complement : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 8

Complement C8 - 새창 A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.
Synonyms : C8 Complement, Complement 8, Complement Component 8, Complement Component C8 alpha, Complement Component C8 alpha Chain, Complement Component C8 beta, Complement Component C8 beta Chain, Complement Component C8 gamma, Complement Component C8 gamma Chain
Complement C9 - 새창 A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
Synonyms : C9 Complement, Complement 9, Complement Component 9, C9, Complement, Complement, C9, Component 9, Complement
Complement Factor B - 새창 A glycine-rich, heat-labile serum glycoprotein that contains a component of the ALTERNATIVE COMPLEMENT C3 CONVERTASE (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.
Synonyms : Bb Fragment of Factor B, Complement Factor B Fragment, Bb, Complement Factor B, Alternative Pathway, Complement Factor B-Derived Fragment Bb, Complement Factor Ba, Complement Factor Bb, Complement Protein B, Complement Protein Factor B, Properdin Factor Ba
Complement Factor D - 새창 A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
Synonyms : 28 kDa Protein, Adipocyte, C3 Proactivator Convertase, C3PAse, Complement Protein D, D Component of Complement, GBGase, Proactivator Convertase, Activator, C3 Convertase, Complement D Component, Convertase Activator, C3, Convertase, C3 Proactivator
Complement Factor H - 새창 An important soluble regulator of the alternative pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It is a 139-kDa glycoprotein expressed by the liver and secreted into the blood. It binds to COMPLEMENT C3B and makes iC3b (inactivated complement 3b) susceptible to cleavage by COMPLEMENT FACTOR I. Complement factor H also inhibits the association of C3b with COMPLEMENT FACTOR B to form the C3bB proenzyme, and promotes the dissociation of Bb from the C3bBb complex (COMPLEMENT C3 CONVERTASE, ALTERNATIVE PATHWAY).
Synonyms : Factor H, Complement