| immunodeficiency | Inabillity to mount a normal immune response. Immunodeficiency can be due to a genetic disease or acquired as in aids due to HIV. (12 Dec 1998) |
|---|---|
| immunodeficiency disorders | <radiology> B-cell (antibody) deficiency: high-grade pathogens: pneumococcus, strep, H. Flu, chronic sinopulmonary disease, usual survival to adulthood, T-cell (cellular) deficiency: low-grade pathogens: fungi, viruses, Pneumocystic, growth retardation, diarrhoea, delayed anergy, short life-span, susceptible to graft vs. Host (GvH) disease, e.g.: DiGeorge syndrome, Nezelhof syndrome Note: increased risk of malignancy (12 Dec 1998) |
| immunodeficiency syndrome | <syndrome> An immunological deficiency or disorder, of which the chief symptom is an increased susceptibility to infection, the pattern of susceptibility being dependent upon the kind of deficiency. See: immunodeficiency. (05 Mar 2000) |
| immunodeficiency virus, bovine | A species of lentivirus, subgenus bovine lentiviruses (lentiviruses, bovine), found in cattle and causing lymphadenopathy, lymphocytosis, central nervous system lesions, progressive weakness, and emaciation. It has immunological cross-reactivity with other lentiviruses including HIV. (12 Dec 1998) |
| immunodeficiency virus, feline | A species of lentivirus, subgenus feline lentiviruses (lentiviruses, feline) isolated from cats with a chronic wasting syndrome, presumed to be immune deficiency. There is no antigenic relationship between fiv and HIV, nor does fiv grow in human T-cells. (12 Dec 1998) |
| immunodeficiency with elevated IgM | Immunodeficiency with reduced IgG and IgA-bearing cells; there is recurrent pyogenic infection; X-linked in some families. (05 Mar 2000) |
| immunodeficiency with hypoparathyroidism | diGeorge syndrome |
| immunodeficient | Those diseases in which immune reactions are suppressed or reduced. Reasons may include congenital absence of B and/or T lymphocytes or viral killing of helper lymphocytes (see HIV). (18 Nov 1997) |
| immunodepressant | <immunology, pharmacology> An agent capable of suppressing immune responses. (18 Nov 1997) |
| immunodepression | See immunosuppression. (12 Dec 1998) |
| immunodepressor | <immunology, pharmacology> An agent capable of suppressing immune responses. (18 Nov 1997) |
| immunodiagnosis | The process of determining specified immunologic characteristics of individuals or of cells, serum, or other biologic specimens. (05 Mar 2000) |
| immunodiagnostic | A medical diagnostic based on the highly specific interaction between an antibody and an antigen. The antibody is used to detect the presence of the antigen. Monoclonal antibodies have come to be used in over 20 percent of all medical diagnostic procedures. (14 Nov 1997) |
| immunodiffusion | <technique> The classical technique used to detect the presence of antibodies and determine their specificity by visualisation of precipitin lines. A technique for analysing antigen and antibody mixtures by watching them as they diffuse toward each other within a support medium (usually a gel). The precipitin lines (precipitated antigen-antibody complexes) form where the binding concentrations of antigen and antibody are equivalent. Patient serum diffuses from one well through the gel and reacts with a known specific antigen (or antibody) which diffuses through the gel from a second well. Immunodiffusion is strictly qualitative, although the density of the precipitin line and the distance of the line from the sample well may give some indication of the antibody concentration. Synonym: double diffusion, Ouchterlony technique. (01 Dec 1998) |
| immunodominant epitopes | Subunits of the antigenic determinant that are most easily recognised by the immune system and thus most influence the specificity of the induced antibody. (12 Dec 1998) |