| granulomatosis | Any condition characterised by multiple granulomas. (05 Mar 2000) |
|---|---|
| granulomatosis siderotica | A form in which firm, brown foci that contain iron pigment (Gamna bodies) are present in an enlarged spleen. (05 Mar 2000) |
| granulomatous | Having the characteristics of a granuloma. (05 Mar 2000) |
| granulomatous arteritis | giant cell arteritis |
| granulomatous colitis | Changes, identical to those of regional enteritis, involving the colon. (05 Mar 2000) |
| granulomatous disease | <disease> Chronic granulomatous disease is usually fatal in childhood, in which the production of hydrogen peroxide by phagocytes does not occur because of a lesion in an NADP dependent oxidase. Catalase negative bacteria are not killed and there is no luminol enhanced chemiluminescence when the cells are tested. The absence of the oxygen dependent killing mechanism is not itself fatal but seriously compromises the primary defense system. at least three separate lesions can cause the syndrome, the commonest being a defect in plasma membrane cytochrome. Acronym: CGD (12 Jan 1998) |
| granulomatous disease, chronic | A recessive x-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. (12 Dec 1998) |
| granulomatous encephalomyelitis | An encephalomyelitis in which granulomas occur. (05 Mar 2000) |
| granulomatous endophthalmitis | A diffuse, chronic inflammation of intraocular tissues. (05 Mar 2000) |
| granulomatous enteritis | Crohn's disease, a chronic inflammatory disease of the intestine primarily in the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus. Named after Burrill Crohn who described the disease in 1932. The disease usually affects persons in their teens or early twenties. It tends to be a chronic, recurrent condition with periods of remission and exacerbation. In the early stages, Crohn's disease causes small scattered shallow crater-like areas (erosions) called apthous ulcers in the inner surface of the bowel. With time, deeper and larger ulcers develop, causing scarring and stiffness of the bowel and the bowel becomes increasingly narrowed, leading to obstruction. Deep ulcers can puncture holes in the bowel wall, leading to infection in the abdominal cavity (peritonitis) and in adjacent organs.When only the large intestine (colon) is involved, the condition is called Crohn's colitis. When only the small intestine is involved, the condition is called crohn's enteritis. When only the end of the small intestine (the terminal ileum) is involved, it is termed terminal ileitis. When both the small intestine and the large intestine are involved, the condition is called crohn's enterocolitis (or ileocolitis). Abdominal pain, diarrhoea, vomiting, fever, and weight loss can be symptoms. Crohn's disease can be associated with reddish tender skin nodules, and inflammation of the joints, spine, eyes, and liver. Diagnosis is by barium enema, barium X-ray of the small bowel, and colonoscopy. Treatment includes medications for inflammation, immune suppression, antibiotics, or surgery. (the disease is also called regional enteritis). (12 Dec 1998) |
| granulomatous ileitis | Crohn's disease involving the ileum (the lowest portion of the small intestine). (12 Dec 1998) |
| granulomatous inflammation | A form of proliferative inflammation See: granuloma. (05 Mar 2000) |
| granulomatous mastitis | A rare granulomatous inflammation of lobular breast tissue, with multinucleated giant cells; sarcoidosis is excluded by the frequent presence of neutrophils and absence of involvement of other tissues. (05 Mar 2000) |
| granulomatous meningoencephalomyelitis | A sporadic disease of dogs characterised by incoordination, ataxia, cervical pain, nystagmus, circling, seizures, and depression. (05 Mar 2000) |
| granulomatous nocardiosis | A form of nocardiosis characterised by emaciation, abdominal distention, and replacement of lymphoid tissue in lymph nodes and spleen by granulomatous tissue. (05 Mar 2000) |