| TSP | testis-specific protein; thrombin-sensitive protein; thrombospondin; total serum protein; total susp... |
|---|---|
| CAP | camptodactyly-arthropathy-pericarditis [syndrome]; Canada Assistance Plan; capsule; captopril; catab... |
| PEP | peptidase; phospho(enol)pyruvate; peer evaluation program; phosphoenolpyruvate; pigmentation, edema,... |
| PPD | packs per day; paraphenylenediamine; percussion and postural drainage; permanent partial disability;... |
| CHARGE | coloboma, heart disease, atresia choanae, retarded growth and retarded development and/or CNS anomal... |
| DNA, antisense | A DNA molecule which is complementary to the sense strand (that which functions as a template for the synthesis of mRNA) but is not involved in transcription. Both strands are involved in replication. (12 Dec 1998) |
|---|---|
| DNA-(apurinic or apyrimidinic site) lyase | <enzyme> Formerly EC 3.1.25.2 Registry number: EC 4.2.99.18 Synonym: endodeoxyribonuclease (apurinic or apyrimidinic), apurinic endonuclease, apurinic DNA endonuclease, purine insertase, endonuclease iv, DNA repair endonuclease, endonuclease vi, endonuclease iv, E coli, bap1, bovine ap endonuclease I, nfo gene product, apci, apcii, apciii, ap lyase, ap endonuclease, hap1 DNA repair enzyme, apurine-apyrimidine endonuclease (26 Jun 1999) |
| DNA, archaeal | Deoxyribonucleic acid that makes up the genetic material of archaea. (12 Dec 1998) |
| DNA, bacterial | Deoxyribonucleic acid that makes up the genetic material of bacteria. (12 Dec 1998) |
| DNA beta-glucosyltransferase | <enzyme> Transfers a beta-d-glucosyl residue from udp-glucose to hydroxymethylcytosine residues in double-stranded DNA Registry number: EC 2.4.1.27 Synonym: udp-glucose-DNA beta-d-glucosyltransferase, udp-glucose - 5-hydroxymethylcytosine beta-glucosyltransferase (26 Jun 1999) |
| DNA-binding proteins | Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases. (12 Dec 1998) |
| DNA, chloroplast | Deoxyribonucleic acid that makes up the genetic material of chloroplasts. (12 Dec 1998) |
| DNA, circular | Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (12 Dec 1998) |
| DNA cloning | The use of DNA manipulation procedures to produce multiple copies of a single gene or segment of DNA. (12 Dec 1998) |
| DNA, complementary | Single-stranded complementary DNA synthesised from an RNA template by the action of RNA-dependent DNA polymerase. Cdna (i.e., complementary DNA, not circular DNA, not c-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe. (12 Dec 1998) |
| DNA (cytosine-5-)-methyltransferase | <enzyme> An enzyme that catalyses the transfer of a methyl group from s-adenosylmethionine to the 5-position of cytosine or to the 6-position in adenine in mammalian DNA. Chemical name: S-Adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase Registry number: EC 2.1.1.37 (12 Dec 1998) |
| DNA damage | Drug- or radiation-induced injuries in DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions which interfere with replication and transcription, as well as point mutations which disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair). If the damage is extensive, it can induce apoptosis. (12 Dec 1998) |
| DNA delta-helicase | <enzyme> From foetal calf thymus; partially copurifies with DNA polymerase delta; also has DNA-dependent atpase activity Registry number: EC 3.6.1.- (26 Jun 1999) |
| DNA deoxyribophosphodiesterase | <enzyme> From E coli; catalyses the release of deoxyribose phosphate residues from polydeoxyribonucleotide 5'-termini Registry number: EC 3.1.4.- Synonym: drpase (26 Jun 1999) |
| DNA-dependent ATPase | <enzyme> Factor y is a phage 174 specific DNA-dependent atpase; atpase I can act with double-stranded DNA; atpase II and III require single-stranded DNA; a18r from vaccinia virus Registry number: EC 3.6.1.- Synonym: DNA helicase II, factor y, DNA-dependent atpase I, DNA-dependent atpase II, DNA-dependent atpase III, rep protein (E coli), atpase, DNA-dependent, DNA-dependent atpase iv, uvrd protein, rep helicase, pri a protein, protein n', rip100, pria helicase, pria protein (helicase), a18r gene product, DNA helicase a (26 Jun 1999) |