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thrombogen Synonym: prothrombin.
Origin: thrombo-+ G. -gen, producing
(05 Mar 2000)
thrombogene <chemical> Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor v accomplishes this by forming a complex with factor xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor v leads to owren's disease.
Chemical name: Blood-coagulation factor V
(12 Dec 1998)
thrombogenic <haematology, pharmacology> Causing thrombosis with clotting or coagulation of the blood.
Origin: Gr. Gennan = to produce
(15 Oct 1997)
thromboid Resembling a thrombus.
Origin: thrombo-+ G. Eidos, resemblance
(05 Mar 2000)
thrombokatilysin A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be haemophiliacs.
(12 Dec 1998)
thrombokinase <haematology> Traditional name for substance in plasma that converts prothrombin to thrombin. Now known not to be a single substance. (See thrombin).
(18 Nov 1997)
thrombolic Relating to a thrombolus.
(05 Mar 2000)
thrombolus An embolus composed of agglutinated platelets.
Origin: thrombo-+ G. Embolos, embolus
(05 Mar 2000)
thrombolymphangitis Inflammation of a lymphatic vessel with the formation of a lymph clot.
(05 Mar 2000)
thrombolysis Fluidifying or dissolving of a thrombus.
Origin: thrombo-+ G. Lysis, a dissolving
(05 Mar 2000)
thrombolytic 1. Dissolving or splitting up a thrombus.
2. <pharmacology> A thrombolytic agent.
Origin: Gr. Lysis = dissolution
(18 Nov 1997)
thrombolytic agent Medications that dissolve blot clots (for example streptokinase, tissue plasminogen activator or TPA and urokinase).
(27 Sep 1997)
thrombolytic medication Medications that dissolve blot clots (for example streptokinase, tissue plasminogen activator or TPA and urokinase).
(27 Sep 1997)
thrombolytic therapy The use of thrombolytic agents to dissolve blood clots to re-establish blood flow through an occluded vessel.
Examples of thrombolytic agents include: urokinase, streptokinase and tissue plasminogen activator (TPA). These agents may be introduced into a vein or selectively into a diseased (blocked) artery using a catheter.
(27 Sep 1997)
thrombomodulin <cell biology> Specific endothelial cell receptor (100 kD: luminal surface only) that forms a 1:1 complex with thrombin. This complex then converts protein C to Ca, that in turn acts on Factors Va and VIIIa. Structurally similar to coated pit receptors.
(18 Nov 1997)
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