus e2 proteins | Proteins transcribed from the e2 region of adenovirus. Several of these are required for viral DNA replication. (12 Dec 1998) |
| adenovirus e3 proteins | Proteins transcribed from the e3 region of adenovirus but not essential for viral replication. The e3 19k protein mediates adenovirus persistence by reducing the expression of class I major histocompatibility complex antigens on the surface of infected cells. (12 Dec 1998) |
| adenovirus e4 proteins | Proteins transcribed from the e4 region of adenovirus. The e4 19k protein transactivates transcription of the adenovirus e2f protein and complexes with it. (12 Dec 1998) |
| adenovirus early proteins | <molecular biology, protein, virology> Proteins encoded by adenoviruses that are synthesised prior to, and in the absence of, viral DNA replication. The proteins are involved in both positive and negative regulation of expression in viral and cellular genes, and also affect the stability of viral mRNA. Some are also involved in oncogenic transformation. (12 Dec 1998) |
| amino acids, peptides, and proteins | Amino acids and chains of amino acids connected by peptide linkages. (12 Dec 1998) |
| androgen-binding proteins | Carrier proteins produced in the sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. Participate in the transport of androgens; include also synthetic androgens binding proteins. (12 Dec 1998) |