| AAR | active avoidance reaction; acute articular rheumatism; antigen-antiglobulin reaction |
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| AB | abdominal; abnormal; abortion; Ace bandage; active bilaterally; aid to the blind; alcian blue; alert... |
| ABC | absolute basophil count; absolute bone conduction; acalculous biliary colic; acid balance control; a... |
| ABL | abetalipoproteinemia; acceptable blood loss; African Burkitt lymphoma; Albright-Butler-Lightwood [sy... |
| ABP | actin-binding protein; ambulatory blood pressure; American Board of Pedodontics; American Board of P... |
| O-antigen polymerase | <enzyme> Involved in the binding of o-antigen repeat units and in polymerizing into the o-antigen chain; mw 43.7 kD; genbank x71970 Registry number: EC 2.4.1.- Synonym: rfc protein, s. Flexneri, rfc gene product, o-antigen polymerase, shigella, o-antigen polymerase, pseudomonas, rfc protein, pseudomonas, o-antigen polymerase, e. Coli (26 Jun 1999) |
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| organ-specific antigen | A heterogenetic antigen with organ specificity; e.g., in addition to species-specific antigen, kidney of one species contains antigen that is identical to that in kidney of other species. Synonym: tissue-specific antigen. (05 Mar 2000) |
| Tac antigen | An antigenic determinant of the human interleukin 2 receptor that is identified by a murine monoclonal antibody, anti-Tac. Binding of this antigen prevents the proliferation of T-cells, which is normally stimulated by binding interleukin-2. (05 Mar 2000) |
| T antigen | <molecular biology> Proteins coded by viral genes that are expressed early in the replication cycle of papovaviruses such as SV40 and polyoma. Essential for normal viral replication, they are also expressed in nonpermissive cells transformed by these viruses. Originally detected as Tumour antigens by immunofluorescence with antisera from tumour bearing animals. SV40 has two, large T and small t, polyoma has three, large, middle and small. Appear to be collectively responsible for transformation by these viruses. (14 Oct 1997) |
| T-cell antigen receptors | Receptors present on T-cells that interact with both processed antigen and major histocompatibility antigens simultaneously. (05 Mar 2000) |
| T-dependent antigen | An antigen that requires T helper cells in addition to appropriate B-cells. Most antigens are T-dependent. (05 Mar 2000) |
| theta antigen | A surface glycoprotein that is present on thymocytes of mice and rats. (05 Mar 2000) |
| thymus-independent antigen | An antigen that does not require T helper cell activation in order for the host's B-cells to be stimulated. Repeating polymers such as polysaccharides are examples of T-independent antigens. (05 Mar 2000) |
| tissue polypeptide antigen | Serological tumour marker composed of a molecular complex of cytokeratins 8, 18, and 19. It is used in the diagnosis and staging of bronchogenic carcinoma. (12 Dec 1998) |
| tissue-specific antigen | A heterogenetic antigen with organ specificity; e.g., in addition to species-specific antigen, kidney of one species contains antigen that is identical to that in kidney of other species. Synonym: tissue-specific antigen. (05 Mar 2000) |
| TL antigen | <immunology> The mouse antigens coded for by the TLa complex, in normal animals only found on intrathymic lymphocytes, but also seen on leukaemic cells (hence, thymus leukaemia antigen) in certain forms of the disease in mice. The molecules have structures similar in some ways to Class I MHC products but are disulphide bonded tetramers of two 45 kD chains and two 12 kD chains of _2 microglobulin type. (18 Nov 1997) |
| transplantation antigen | <immunology> Any antigen that is antigenically active in graft rejection. In practice the major histocompatibility complex and the H Y antigens and to a lesser extent minor histocompatibility antigens. (18 Nov 1997) |
| Epithelial membrane antigen | <cell biology> Heavily glycosylated membrane glycoprotein. Encoded by the MUC 1 gene, has a molecular weight of around 300 kD, more than half of which is O linked glycan. There is a 69 residue cytoplasmic domain and the extracellular domain may extend hundreds of nanometres beyond the plasma membrane, the increased expression in carcinoma cells may reduce the adhesion and mask antigenic properties of the cells. Similar functions are ascribed to ASGP, epiglycanin and leucosialin. (18 Nov 1997) |
| tumour-associated antigen | Antigens that are highly correlated with certain tumour cells. They are not usually found, or are found to a lesser extent, on normal cells. (05 Mar 2000) |
| tumour specific antigen | <immunology, oncology> Antigen on tumour cells detected by cell-mediated immunity. For virus transformed cells TSTA (unlike T antigen) is found to differ for different individual tumours induced by the same virus. May consist of fragments of T antigens exposed at the cell surface. (18 Nov 1997) |
Synonyms : CD34 Antigen, Antigen, CD34
Synonyms : Adipocyte Membrane Protein p88, CD36 Antigen, CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor), CD36 Fatty Acid Transporter, CD36 Protein, FAT (Fatty Acid Translocase) - CD36 Antigen, GPIIIb Platelet Glycoprotein, GPIV Platelet Glycoprotein
Synonyms : ADPR Cyclase CD38, ADPR Cyclase T10, Acute Lymphoblastic Leukemia Cells Antigen CD38, CD38 Antigen, Lymphocyte Differentiation Antigen CD38, NIM-R5 Antigen, T10 Antigen, Antigen, T10, CD38, ADPR Cyclase, Cyclase CD38, ADPR, Cyclase T10, ADPR, NIM R5 Antigen
Synonyms : CD4 Antigen, Receptors, Surface CD4, Surface CD4 Receptor, Antigen, CD4, Antigens, T-Cell T4, CD4 Receptor, Surface, CD4 Receptors, Surface, Surface CD4 Receptors, T-Cell T4 Antigens, T4 Antigens, T Cell
Synonyms : CD40 Antigen, CDw40 Antigen, TNFRSF5 Receptor, Antigen, CD40, Antigen, CDw40, Receptor, TNFRSF5
| antigen |
Any foreign or "non-self" substance that, when introduced into the body, causes the immune system to create an antibody.
출처: www.i-bio.gov.uk/UkBioportal/Beginners/html/glossa...
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| antigen |
Any piece of a substance (foreign protein, toxin, bacteria) that can induce a specific immune response or react to a specific antibody or T-cell.
출처: www.aidsinfonyc.org/hivplus/issue9/report/glossary...
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| antigen-presenting cell |
A cell that can process an infectious agent and present pieces of it (antigens) to T-cells. Dendritic cells and macrophages function as APCs.
출처: www.aidsinfonyc.org/hivplus/issue9/report/glossary...
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| antigen g. |
the acquisition by cells of new antigenic determinants not normally present or not normally accessible in the parent tissue.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| antigen p. |
the activity in which macrophages ingest and partially digest antigens and then present the processed antigen on their surfaces to B and T lymphocytes. The presented antigen is more immunogenic than unprocessed antigen, possibly because it has been broken down into pieces more easily recognized by B and T cells, because it remains on the surface of the presenting cell for a long time, or because it is presented in association with self MHC antigen and thus able to stimulate helper T cells. The principal antigen-presenting cells are dendritic cells in B-dependent areas of lymphoid tissues, interdigitating cells in T-dependent areas, and Langerhans cells in the epidermis.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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