| succinyl-CoA | The condensation product of succinic acid and CoA; one of the intermediates of the tricarboxylic acid cycle and a precursor in the synthesis of haem. Synonym: active succinate, succinyl-CoA. (05 Mar 2000) |
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| succinyl-CoA hydrolase | <enzyme> Enzyme from trichosporon cutaneum; acts on succinyl-CoA and methylsuccinyl CoA to give free acids Registry number: EC 3.1.2.3 Synonym: methylsuccinyl-CoA hydrolase, succinyl-coenzyme a hydrolase (26 Jun 1999) |
| succinyl-CoA ligase | A ligase reversibly reacting succinate and CoA with ATP to produce ADP, inorganic phosphate, and succinyl-CoA, a similar synthetase, but one able to use itaconate as well as succinate and GTP (or ITP) in place of ATP; a part of the tricarboxylic acid cycle. Synonym: succinic thiokinase, succinyl-CoA ligase. (05 Mar 2000) |
| succinyl-CoA synthetase | A ligase reversibly reacting succinate and CoA with ATP to produce ADP, inorganic phosphate, and succinyl-CoA, a similar synthetase, but one able to use itaconate as well as succinate and GTP (or ITP) in place of ATP; a part of the tricarboxylic acid cycle. Synonym: succinic thiokinase, succinyl-CoA ligase. (05 Mar 2000) |
| succinyl-CoA-tetrahydrodipicolinate N-succinyltransferase | <enzyme> Catalyses formation of CoA and n-succinyl-2-amino-6-keto-l-pimelate from succinyl-CoA and tetrahydrodipicolinate Registry number: EC 2.3.1.- Synonym: tetrahydrodipicolinate succinylase, tetrahydrodipicolinate n-succinyltransferase, succinyl-coenzyme a-tetrahydrodipicolinate n-succinyltransferase (26 Jun 1999) |
| D-3-hydroxyacyl CoA dehydratase | <enzyme> From rat liver peroxisomes; catalyses the epimerization of d-3-hydroxyacyl CoA by the dehydration of 3-hydroxyacyl-CoA to 2-trans-enoyl-CoA followed by the hydration of the latter enzyme to l-3-hydroxyacyl-CoA by enoyl-CoA hydratase (EC 4.2.1.17); is not active on 2-cis-enoyl CoA; consider also EC 4.2.1.74 Registry number: EC 4.2.1.- Synonym: d-3-hydroxyacyl coenzyme a dehydratase, beta-hydroxyacyl-CoA dehydratase (26 Jun 1999) |
| delta(3,5),delta(2,4)-dienoyl-CoA isomerase | <enzyme> Catalyses the isomerization of 3,5-octadienoyl-CoA to 2,4-octadienoyl-CoA Registry number: EC 5.3.3.- Synonym: ddd-CoA-isomerase, delta(3,5),t(2,4)-dienoyl-CoA isomerase (26 Jun 1999) |
| deoxycholoyl-CoA synthetase | <enzyme> Catalyses the synthesis of deoxycholoyl-CoA from deoxycholic acid in rat liver Registry number: EC 6.2.1.- Synonym: deoxycholic acid CoA ligase, deoxycholate CoA ligase, deoxycholoyl-coenzyme a synthetase (26 Jun 1999) |
| dicarboxylic acid-CoA oxidase | <enzyme> Oxidises dicarboxylic acid CoA esters using molecular oxygen and producing hydrogen peroxide, ultimately producing a dicarboxylic acid with 2 fewer carbon atoms Registry number: EC 1.3.3.- Synonym: dicarboxylyl-CoA oxidase, dicarboxylic acid-coenzyme a oxidase (26 Jun 1999) |
| dicarboxylic acid-CoA synthetase | <enzyme> Converts dicarboxylic acids (c5-c16) into their mono-CoA esters in the presence of ATP Registry number: EC 6.2.1.- Synonym: dicarboxylyl-CoA ligase, dicarboxylic acid-coenzyme a synthetase (26 Jun 1999) |
| dodecanoyl-CoA synthetase | <enzyme> Fatty acid thiokinase (long-chain), a ligase forming acyl-CoA, AMP, and pyrophosphate from long-chain fatty acids, ATP, and coenzyme A. Activity is independent of phosphatidylcholine Registry number: EC 6.2.1.3 Synonym: acyl-activating enzyme, dodecanoyl-CoA synthetase, fatty acid thiokinase (long chain), acid-coenzyme a ligase, fatty acid-CoA ligase, acyl-CoA synthetase, acyl-CoA ligase, coash ligase, ciprofibroyl-CoA synthetase, pristanoyl-CoA synthetase, palmityl CoA synthetase, palmitoyl CoA synthetase, palmitoyl CoA ligase, fatty acyl-CoA synthetase, very long chain fatty acid acyl-CoA synthetase, vlcfa acyl-CoA synthetase, nafenopin-CoA ligase, palmitoyl-CoA synthase, faa2 gene product, faa2p protein, vlacs enzyme (26 Jun 1999) |
| isobutyryl-CoA mutase | <enzyme> Catalyses conversion of butyryl-CoA to isobutyryl-CoA Registry number: EC 5.4.99.- (26 Jun 1999) |
| isovaleryl-CoA | The condensation product of isovaleric acid and coenzyme A; an intermediate in the catabolism of l-leucine. Synonym: isovalerylcoenzyme A. Isovaleryl-CoA dehydrogenase, an enzyme that participates in the catabolism of l-leucine; it converts isovaleryl-CoA to 3-methylcrotonyl-CoA using FAD; a deficiency in this enzyme will result in isovaleric acidemia. (05 Mar 2000) |
| octanoyl-CoA synthetase | Fatty acid thiokinase (medium chain), a ligase forming acyl-CoA's from medium-chain fatty acids and CoA with the conversion of ATP to AMP and PPi. A key step in activation of fatty acids. Synonym: acyl-activating enzyme, butyryl-CoA synthetase, octanoyl-CoA synthetase. (05 Mar 2000) |
| oleyl-CoA | A product of the d9-desaturase enzyme system in the biosynthesis of monounsaturated fatty acids. Synonym: oleyl-coenzyme A. (05 Mar 2000) |