| lymphocytic lymphoma | <oncology, tumour> A cancer of lymphatic tissues, the tumour cells are mostly abnormal lymphocytes. (13 Nov 1997) |
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| lymphoma | <oncology, tumour> Malignant tumour of lymphoblasts derived from B lymphocytes. most commonly affects children in tropical Africa: both Epstein Barr virus and immunosuppression due to malarial infection are involved. (18 Nov 1997) |
| lymphoma, aids-related | B-cell lymphoid tumours that occur in association with aids. Patients often present with an advanced stage of disease and highly malignant subtypes including burkitt lymphoma, immunoblastic large-cell lymphoma, small non-cleaved-cell lymphoma and diffuse large-cell lymphoma. The tumours are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in aids is a complex result of ebv infection, HIV antigenic stimulation, and T-cell-dependent HIV activation. (12 Dec 1998) |
| lymphoma, B-cell | A group of heterogeneous lymphoid tumours generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. (12 Dec 1998) |
| lymphoma, follicular | Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centres of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular centre B-lymphocytes. This class of lymphoma usually occurs in older persons, is commonly multinodal, and possibly extranodal. Patients whose lymphomas present a follicular or nodular pattern generally have a more indolent course than those presenting with a diffuse pattern. (12 Dec 1998) |
| lymphoma, high-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively unfavorable survival potential. (12 Dec 1998) |
| lymphoma, intermediate-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have an intermediate survival potential. (12 Dec 1998) |
| lymphoma, low-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively favourable survival potential. (12 Dec 1998) |
| lymphoma, lymphoblastic | A high-grade malignant lymphoma composed of a diffuse, relatively uniform proliferation of cells with round or convoluted nuclei and scanty cytoplasm. The cells are cytologically similar to the lymphoblasts seen in acute lymphocytic leukaemia, and in some cases, the disease may evolve into a leukaemic phase morphologically indistinguishable from acute t-lymphocytic leukaemia (leukaemia, T-cell, acute). Lymphoblastic lymphoma represents approximately one-third of the cases of non-hodgkin's lymphomas in children and 5% of the cases in adults. It is more prevalent in males. (12 Dec 1998) |
| lymphoma, mixed-cell | Malignant lymphoma characterised by the presence of a mixed population of cells, with the smaller cells resembling lymphocytes and the larger ones histiocytes. It usually presents in a nodular (follicular) pattern, but may evolve into a diffuse pattern. (12 Dec 1998) |
| lymphoma, mixed-cell, follicular | A low-grade malignant lymphoma of follicular pattern in which there is no clear preponderance of one cell type (small or large) over another. The large cells, cleaved or noncleaved, are often 2-3 times larger in diameter than normal lymphocytes. (12 Dec 1998) |
| lymphoma, mucosa-associated lymphoid tissue | Extranodal lymphoma of lymphoid tissue associated with mucosa that is in contact with exogenous antigens. Many of the sites of these lymphomas, such as the stomach, salivary gland, and thyroid, are normally devoid of lymphoid tissue. They acquire malt tissue as a result of an immunologically mediated disorder. (12 Dec 1998) |
| lymphoma, non-hodgkin | Any of a group of malignant tumours of lymphoid tissue that differ from hodgkin disease, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumours is the absence of giant reed-sternberg cells, a characteristic of hodgkin's disease. (12 Dec 1998) |
| lymphoma, small-cell | A B-cell lymphoma presumably representing a tumour of interfollicular B-lymphocytes that may be functional. Those that are secrete identical immunoglobulin molecules. (12 Dec 1998) |
| lymphoma, small cleaved-cell, follicular | A low-grade malignant lymphoma of predominantly follicular pattern. Follicles are of relatively uniform size and shape and the cells are usually somewhat larger than normal lymphocytes. Nuclei are irregular with prominent indentations and cytoplasm can rarely be identified. Cells exhibiting these characteristics are often called centrocytes. (12 Dec 1998) |