| alpha-mannosidase | <enzyme> Catalyses hydrolysis of terminal, non-reducing alpha-d-mannose residues in alpha-d-mannosides Registry number: EC 3.2.1.24 Synonym: alpha-d-mannoside mannohydrolase, alpha-d-mannosidase, neutral alpha-mannosidase, alpha mannosidase a, alpha mannosidase b, lysosomal alpha-mannosidase, laman (26 Jun 1999) |
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| alpha-methylacyl-CoA racemase | <enzyme> Involved in catabolism of branched-chain fatty acids derived from isoprenoids; acts on pristanoyl-CoA and trihydroxycoprostanoyl-CoA, but not on 3-methyl branched-chain or linear-chain acyl coas; amino acid sequence has been determined; genbank u89905 (rat) and u89906 (mouse); also isolated from human liver Registry number: EC 5.1.99.- Synonym: meac CoA racemase (26 Jun 1999) |
| alpha-methyltyrosine | <chemical> An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma and decreases the frequency and severity of hypertensive attacks and related symptoms in most patients. (martindale, the extra pharmacopoeia, 30th ed) Pharmacological action: enzyme inhibitors. (12 Dec 1998) |
| alpha-msh | <chemical> A 13-amino acid peptide derived from the anterior pituitary gland in man and from the pars intermedia in lower vertebrates. Its amino acid sequence is identical to the first 13 amino acids of acth. It influences the formation of deposition of melanin in the body and produces colour changes in the skin of amphibians, fishes and reptiles. It is secreted in humans only during foetal life and occasionally during pregnancy. Chemical name: alpha-Melanotropin (pig) (12 Dec 1998) |
| alpha-N-acetyl-D-glucosaminidase | <enzyme> Believed to be deficient in sanfilippo syndrome type b Registry number: EC 3.2.1.50 Synonym: alpha-n-acetylglucosaminidase (26 Jun 1999) |
| alpha-N-acetylgalactosaminidase | <enzyme> An enzyme that hydrolyzes 2-acetamido-2-deoxy-alpha-d-galactosides to the alcohol and free 2-acetamido-2-deoxy-d-galactose. A deficiency of this enzyme will result in Schindler disease. (05 Mar 2000) |
| alpha-N-acetylglucosaminidase | <enzyme> An enzyme that hydrolyzes glycosides of N-acetylglucosamine producing the alcohol and N-acetylglucosamine. A deficiency of this enzyme results in mucopolysaccharidosis III B. (05 Mar 2000) |
| alpha-N-acylamino acid hydrolase | <enzyme> Functions in catabolism of n-acetylamino acids resulting from turnover of alpha-n-acetylated proteins Registry number: EC 3.5.1.- Synonym: alpha-n-acetylamino acid hydrolase, anaa-hase, n-acylaminoacyl-peptide hydrolase (26 Jun 1999) |
| alpha-naphthylthiourea | 1-(1-Naphthyl)-2-thiourea;a derivative of thiourea; a highly toxic antithyroid agent, especially to small mammals, causing pulmonary oedema, fatty degeneration of the liver, and low body temperature; used as a rat poison. Acronym: ANTU (05 Mar 2000) |
| alpha-neoagarooligosaccharide hydrolase | <enzyme> Hydrolyzes the alpha-1,3 linkage of neoagarooligosaccharides; from marine bacterium, vibrio sp.; mw 42 kD; amino acid sequence has been determined Registry number: EC 3.2.1.- Synonym: alpha-naos hydrolase (26 Jun 1999) |
| alpha-oxidation | A form of oxidation of fatty acids in which carbons are removed one at a time in the form of CO2; the alpha-carbon is first hydroxylated and then converted into a carbonyl; a deficiency of this pathway is associated with Refsum's disease. (05 Mar 2000) |
| alpha-phenoxyethylpenicillin potassium | A penicillin preparation that is stable in gastric acid and is rapidly but only partially absorbed from the gastrointestinal tract. Synonym: alpha-phenoxyethylpenicillin potassium, penicillin B. (05 Mar 2000) |
| alpha-phenoxypropylpenicillin potassium | A semisynthetic acid-stable penicillin that may be more effective than penicillin G. Synonym: alpha-phenoxypropylpenicillin potassium. (05 Mar 2000) |
| alpha-pinene oxide lyase | <enzyme> From nocardia sp. Strain p18.3; catalyses the cleavage of both rings of the bicyclic structure with the formation of 2-methyl-5-isopropylhexa-2,5-dienal Registry number: EC 4.1.2.- Synonym: alpha-pinene oxide lyase (decyclizing) (26 Jun 1999) |
| alpha-prodine hydrochloride | See: alphaprodine. (05 Mar 2000) |
| kanamycin - alpha-hydroxy-gamma-aminobutyl acylase | <enzyme> Transforms kanamycin into amikacin Registry number: EC 2.3.1.- Synonym: alpha-hydroxy-gamma-aminobutyl acylase, haba acylase (26 Jun 1999) |
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| UDP-D-xylose-beta-D-glucoside alpha-1,3-xylosyltransferase | <enzyme> Catalyses transfer of xylose from udp-d-xylose to glucose Registry number: EC 2.4.2.- Synonym: udp-xyl-glc axt, beta-glucoside alpha-1,3-xylosyltransferase (26 Jun 1999) |
| UDP-D-xylose-xyloside alpha-1,3-xylosyltransferase | <enzyme> Catalyses transfer of xylose from udp-d-xylose to position 3 of xyl-1-3-glc-r' Registry number: EC 2.4.2.- Synonym: udp-xyl-xyl axt (26 Jun 1999) |
| UDP-galactose-lactosylceramide alpha 1-4-galactosyltransferase | <enzyme> Catalyses transfer of galactose from udp-galactose to lactosylceramide; exclusively an alpha1-4-galactosyltransferase Registry number: EC 2.4.1.- Synonym: udpgal-galactosyl-beta-1-4-glucosylceramide alpha1-4-galactosyltransferase, globotriaosylceramide synthase, udp-glcg-transferase, udp galactose lactosylceramide alpha-galactosyltransferase, udp-gal lcgtase, udp-gal-galactose alpha(1,4)-galactosyltransferase, alpha1,4galt (26 Jun 1999) |
| UDP-sulfoquinovose 1,2-diacylglycerol 3-O-alpha-D-sulfoquinovosyltransferase | <enzyme> Catalyses the final step in the synthesis of nucleoside 5'-diphospho-sulfoquinovoses Registry number: EC 2.4.1.- Synonym: usd-sulfoquinovosyltransferase, sqdd protein, sqdd gene product (26 Jun 1999) |
| KDO alpha-octulopyranoside hydrolase | <enzyme> Cleaves alpha-ketoside linkage in 3-deoxy-d-manno-2-octulosonic acid-containing capsular polysaccharides Registry number: EC 3.2.1.- Synonym: glycan kdop hydrolase (26 Jun 1999) |
| uridine 5'-(alpha-D-galactopyranosyl pyrophosphate) NAD 2-hexosyl oxidoreductase | <enzyme> Converts udpgalactose (pyranose form) to 2-keto-galactose which rearranges to furanose form Chemical name: UDPgalactose nad 2-hexosyl oxidoreductase Registry number: EC 1.1.1.- (26 Jun 1999) |
| 1,4-alpha-d | -glucan branching enzyme Amylo-(1,4→1,6)-transglucosylase or transglucosidase;an enzyme in muscle and in plants (Q enzyme) that cleaves alpha-1,4 linkages in glycogen or starch, transferring the fragments into alpha-1,6 linkages, creating branches in the polysaccharide molecules; in plants, it converts amylose to amylopectin; this enzyme is deficient in individuals with glycogen storage disease type IV. Synonym: alpha-glucan branching glycosyltransferase, amylo-1,4:1,6-glucantransferase, amylo-(1,4→1,6)-transglucosidase, amylo-(1,4→1,6)-transglucosylase, branching enzyme. (05 Mar 2000) |
| 1,4-alpha-glucan branching enzyme | <enzyme> In glycogen or amylopectin synthesis, the enzyme that catalyses the transfer of a segment of a 1,4-alpha-glucan chain to a primary hydroxy group in a similar glucan chain. Chemical name: 1,4-alpha-D-Glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase Registry number: EC 2.4.1.18 (12 Dec 1998) |
| 16 alpha-hydroxyprogesterone dehydratase | <enzyme> From rat intestinal anaerobic bacteria; forms 16-dehydroprogesterone Registry number: EC 4.2.1.- Synonym: 16 alpha-dehydratase (26 Jun 1999) |
| 17 alpha-hydroxyprogesterone aldolase | <enzyme> An enzyme of the lyase class that catalyses the cleavage of the bond between carbons 17 and 20 in 17-alpha hydroxyprogesterone to form delta 4-androstene-3,17-dione, an androgen. It also catalyses the conversion of 17 alpha-hydroxypregnenolone to dehydroepiandrosterone. Chemical name: 17 alpha-hydroxyprogesterone acetaldehyde-lyase Registry number: EC 4.1.2.30 (12 Dec 1998) |
| 24,25-dihydrolanosterol 14 alpha-oxidase | <enzyme> Oxidatively removes the 14 alpha-methyl group of sterols as formic acid; cytochrome p-450 dependent Registry number: EC 1.14.13.- Synonym: 14 alpha-methyl sterol oxidase (26 Jun 1999) |
| 2,4-dichlorophenoxyacetate-alpha-ketoglutarate dioxygenase | <enzyme> Encoded by the tfda gene of plasmide pjp4; an fe(ii)-dependent enzyme that catalyses the conversion of 2,4-dichlorophenoxyacetate to 2,4-dichlorophenol and glyoxylate concomitant with the deomposition of alpha-ketoglutarate to succinate and co2 Registry number: EC 1.14.11.- Synonym: 2,4-d-kdg (26 Jun 1999) |
| 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosyl-hydroxylysine glucohydrolase | <enzyme> Responsible for catabolism of hydroxylysine-linked disaccharide unit derived from collagen in mammals Registry number: EC 3.2.1.- Synonym: glc-gal-hyl glucohydrolase, ggh-glucohydrolase (26 Jun 1999) |
| 3 alpha-hydroxysteroid-5 beta-oxidoreductase | <enzyme> From digitalis lanata; specific for 5 beta-pregnan-3-ones; does not act on 5 alpha-pregnane-3-ones or delta 4/delta 5-pregnenes Registry number: EC 1.1.1- Synonym: 3a ohs oxidoreductase (26 Jun 1999) |